About The Saban Research Institute

The Saban Research Institute comprises basic, translational and clinical research at Children’s Hospital Los Angeles – one of the few freestanding pediatric hospitals in the country where scientific inquiry is combined with clinical care devoted exclusively to children.

The Institute’s interdisciplinary research is organized around three synergistic areas of focus that together fully explore the developmental origins of health and disease and address the most pressing national child health issues:

Originally established in 1992, The Children’s Hospital Research Institute became The Saban Research Institute in 2003 following a $40 million gift in support of pediatric research made by Cheryl Saban, PhD, Haim Saban and the Saban Family Foundation.

The Saban Research Institute and CHLA maintain strong scientific and strategic affiliations with the University of Southern California (USC) and the Keck School of Medicine of USC, where our physicians and scientists hold faculty appointments. The Institute’s researchers also are involved in collaborative projects with academic institutions throughout the U.S. and abroad.

The Saban Research Institute of Children’s Hospital Los Angeles is among the largest and most productive pediatric research centers in the western United States.

With $129.9 million in total research funding and $32.4 million in National Institutes of Health (NIH) funding, the efforts of more than 237 principal investigators are aligned into four inclusive research themes: Best Starts to Life, From Discovery to Pediatric Care Innovation, Personalized Prevention and Care, and Pediatric Disease Models and Mechanisms. The hospital is eighth in the nation among children’s hospitals for NIH funding.

Research Programs

Community, Health Outcomes and Intervention Research
Developmental Biology and Regenerative Medicine
Developmental Neuroscience
Diabetes and Obesity
Children’s Health Imaging Research Program
Infection Therapeutic and Prevention Program

Research Facilities

The Saban Research Institute building and Smith Research Tower provide more than 150,000 square feet of bench laboratory space dedicated to research conducted by more than 450 research faculty  who collaborate with clinicians in all sub-specialties across the hospital.

Laboratory scientists are supported by sophisticated shared core facilities that include: genomics, gene targeting and pathology, proteomics, biostatistics, cellular imaging, fluorescence activation cell sorting (FACS), Mi Next Generation Science (MiNGS), stem cell, vector and research imaging.

The Clinical Research Support Office at Children’s Hospital Los Angeles provides resources that enable investigators to perform high-quality, patient-oriented research at various venues throughout the hospital and the community.