Research Blog
Published on March 12, 2018

The
sidewalk was smooth and the sky was clear, so Sophia Cabrera took out her
skateboard and went for a ride. Before she could return home, she fell, landed
in a heap and broke her arm. Funny thing is, she and her family couldn’t have
been happier. Falls and fractures are... Read More
Published on March 5, 2018

Baby Jasmine was born in late December with
hypoplastic left heart syndrome (HLHS) and had her first open-heart surgery at
five days old. She is enrolled in the groundbreaking clinical trial at
Children’s Hospital Los Angeles. New
therapy could boost organ... Read More
Published on November 28, 2017

David Warburton, MD, has been
elected a 2017 Fellow of the American Association for the Advancement of
Science (AAAS) in recognition his contributions to innovation, education, and
scientific leadership in the Section of Medical Sciences. Warburton, who is the director of the... Read More
Published on November 14, 2017

A protein lining the inner layer of the heart. The protein is required for heart muscles
to proliferate during development.Ram Kumar
Subramanyan, MD, PhD, brings a unique point of view to the laboratory,
where his goal is to one day use stem cells to create replacement parts for... Read More
Published on November 7, 2017

The Sharon D. Lund Foundation has awarded $400,000 to Michele
Kipke, PhD, vice chair of Research and division head of Research
on Children, Youth and Families. The funding will support research efforts of
the Boone Fetter Clinic and the Institute for the Developing Mind to... Read More
Published on October 10, 2017

Investigators identify pathway that causes immune cells to
support cancer, instead of killing itInvestigators
at the
Children’s Center for Cancer and Blood Diseases
at Children’s Hospital
Los Angeles have identified new findings about an immune cell – called a
tumor-... Read More
Published on October 6, 2017

New Biomarker Assay Detects Neuroblastoma with Greater Sensitivity
Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when... Read More
Published on August 28, 2017

A Celebration and Seminar Honoring Robert C. Seeger, MD
A special celebration and research seminar
honoring Robert C. Seeger, MD, was held at the Saban Research
Institute on August 23, 2017. Seeger, who joined CHLA in 1989 as research
director in the Division of... Read More
Published on August 15, 2017

Study uses fMRI to observe
relationship between neurological activity and risk for obesityA team of researchers,
including senior investigator, Bradley Peterson, MD, director of the Institute
for the Developing Mind at Children’s Hospital Los Angeles, used fMRI to
investigate... Read More
Published on June 29, 2017

Two physicians
examine the challenges and benefits of using an age-old practice to toilet
train their infant daughter You
know that disposable diapers are ecologically questionable, but cloth diapers
seem too messy for you and your child – is there an alternative?The... Read More
Published on May 16, 2017

Signal processing technique improves analysis
of ultrasonic vocalizationsVocalization
plays a significant role in social communication across species such as speech
by humans and song by birds. Male mice produce ultrasonic vocalizations in the
presence of females and both sexes... Read More
Published on April 27, 2017

Christopher
Russell, MD, a hospitalist at Children’s Hospital Los Angeles specializing
in pediatric patients with tracheostomies, noticed that many of these children
have a high percentage of being re-admitted to the hospital for respiratory
conditions. A tracheostomy is a... Read More
Published on April 21, 2017

Willowbrook State School, Staten Island, NY 50 years ago, children with developmental disabilities such
as autism spectrum disorder (ASD) were routinely institutionalized
because families were ill-equipped to care for them.Today, thanks to research funded in part by the... Read More
Published on April 20, 2017
In 1963, the death
of baby Patrick Bouvier Kennedy, who was born 5 ½ weeks premature and died
from respiratory distress syndrome,
gripped the nation. At that time,
medicine had very little to offer premature babies with respiratory distress,
but baby Patrick’s death put a... Read More
Published on April 20, 2017
Twenty years ago, a child with inflammatory
arthritis had a very different life than a child with that same disease has
today. In 1997, that child suffered from chronic pain and lack of mobility that
kept them homebound – unable to go to school, have the opportunity to make... Read More
Published on April 18, 2017
“My goal is to decrease childhood blindness by treating
pediatric eye disease in an innovative way,” says Bibiana
Jin Reiser, MD, MS, director of the Cornea and Glaucoma Institute
at CHLA. Using technology developed for adults, she is optimizing it to treat
children.“The disease... Read More
Published on April 17, 2017
Research is a team sport. Each advance is incremental –
small but crucial in reaching the next, significant step toward finding a
solution. Science is currently under a great deal of scrutiny
because of how it is conducted
and how it is funded. At Children’s Hospital Los... Read More
Published on April 5, 2017

Zebrafish
heart with prominent coronary vessels (marked by transgenic fluorescent
reporters)Heart disease is among the leading causes of death for both
adults and children. A heart attack (or myocardial infarction) occurs when the
heart is deprived of oxygen due to blockage of a... Read More
Published on March 20, 2017

Brain scans of chronically depressed patients before and
during treatment. Left: Before treatment, depressed patients had a thicker
cortex in the frontal, temporal and parietal lobes of the brain (shown in red).
Right: Over 10 weeks of medication, these regions (shown in
blue)... Read More
Published on March 3, 2017

In a study led by Barbara
Driscoll, PhD, of The Saban Research Institute of Children’s Hospital Los
Angeles, researchers demonstrate, for the first time that inhaled resveratrol
treatments slow aging-related degenerative changes in mouse lung. Lung aging, characterized by... Read More