Research Blog

Published on August 28, 2017
A Celebration and Seminar Honoring Robert C. Seeger, MD  A special celebration and research seminar honoring Robert C. Seeger, MD, was held at the Saban Research Institute on August 23, 2017. Seeger, who joined CHLA in 1989 as research director in the Division of... Read More
Published on August 15, 2017
Study uses fMRI to observe relationship between neurological activity and risk for obesityA team of researchers, including senior investigator, Bradley Peterson, MD, director of the Institute for the Developing Mind at Children’s Hospital Los Angeles, used fMRI to investigate... Read More
Published on June 29, 2017
Two physicians examine the challenges and benefits of using an age-old practice to toilet train their infant daughter You know that disposable diapers are ecologically questionable, but cloth diapers seem too messy for you and your child – is there an alternative?The... Read More
Published on May 16, 2017
Signal processing technique improves analysis of ultrasonic vocalizationsVocalization plays a significant role in social communication across species such as speech by humans and song by birds. Male mice produce ultrasonic vocalizations in the presence of females and both sexes... Read More
Published on April 27, 2017
Christopher Russell, MD, a hospitalist at Children’s Hospital Los Angeles specializing in pediatric patients with tracheostomies, noticed that many of these children have a high percentage of being re-admitted to the hospital for respiratory conditions.  A tracheostomy is a... Read More
Published on April 21, 2017
Willowbrook State School, Staten Island, NY   50 years ago, children with developmental disabilities such as autism spectrum disorder (ASD) were routinely institutionalized because families were ill-equipped to care for them.Today, thanks to research funded in part by the... Read More
Published on April 20, 2017
In 1963, the death of baby Patrick Bouvier Kennedy, who was born 5 ½ weeks premature and died from respiratory distress syndrome, gripped the nation.  At that time, medicine had very little to offer premature babies with respiratory distress, but baby Patrick’s death put a... Read More
Published on April 20, 2017
Twenty years ago, a child with inflammatory arthritis had a very different life than a child with that same disease has today. In 1997, that child suffered from chronic pain and lack of mobility that kept them homebound – unable to go to school, have the opportunity to make... Read More
Published on April 18, 2017
“My goal is to decrease childhood blindness by treating pediatric eye disease in an innovative way,” says Bibiana Jin Reiser, MD, MS, director of the Cornea and Glaucoma Institute at CHLA. Using technology developed for adults, she is optimizing it to treat children.“The disease... Read More
Published on April 17, 2017
Research is a team sport. Each advance is incremental – small but crucial in reaching the next, significant step toward finding a solution. Science is currently under a great deal of scrutiny because of how it is conducted and how it is funded.  At Children’s Hospital Los... Read More
Published on April 5, 2017
Zebrafish heart with prominent coronary vessels (marked by transgenic fluorescent reporters)Heart disease is among the leading causes of death for both adults and children. A heart attack (or myocardial infarction) occurs when the heart is deprived of oxygen due to blockage of a... Read More
Published on March 20, 2017
Brain scans of chronically depressed patients before and during treatment. Left: Before treatment, depressed patients had a thicker cortex in the frontal, temporal and parietal lobes of the brain (shown in red). Right: Over 10 weeks of medication, these regions (shown in blue)... Read More
Published on March 3, 2017
In a study led by Barbara Driscoll, PhD, of The Saban Research Institute of Children’s Hospital Los Angeles, researchers demonstrate, for the first time that inhaled resveratrol treatments slow aging-related degenerative changes in mouse lung.  Lung aging, characterized by... Read More
Published on February 8, 2017
Brain activity of spider phobic people during repeated presentation of pictures of spiders - when they were aware of them (left column), and when they were not aware of them (right column). The phobic people processed t​he spider pictures significantly more when they were not... Read More
Published on January 30, 2017
Investigators at Children’s Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome (SBS) using a novel zebrafish model and by performing intensive gene sequencing. This approach to determining which genes are... Read More
Published on January 9, 2017
Characterized by repetition of sounds, syllables, or words; prolongation of sounds; and interruptions in speech, stuttering occurs most often in children between the ages of 2 and 6 as they are developing their language skills. While 75 percent outgrow or recover from stuttering... Read More
Published on January 3, 2017
Innate immune cells of the myeloid lineage (primarily macrophages and neutrophils) surrounding the epithelial crypts in inflamed colonic tissue. Inflammatory Bowel Disease (IBD) is a debilitating, incurable condition affecting approximately 1.5 million... Read More
Published on December 13, 2016
Doctors in training, known as medical residents, often find themselves tasked with significant clinical responsibilities while continuing to learn how to be a physician. Many hospitals offer lecture conferences to supplement the education of residents, but turnout to these... Read More
Published on December 6, 2016
Investigators from Children’s Hospital Los Angeles and 37 other Children’s Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer. Results of this randomized,... Read More
Published on November 29, 2016
Differences in Neural Density between Stuttering and Control Participants Blue: reduced neural density in stutterers; Red: increased neural density in stutterersResearchers at Children’s Hospital Los Angeles (CHLA) have conducted the first study of its kind, using proton... Read More