Research Blog

Published on July 26, 2016
A study by researchers at Children’s Hospital Los Angeles (CHLA), Brigham and Women’s Hospital and the California Department of Public Health suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive... Read More
Published on July 22, 2016
Regulating how the gut microbiome interacts with the immune system may protect the intestine from injury by decreasing inflammationInflammatory Bowel Disease (IBD) causes immeasurable suffering to those afflicted and costs our society about $1.2 billion annually.At its core, IBD... Read More
Published on July 19, 2016
Marketing junk food to kids A recent study confirms what parents and food companies have known for years – advertisements aimed at kids are effective. We’ve all seen a young child, seated in the shopping cart – reaching longingly for a brightly colored box of cereal displaying... Read More
Published on July 15, 2016
Robert Seeger, MD (center), in 1991Cell lines, or populations of identical cells maintained in a laboratory, are fundamental to even the most basic of biomedical research. With a thriving cell line, researchers do not have to rely on precious, and often rare, patient samples.“... Read More
Published on July 12, 2016
While rare, a percentage of congenital craniofacial abnormalities may indicate a risk of developing cancer. This critical insight may change the course of treatment in order to ensure the best possible outcome for patients.Seemingly straightforward craniofacial conditions, such... Read More
Published on July 5, 2016
Sudden Infant Death Syndrome (SIDS), the unexplained sudden death of an infant under the age of one year, affects approximately 1500 infants annually. Its exact cause remains a mystery, but a recent study in Pediatrics has revealed a possible risk factor. Researchers have found... Read More
Published on June 28, 2016
Many clinicians don’t feel confident about treating kids with autism and related mental health disorders, which may come as no surprise to parents of children with autism spectrum disorders (ASD). Up to 70% of children with ASD have a co-occurring mental health disorder such as... Read More
Published on June 24, 2016
How kids’ intuitive use of technology advances care at Children’s Hospital Los AngelesSometimes it seems like today’s kids were born with a cell phone in hand, intuitively searching the Web and sharing selfies on Instagram. These “digital natives” have been immersed in... Read More
Published on June 22, 2016
Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Results of the study have been published in the Journal of... Read More
Published on June 21, 2016
Neurons in the hypothalamus develop abnormally in Prader-Willi Syndrome A study published in the journal Human Molecular Genetics by researchers at Children’s Hospital Los Angeles (CHLA) provides novel insights into the brain mechanisms underlying the... Read More
Published on June 17, 2016
Bench to Bassinet research into congenital heart disease at CHLACardiothoracic surgeon Richard Kim, MD, is interested in doing more than basic research alone.“I want to do research that has a real impact on our patients,” he says, “with results that I can see in my lifetime.”... Read More
Published on June 15, 2016
Tracy C. Grikscheit, MD, pediatric surgeon and principal investigator at The Saban Research Institute of Children’s Hospital Los Angeles, treats a large number of young patients who require surgery for various intestinal diseases.  Since the intestinal microbiome is an important... Read More
Published on June 14, 2016
Pediatric residents prepare for the next big earthquakeWhile experts agree that the West Coast is due for a sizable earthquake, there is little consensus as to when such an event may hit. Therefore, preparation will be a key component to survival and good outcomes for major... Read More
Published on June 8, 2016
Screening of thousands of children in California suggests which mutations are disease-causing and which are benignWhen it comes to cystic fibrosis (CF), more than 2,000 different genetic mutations have been reported.  However, only 200 of them have been categorized – leaving a... Read More
Published on May 27, 2016
CHLA Physician Todd Chang is using serious gaming as a tool to train young doctors Activity in the emergency department (ED) in a pediatric hospital is fast-paced, and the most precious resource is time. With more than 80,000 patients to attend to every year for trauma, rare... Read More
Published on May 25, 2016
The California Institute for Regenerative Medicine awards grant to CHLA researcher for CRISPR/Cas9 project to treat genetic diabetesOften touted as one of the most revolutionary biomedical technologies of the modern age, the CRISPR/Cas9 gene editing system has already led to new... Read More
Published on May 19, 2016
Carotid artery thickness is fueled by androgen hormones in cases of classical adrenal hyperplasia according to a new research study out of Children’s Hospital Los Angeles. This finding has significant implications for preventing cardiovascular disease in young adults. Youth with... Read More
Published on May 17, 2016
From the Eat 5 a Day initiative to increase fruit and vegetable consumption to First Lady Michelle Obama’s Let’s Move campaign, many efforts have been made to curb the growing incidence of childhood obesity. But a troubling new study suggests a lot more work needs to be done.... Read More
Published on May 13, 2016
While human genome studies can lead to medical breakthroughs in the diagnosis and treatment of various conditions, the subject of genome research can also aggravate sensitivities. And while the knowledge that some health problems are more prevalent among certain populations has... Read More
Published on May 9, 2016
From skin rashes and hives to difficulty breathing and more serious reactions, food allergies affect up to six million children in the United States alone. But over the last two decades, researchers have discovered it can also lead to another condition known as eosinophilic... Read More