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DISCOVERIES AND INNOVATION

I Heart Zebrafish

How a fish smaller than a pinky finger holds big clues to saving hearts

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What do zebrafish and newborn babies have in common? Both are small, yet hold vast potential for the future. But these two organisms are more intertwined than you might think.

Ching-Ling (Ellen) Lien, PhD, of Children’s Hospital Los Angeles studies zebrafish because of their...

Wired for Obesity

Scientists pinpoint a set of genes that may wire the body weight center of the brain

Eating and exercise have the power to shape our bodies but those activities are controlled by hard-wired circuits in the brain. This means that when these neural circuits are developing is a critical time for determining how our brains will regulate our body weight, even in adulthood. What remains a mystery is just how these circuits achieve the...

What Can Blood Flow Tell Us About Autism?

With autism diagnoses on the rise, science is on the hunt for answers. New research at Children’s Hospital Los Angeles uses advanced imaging techniques to uncover some clues.

Each year, one in 59 children are diagnosed with Autism Spectrum Disorder (ASD), a condition that impacts a child’s social, emotional, and behavioral development. The rate of diagnosis has grown, tripling in the last 15 years. While...

RESEARCH COMMUNITY

Enough! Time for Tech to Help Kids with Autism

1 out of 68 children in the United States will be diagnosed with an Autism Spectrum Disorder (ASD). The prevalence of an ASD diagnosis grew by 72 percent between 2007 and 2011. Tech-based interventions targeted to children with autism have the potential to help solve challenges with social skills, repetitive behaviors, speech and nonverbal communications.

At the South by Southwest Interactive Healthcare...

American Pediatric Society 2018 Elected Members From CHLA

(Left to Right) Douglas Nordli, Jr., MD, CHLA Chief of Pediatric Neurology; Robert E. Shaddy, MD, CHLA Pediatrician-in-Chief; Rohit Kohli, MBBS, MS, CHLA Chief of Gastroenterology, Hepatology, and Nutrition.

This year, three physician researchers at Children’s Hospital Los Angles representing subspecialties in gastroenterology, neurology and cardiology,  have been elected to the membership of...

David Warburton is among the 2017 AAAS Elected Fellows Recognized for Advancing Science in the Section of Medical Sciences

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David Warburton, MD, has been elected a 2017 Fellow of the American Association for the Advancement of Science (AAAS) in recognition his contributions to innovation, education, and scientific leadership in the Section of Medical Sciences...

NEWS

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Research at Children’s Hospital Los Angeles brings us closer to understanding an elusive symptom of sickle cell disease – the silent stroke. Sickle Cell Disease (SCD) is rare but devastating. Due to a genetic mutation affecting hemoglobin, the component of the red blood cell...
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With autism on the rise, science is on the hunt for answers. New research at Children’s Hospital Los Angeles looks at autism in a different way. One in 59 children are diagnosed with an Autism Spectrum Disorder (ASD), a wide array of conditions affecting a child’s social,...
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How one doctor born and raised in a tightly knit Filipino culture is poised to dramatically improve the health and well-being of her community Mental health and suicide are not just adult issues. According to the Centers for Disease Control and Prevention, suicide rates have...

Research videos

  • Family Philanthropy Benefits Research on Nephrology

    A documentary film about the GOFARR Fund for Children’s Hospital Los Angeles was recently screened at the Sun Valley Film Festival for Future Filmmakers. The film, “Believe: The Story of the GOFARR Fund,” was made by Amanda Schenkman and tells the story about her twin brother Gabriel and his journey with a congenital kidney condition.

    The Schenkman Family Fund supports nephrology research at CHLA overseen by Roger De Filippo, MD, FACS, FAAP and Laura Perin, PhD. At the GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology, De Filippo and Perin focus on the development of new stem cell therapeutics and other techniques for organ regeneration.

  • Using Gene-Editing to Cure Type 1 Diabetes

    Senta Georgia, PhD, is creating new insulin-producing cells using CRISPR gene-editing technology in her work to cure genetic forms of diabetes.

  • Can Virtual Reality Help Manage Pain?

    Researchers at CHLA are studying the use of virtual reality to reduce pain in children and adolescents undergoing painful medical procedures. Jeffrey Gold, PhD, a clinical psychologist and director of the Pediatric Pain Management Clinic, explains his research.

  • Using Virtual Reality to Train Physicians for Pediatric Emergencies

    CHLA is using virtual reality to build skills and confidence to prepare medical students for real-life emergencies. Joshua Sherman, MD, an emergency medicine physician at CHLA, explains how.

  • Protecting the Brains of Infants with Therapeutic Cooling

    Investigators at Children's Hospital Los Angeles are using therapeutic cooling to protect the brains of newborns deprived of oxygen during birth. Jessica Wisnowski, PhD, and Tai-Wei Wu, MD, explain the process and why it works.