Research Blog

Published on September 30, 2015
Children’s Hospital Los Angeles Awarded $8 Million as Part of Landmark NIH Study to Find the AnswerAs part of a landmark study about the effects of adolescent substance use on the developing brain called the Adolescent Brain Cognitive Development (ABCD) study, Children’s... Read More
Published on September 28, 2015
The gastrointestinal (GI) tract, which includes the stomach and intestines, is controlled by the enteric nervous system (ENS), which functions almost like a “second brain” controlling the movement of food throughout the tract and its digestion. The ENS is embedded within the GI... Read More
Published on September 25, 2015
Investigators at Children’s Hospital Los Angeles have found that a common therapeutic target for the treatment of inflammatory bowel disease (IBD) may actually protect against intestinal inflammation or colitis by inhibiting pathogenic T immune cells. This discovery, reported in... Read More
Published on September 19, 2015
Researchers at Children’s Hospital Los Angeles have received an $8.4 million grant from the National Institutes of Health (NIH) to conduct research to improve HIV care and prevention in a study focusing on Black, Latino and multiracial gay and bisexual young men – a group at the... Read More
Published on September 16, 2015
New model allows researchers to visualize an embryo as it grows Featured on the cover of the August issue of Development, this image shows the development of heart and dorsal arteries using 30 still images from a time-lapsed movie generated using a new transgenic... Read More
Published on September 4, 2015
CHLA researcher Elizabeth Sowell, PhD, was featured on NPR’s Marketplace Morning Report on Thursday, September 3 for her research study finding an association between socioeconomic status and brain development. Check out her interview here as well as our own post below from... Read More
Published on August 26, 2015
Cross-section of mouse gastrocnemius muscle, courtesy of Lily Chao, MD, Children’s Hospital, Los AngelesImportant for quick leg movements like running and jumping, the gastrocnemius muscle is connected to the Achilles tendon and spans the back of the lower leg. Researchers at... Read More
Published on August 26, 2015
medresearch: Curcumin Shows Potential to Prevent Inflammation-Associated Cancer and Restore Gut Ecology Researchers at the University of Arizona Steele Children’s Research Center have made another promising discovery about curcumin—the bioactive ingredient in turmeric—as a... Read More
Published on August 25, 2015
Seeing the arm ripped off of one’s favorite SpongeBob SquarePants plush pillow can be heartbreaking for a child. But rather than grieve its loss, a young Michael Quintero got out his mother’s sewing kit and slowly stitched SpongeBob back together. While too young to truly... Read More
Published on August 21, 2015
Like the beautiful corals that line sea reefs (right), lung epithelial cells (left) line the many branches of airways in your lungs through which air is collected and distributed to incoming red blood cells, which carry oxygen to the rest of the body.Researchers at CHLA are... Read More
Published on August 20, 2015
In a word? Data.Left: The Great Library of Alexandria, O. Von Corven, 1st Century, Public DomainRight: Big Data Image, Courtesy of Shutterstock “The library of Alexandria was a great data repository,” began Randall Wetzel, MD, during a presentation at Children’s... Read More
Published on August 17, 2015
Researchers demonstrate better outcomes using immune therapy drug called alemtuzumab in transplant patients with non-malignant genetic diseases of blood cellsComputer modeling of the monoclonal antibody alemtuzumab, which CHLA researchers have shown helps reduce graft rejections... Read More
Published on August 10, 2015
Functional MRI of brain activity during a spatial N-back task.Ever wonder how the brain figures out what we need to learn? What we need to remember? What we can forget? A clue lies in understanding what’s called “working memory”, which holds information temporarily and processes... Read More
Published on August 7, 2015
When life gives you lemons, make some lemonade.Alexandra “Alex” Scott gave new meaning to the saying when, at the age of four, she began selling lemonade to fund pediatric cancer research. She had been diagnosed with neuroblastoma, a pediatric cancer of the sympathetic nervous... Read More
Published on August 5, 2015
Researchers at Children’s Hospital Los Angeles, led by principal investigator and acting division head of Neurology Wendy Mitchell, MD, have been at the forefront of studying treatment and outcome Opsoclonus-Myoclonus Syndrome or OMS (also known as the “dancing eyes” syndrome or... Read More
Published on August 3, 2015
How should we approach and study Johanson-Blizzard Syndrome?Though incredibly rare, Johanson-Blizzard Syndrome (JBS) requires intervention from multiple medical fields. Complications this syndrome presents in many areas of the body can necessitate treatment over the course of... Read More
Published on July 31, 2015
In a recent article in the New York Times, being “fat” is reported to be the most common reason children are bullied.As obesity rates have risen, much emphasis has been placed on taking personal responsibility for body weight and changing behaviors. There is a perception that... Read More
Published on July 29, 2015
Difference aids in childbearing, but likely imparts a greater susceptibility for scoliosis and osteoporosis in females Looking at measurements of the vertebrae – the series of small bones that make up the spinal column – in newborn children, investigators at Children’s... Read More
Published on July 27, 2015
According to a recent article in The New York Times, a study published in the journal Circulation found that consumption of sugary drinks results in some 184,000 deaths worldwide each year. The study’s researchers further estimate that sweetened drinks cause 133,000 deaths from... Read More
Published on July 24, 2015
Researchers in the Division of Hematology, Oncology and Blood & Marrow Transplantation at Children’s Hospital Los Angeles have shown greatly improved outcomes in using stem cell transplantation to treat patients with a serious but very rare form of chronic blood cancer... Read More