Research Blog
Published on August 28, 2017
A Celebration and Seminar Honoring Robert C. Seeger, MD
A special celebration and research seminar
honoring Robert C. Seeger, MD, was held at the Saban Research
Institute on August 23, 2017. Seeger, who joined CHLA in 1989 as research
director in the Division of... Read More
Published on August 15, 2017
Study uses fMRI to observe
relationship between neurological activity and risk for obesityA team of researchers,
including senior investigator, Bradley Peterson, MD, director of the Institute
for the Developing Mind at Children’s Hospital Los Angeles, used fMRI to
investigate... Read More
Published on June 29, 2017
Two physicians
examine the challenges and benefits of using an age-old practice to toilet
train their infant daughter You
know that disposable diapers are ecologically questionable, but cloth diapers
seem too messy for you and your child – is there an alternative?The... Read More
Published on May 16, 2017
Signal processing technique improves analysis
of ultrasonic vocalizationsVocalization
plays a significant role in social communication across species such as speech
by humans and song by birds. Male mice produce ultrasonic vocalizations in the
presence of females and both sexes... Read More
Published on April 27, 2017
Christopher
Russell, MD, a hospitalist at Children’s Hospital Los Angeles specializing
in pediatric patients with tracheostomies, noticed that many of these children
have a high percentage of being re-admitted to the hospital for respiratory
conditions. A tracheostomy is a... Read More
Published on April 21, 2017
Willowbrook State School, Staten Island, NY 50 years ago, children with developmental disabilities such
as autism spectrum disorder (ASD) were routinely institutionalized
because families were ill-equipped to care for them.Today, thanks to research funded in part by the... Read More
Published on April 20, 2017
In 1963, the death
of baby Patrick Bouvier Kennedy, who was born 5 ½ weeks premature and died
from respiratory distress syndrome,
gripped the nation. At that time,
medicine had very little to offer premature babies with respiratory distress,
but baby Patrick’s death put a... Read More
Published on April 20, 2017
Twenty years ago, a child with inflammatory
arthritis had a very different life than a child with that same disease has
today. In 1997, that child suffered from chronic pain and lack of mobility that
kept them homebound – unable to go to school, have the opportunity to make... Read More
Published on April 18, 2017
“My goal is to decrease childhood blindness by treating
pediatric eye disease in an innovative way,” says Bibiana
Jin Reiser, MD, MS, director of the Cornea and Glaucoma Institute
at CHLA. Using technology developed for adults, she is optimizing it to treat
children.“The disease... Read More
Published on April 17, 2017
Research is a team sport. Each advance is incremental –
small but crucial in reaching the next, significant step toward finding a
solution. Science is currently under a great deal of scrutiny
because of how it is conducted
and how it is funded. At Children’s Hospital Los... Read More
Published on April 5, 2017
Zebrafish
heart with prominent coronary vessels (marked by transgenic fluorescent
reporters)Heart disease is among the leading causes of death for both
adults and children. A heart attack (or myocardial infarction) occurs when the
heart is deprived of oxygen due to blockage of a... Read More
Published on March 20, 2017
Brain scans of chronically depressed patients before and
during treatment. Left: Before treatment, depressed patients had a thicker
cortex in the frontal, temporal and parietal lobes of the brain (shown in red).
Right: Over 10 weeks of medication, these regions (shown in
blue)... Read More
Published on March 3, 2017
In a study led by Barbara
Driscoll, PhD, of The Saban Research Institute of Children’s Hospital Los
Angeles, researchers demonstrate, for the first time that inhaled resveratrol
treatments slow aging-related degenerative changes in mouse lung. Lung aging, characterized by... Read More
Published on February 8, 2017
Brain activity of spider phobic people during repeated presentation
of pictures of spiders - when they were aware of them (left column),
and when they were not aware of them (right column). The phobic
people processed the spider pictures significantly more when they were not... Read More
Published on January 30, 2017
Investigators at Children’s Hospital Los Angeles, led by
Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short
bowel syndrome (SBS) using a novel zebrafish model and by performing intensive
gene sequencing. This approach to determining which genes are... Read More
Published on January 9, 2017
Characterized by repetition of sounds, syllables, or words;
prolongation of sounds; and interruptions in speech, stuttering occurs most often in children between the ages of
2 and 6 as they are developing their language skills. While 75 percent outgrow or recover
from stuttering... Read More
Published on January 3, 2017
Innate immune cells of the myeloid lineage
(primarily macrophages and neutrophils) surrounding the epithelial crypts in
inflamed colonic tissue.
Inflammatory Bowel Disease (IBD) is a debilitating,
incurable condition affecting approximately 1.5 million... Read More
Published on December 13, 2016
Doctors in training, known as medical
residents, often find themselves tasked with significant clinical
responsibilities while continuing to learn how to be a physician. Many
hospitals offer lecture conferences to supplement the education of residents,
but turnout to these... Read More
Published on December 6, 2016
Investigators from Children’s Hospital Los Angeles and 37
other Children’s Oncology Group hospitals in the U.S. and Canada have
determined that sodium thiosulfate prevents cisplatin-induced hearing loss in
children and adolescents with cancer. Results of this randomized,... Read More
Published on November 29, 2016
Differences in
Neural Density between Stuttering and Control Participants Blue: reduced neural density in stutterers; Red: increased neural density in stutterersResearchers at Children’s Hospital
Los Angeles (CHLA) have conducted the first study of its kind, using proton... Read More