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DISCOVERIES AND INNOVATION

Mental Healthcare ... in the NICU?

Bringing a baby into the world involves many firsts – mothers and fathers are discovering their new roles, babies are learning what it means to live outside the womb, and the family is forging a relationship and bonding. But what happens when this time of uncertainty is complicated by medical issues?

Many infants born premature or with other complications often forego their first weeks or months at home for a stay in...

What Makes a Cell Turn Cancerous?

A cancer gene called MYCN (red) appears in high levels in cone cells (green). These cone cells can go on to form retinoblastoma tumors. Image provided by Dr. Hardeep Singh, Children’s Hospital Los Angeles.

Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age and accounts for approximately 4% of childhood cancers. If not diagnosed early, retinoblastoma may result...

Our #WomenInScience Rock!

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They wear lab coats in place of capes, safety goggles instead of masks, and wield pipets - not swords. But they are still our heroes.

At CHLA, we are proud to honor women in science for International Women’s Day!

Please visit www.chla.org/womeninscience to learn about 6 talented women who are saving lives from the laboratory.

RESEARCH COMMUNITY

Peter Chiarelli, MD, PhD Wins Prestigious Award for Nanoparticle Research

When it comes to pediatric brain cancers, research and treatments have made great strides. But some cancers do not respond to conventional treatments or grow deep within delicate areas of the brain, where surgical removal can be impossible.

Peter Chiarelli, MD, PhD, has received an award to support his research in...

Precision Medicine for Pediatric Cancer

Research performed over the last several decades has led to an increased understanding of the genetics of cancer. The clinical application of this knowledge for pediatric cancer has lagged behind studies performed for adults. In a perspectives article published in the prestigious journal Science, Dr. Jaclyn Biegel, from Children’s Hospital Los...

Children’s Hospital Los Angeles Hosts 10th Annual St. Baldrick’s Head Shave Event

For the tenth year in a row, doctors, family members, and the Los Angeles community came together to support cancer research at the St. Baldrick’s Annual Head Shave Event. This year’s event held particular significance for one of CHLA’s doctors, Robert Seeger, MD, MS (pictured below), who shaved his head for the 10th and final time.

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NEWS

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Children’s Hospital Los Angeles researcher awarded $3.7M to study neural circuits associated with developmental disorders. Pat Levitt, PhD, Chief Scientific Officer at Children’s Hospital Los Angeles and Simms/Mann Chair in Developmental Neurogenetics, received a $3.7M grant...
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Doctors at Children’s Hospital Los Angeles use novel software to improve accuracy of cancer treatment Doctors at Children’s Hospital Los Angeles continue to lead the field of radiation oncology by pushing the leading edge of technological advances. A new report by Arthur...
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Stress creates risk, maternal education provides resilience   A study of 70 mothers and their infants suggests that the impact of maternal stress on neurodevelopment is detectable by electroencephalography (EEG) at 2 months of age. The team of investigators, co-led...

Research videos

  • Family Philanthropy Benefits Research on Nephrology

    A documentary film about the GOFARR Fund for Children’s Hospital Los Angeles was recently screened at the Sun Valley Film Festival for Future Filmmakers. The film, “Believe: The Story of the GOFARR Fund,” was made by Amanda Schenkman and tells the story about her twin brother Gabriel and his journey with a congenital kidney condition.

    The Schenkman Family Fund supports nephrology research at CHLA overseen by Roger De Filippo, MD, FACS, FAAP and Laura Perin, PhD. At the GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology, De Filippo and Perin focus on the development of new stem cell therapeutics and other techniques for organ regeneration.

  • Using Gene-Editing to Cure Type 1 Diabetes

    Senta Georgia, PhD, is creating new insulin-producing cells using CRISPR gene-editing technology in her work to cure genetic forms of diabetes.

  • Can Virtual Reality Help Manage Pain?

    Researchers at CHLA are studying the use of virtual reality to reduce pain in children and adolescents undergoing painful medical procedures. Jeffrey Gold, PhD, a clinical psychologist and director of the Pediatric Pain Management Clinic, explains his research.

  • Using Virtual Reality to Train Physicians for Pediatric Emergencies

    CHLA is using virtual reality to build skills and confidence to prepare medical students for real-life emergencies. Joshua Sherman, MD, an emergency medicine physician at CHLA, explains how.

  • Protecting the Brains of Infants with Therapeutic Cooling

    Investigators at Children's Hospital Los Angeles are using therapeutic cooling to protect the brains of newborns deprived of oxygen during birth. Jessica Wisnowski, PhD, and Tai-Wei Wu, MD, explain the process and why it works.