Research Blog
Published on August 5, 2016

Five physician-scientists
with the Center for Childhood Cancer and Blood Diseases at Children’s Hospital
Los Angeles recently received grants from the St. Baldrick’s Foundation, the
largest private funder of childhood cancer research. Theirs are just some of
the innovative... Read More
Published on August 2, 2016

Osteoporosis is a major problem in public health with
significant costs both in healthcare dollars and human potential. Generally
known as a condition effecting older women, and to a lesser extent, older men,
this condition originates in childhood. Fragile bones can also occur... Read More
Published on July 29, 2016

A study led by researchers at The Saban Research Institute
of Children’s Hospital Los Angeles (CHLA) suggests that maternal HIV infection
influences the microbiome of their HIV-uninfected infants. Their findings, reported online in the
journal Science Translational Medicine
on... Read More
Published on July 26, 2016

A study by researchers at Children’s Hospital Los Angeles
(CHLA), Brigham and Women’s Hospital and the California Department of Public
Health suggests that all babies with a known mutation for cystic
fibrosis (CF) and second mutation called the 5T allele should receive... Read More
Published on July 22, 2016

Regulating how the gut microbiome interacts with the immune system may
protect the intestine from injury by decreasing inflammationInflammatory Bowel Disease (IBD) causes immeasurable
suffering to those afflicted and costs our society about $1.2 billion annually.At its core, IBD... Read More
Published on July 19, 2016

Marketing junk food to kids A recent study confirms
what parents and food companies have known for years – advertisements aimed at
kids are effective. We’ve all seen a young child, seated in the shopping cart –
reaching longingly for a brightly colored box of cereal displaying... Read More
Published on July 15, 2016

Robert Seeger, MD
(center), in 1991Cell lines, or populations of identical cells maintained in
a laboratory, are fundamental to even the most basic of biomedical research.
With a thriving cell line, researchers do not have to rely on precious, and
often rare, patient samples.“... Read More
Published on July 12, 2016

While rare, a percentage of congenital craniofacial
abnormalities may indicate a risk of developing cancer. This critical insight may
change the course of treatment in order to ensure the best possible outcome for
patients.Seemingly straightforward craniofacial conditions, such... Read More
Published on July 8, 2016

What happens in early childhood can matter for a lifetime.Pediatricians are growing increasingly alarmed about the
dangers of so-called “toxic stress”—chronic activation of a young child’s
stress response systems due to repeated, uncontrollable adverse events, which
can alter... Read More
Published on July 5, 2016

Sudden Infant Death Syndrome (SIDS), the unexplained sudden
death of an infant under the age of one year, affects approximately 1500
infants annually. Its exact cause remains a mystery, but a recent study
in Pediatrics has revealed a possible
risk factor. Researchers have found... Read More
Published on July 1, 2016

One family’s health scare leads to new hope for children with brain and
spinal cord tumorsErika Kort had just finished dance class when her legs
started to feel numb. Thinking she probably just pulled a muscle, the
16-year-old wasn’t concerned until the sensation began spreading... Read More
Published on June 28, 2016

Many clinicians don’t feel confident about treating kids with autism
and related mental health disorders, which may come as no surprise to parents
of children with autism spectrum disorders (ASD). Up to 70% of children with ASD have a co-occurring mental
health disorder such as... Read More
Published on June 24, 2016

How kids’ intuitive use
of technology advances care at Children’s Hospital Los AngelesSometimes it seems like today’s kids were born with a cell
phone in hand, intuitively searching the Web and sharing selfies on Instagram.
These “digital natives” have been immersed in... Read More
Published on June 22, 2016

Researchers at The Saban Research Institute of Children’s
Hospital Los Angeles have identified a new genetic candidate for testing
therapies that might affect fear learning in people with PTSD or other
conditions. Results of the study have been published in the Journal of... Read More
Published on June 21, 2016

Neurons
in the hypothalamus develop abnormally in Prader-Willi Syndrome
A
study published in the journal Human
Molecular Genetics
by researchers at Children’s Hospital Los Angeles (CHLA) provides novel
insights into the brain mechanisms underlying the... Read More
Published on June 17, 2016

Bench to Bassinet research into congenital heart disease at CHLACardiothoracic surgeon Richard Kim, MD, is interested in doing more than basic research alone.“I want to do research that has a real impact on our patients,” he says, “with results that I can see in my lifetime.”... Read More
Published on June 15, 2016

Tracy C. Grikscheit, MD, pediatric surgeon and principal
investigator at The Saban Research Institute of Children’s Hospital Los
Angeles, treats a large number of young patients who require surgery for
various intestinal diseases. Since the
intestinal microbiome is an important... Read More
Published on June 14, 2016

Pediatric residents
prepare for the next big earthquakeWhile experts agree that the West Coast is due for a sizable
earthquake, there is little consensus as to when such an event may hit. Therefore,
preparation will be a key component to survival and good outcomes for major... Read More
Published on June 8, 2016

Screening of thousands of
children in California suggests which mutations are disease-causing and which are
benignWhen it comes to cystic
fibrosis (CF), more than 2,000 different genetic mutations have been reported. However, only 200 of them have been
categorized – leaving a... Read More
Published on June 3, 2016

Optimizing Adult Treatments for Pediatric Patients with Glaucoma and
Cataracts “My goal is to decrease childhood blindness by treating
pediatric eye disease in an innovative way,” says Bibiana Jin Reiser, MD, MS,
director of the Cornea and
Glaucoma Institute at The Vision Center... Read More