Research Blog

Published on September 14, 2016
In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have isolated human nephron progenitor (NP) cells.  Their results, published online in the journal Stem Cell Translational Medicine, will help... Read More
Published on September 9, 2016
Surface of the mouse colon repaired by stem cells after a flare of ulcerative colitis. The different colors show the contributions of individual stem cells as they have multiplied to patch the breaks, or ulcers, in the colonic surface. These ulcers were originally caused by the... Read More
Published on September 6, 2016
Genetic Intersection of Conditions AnalyzedResearchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles have analyzed current gene-disease findings to understand why people with neurodevelopmental and mental illness often have physical disorders.Their... Read More
Published on August 30, 2016
biodegradable scaffold (left) and human tissue-engineered liver (right)A research team led by investigators at The Saban Research Institute of Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.... Read More
Published on August 26, 2016
Delirium is an acute neurologic dysfunction, defined by the DSM IV as an acute change in consciousness with impairments in attention and cognition. Over the decades critical care literature has referred to the condition with a variety of terms, most commonly ICU psychosis.... Read More
Published on August 23, 2016
An article aimed at kids 10 to 15-years old by researchers Elizabeth R. Sowell, PhD, Kristina Uban and Megan Herting from Children’s Hospital Los Angeles asks the provocative question: Imagine that your family was given a million dollars.  How would your life change? The article... Read More
Published on August 19, 2016
In an innovative, first-in-pediatrics study, available only at Children’s Hospital Los Angeles (CHLA), researchers will be enrolling children between 1 and 18 years of age who have certain types of relapsed or treatment-resistant cancer.The aim of this investigator-initiated... Read More
Published on August 16, 2016
Study suggests substantial complications may impact daily activities, long after initial cancer diagnosisA team of researchers from nine leading academic hospitals and research centers have published a paper in the early online edition of the journal Cancer that describes... Read More
Published on August 9, 2016
Limiting screen time is often talked about for middle- and high school students. But, should parents worry about how much time their preschoolers are spending in front of a tablet? While adults and caregivers find it easy to entertain or distract little kids with a smart phone... Read More
Published on August 5, 2016
Five physician-scientists with the Center for Childhood Cancer and Blood Diseases at Children’s Hospital Los Angeles recently received grants from the St. Baldrick’s Foundation, the largest private funder of childhood cancer research. Theirs are just some of the innovative... Read More
Published on August 2, 2016
Osteoporosis is a major problem in public health with significant costs both in healthcare dollars and human potential. Generally known as a condition effecting older women, and to a lesser extent, older men, this condition originates in childhood. Fragile bones can also occur... Read More
Published on July 29, 2016
A study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) suggests that maternal HIV infection influences the microbiome of their HIV-uninfected infants.  Their findings, reported online in the journal Science Translational Medicine on... Read More
Published on July 26, 2016
A study by researchers at Children’s Hospital Los Angeles (CHLA), Brigham and Women’s Hospital and the California Department of Public Health suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive... Read More
Published on July 22, 2016
Regulating how the gut microbiome interacts with the immune system may protect the intestine from injury by decreasing inflammationInflammatory Bowel Disease (IBD) causes immeasurable suffering to those afflicted and costs our society about $1.2 billion annually.At its core, IBD... Read More
Published on July 19, 2016
Marketing junk food to kids A recent study confirms what parents and food companies have known for years – advertisements aimed at kids are effective. We’ve all seen a young child, seated in the shopping cart – reaching longingly for a brightly colored box of cereal displaying... Read More
Published on July 15, 2016
Robert Seeger, MD (center), in 1991Cell lines, or populations of identical cells maintained in a laboratory, are fundamental to even the most basic of biomedical research. With a thriving cell line, researchers do not have to rely on precious, and often rare, patient samples.“... Read More
Published on July 12, 2016
While rare, a percentage of congenital craniofacial abnormalities may indicate a risk of developing cancer. This critical insight may change the course of treatment in order to ensure the best possible outcome for patients.Seemingly straightforward craniofacial conditions, such... Read More
Published on July 5, 2016
Sudden Infant Death Syndrome (SIDS), the unexplained sudden death of an infant under the age of one year, affects approximately 1500 infants annually. Its exact cause remains a mystery, but a recent study in Pediatrics has revealed a possible risk factor. Researchers have found... Read More
Published on June 28, 2016
Many clinicians don’t feel confident about treating kids with autism and related mental health disorders, which may come as no surprise to parents of children with autism spectrum disorders (ASD). Up to 70% of children with ASD have a co-occurring mental health disorder such as... Read More
Published on June 24, 2016
How kids’ intuitive use of technology advances care at Children’s Hospital Los AngelesSometimes it seems like today’s kids were born with a cell phone in hand, intuitively searching the Web and sharing selfies on Instagram. These “digital natives” have been immersed in... Read More