Research Blog
Published on September 14, 2016
In a first-of-its-kind look at human kidney development,
researchers at The Saban Research Institute of Children’s Hospital Los Angeles
have isolated human nephron progenitor (NP) cells. Their results, published online in the
journal Stem Cell Translational Medicine,
will help... Read More
Published on September 9, 2016
Surface of the mouse colon repaired by stem cells after a flare of
ulcerative colitis. The different colors show the contributions of individual
stem cells as they have multiplied to patch the breaks, or ulcers, in the
colonic surface. These ulcers were originally caused by the... Read More
Published on September 6, 2016
Genetic Intersection of Conditions AnalyzedResearchers at the Institute for the Developing Mind at Children’s
Hospital Los Angeles have analyzed current gene-disease findings to understand
why people with neurodevelopmental and mental illness often have physical
disorders.Their... Read More
Published on August 30, 2016
biodegradable scaffold (left) and human tissue-engineered liver (right)A research team led by investigators at The Saban Research Institute of Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.... Read More
Published on August 26, 2016
Delirium is an acute neurologic dysfunction, defined by the
DSM IV as an acute change in consciousness with impairments in attention and
cognition. Over the decades critical care literature has referred to the
condition with a variety of terms, most commonly ICU
psychosis.... Read More
Published on August 23, 2016
An article aimed at kids 10 to 15-years old by researchers
Elizabeth R. Sowell, PhD, Kristina Uban and Megan Herting from Children’s Hospital
Los Angeles asks the provocative question: Imagine that your family was given a
million dollars. How would your life
change?
The article... Read More
Published on August 19, 2016
In an innovative, first-in-pediatrics study, available only at Children’s
Hospital Los Angeles (CHLA), researchers will be enrolling children between 1
and 18 years of age who have certain types of relapsed or treatment-resistant
cancer.The aim of this investigator-initiated... Read More
Published on August 16, 2016
Study suggests substantial complications may impact
daily activities, long after initial cancer diagnosisA team of researchers from nine leading academic hospitals
and research centers have published a paper in the early online edition of the
journal Cancer
that describes... Read More
Published on August 9, 2016
Limiting screen time is often talked about for middle- and
high school students. But, should
parents worry about how much time their preschoolers are spending in front of a
tablet? While adults and caregivers find it easy to entertain or
distract little kids with a smart phone... Read More
Published on August 5, 2016
Five physician-scientists
with the Center for Childhood Cancer and Blood Diseases at Children’s Hospital
Los Angeles recently received grants from the St. Baldrick’s Foundation, the
largest private funder of childhood cancer research. Theirs are just some of
the innovative... Read More
Published on August 2, 2016
Osteoporosis is a major problem in public health with significant costs both in healthcare dollars and human potential. Generally known as a condition effecting older women, and to a lesser extent, older men, this condition originates in childhood. Fragile bones can also occur... Read More
Published on July 29, 2016
A study led by researchers at The Saban Research Institute
of Children’s Hospital Los Angeles (CHLA) suggests that maternal HIV infection
influences the microbiome of their HIV-uninfected infants. Their findings, reported online in the
journal Science Translational Medicine
on... Read More
Published on July 26, 2016
A study by researchers at Children’s Hospital Los Angeles
(CHLA), Brigham and Women’s Hospital and the California Department of Public
Health suggests that all babies with a known mutation for cystic
fibrosis (CF) and second mutation called the 5T allele should receive... Read More
Published on July 22, 2016
Regulating how the gut microbiome interacts with the immune system may protect the intestine from injury by decreasing inflammationInflammatory Bowel Disease (IBD) causes immeasurable suffering to those afflicted and costs our society about $1.2 billion annually.At its core, IBD... Read More
Published on July 19, 2016
Marketing junk food to kids A recent study confirms
what parents and food companies have known for years – advertisements aimed at
kids are effective. We’ve all seen a young child, seated in the shopping cart –
reaching longingly for a brightly colored box of cereal displaying... Read More
Published on July 15, 2016
Robert Seeger, MD
(center), in 1991Cell lines, or populations of identical cells maintained in
a laboratory, are fundamental to even the most basic of biomedical research.
With a thriving cell line, researchers do not have to rely on precious, and
often rare, patient samples.“... Read More
Published on July 12, 2016
While rare, a percentage of congenital craniofacial
abnormalities may indicate a risk of developing cancer. This critical insight may
change the course of treatment in order to ensure the best possible outcome for
patients.Seemingly straightforward craniofacial conditions, such... Read More
Published on July 5, 2016
Sudden Infant Death Syndrome (SIDS), the unexplained sudden
death of an infant under the age of one year, affects approximately 1500
infants annually. Its exact cause remains a mystery, but a recent study
in Pediatrics has revealed a possible
risk factor. Researchers have found... Read More
Published on June 28, 2016
Many clinicians don’t feel confident about treating kids with autism
and related mental health disorders, which may come as no surprise to parents
of children with autism spectrum disorders (ASD). Up to 70% of children with ASD have a co-occurring mental
health disorder such as... Read More
Published on June 24, 2016
How kids’ intuitive use
of technology advances care at Children’s Hospital Los AngelesSometimes it seems like today’s kids were born with a cell
phone in hand, intuitively searching the Web and sharing selfies on Instagram.
These “digital natives” have been immersed in... Read More