Research Blog

Published on July 30, 2014
Just like our biceps or hamstrings, the heart can “tire out” after prolonged stress. But in serious cases, this muscle fatigue can cause our vital pumping organ to fail. One of the fundamental causes of this failure is the loss or damage of the heart’s muscle cells (... Read More
Published on July 25, 2014
Did you know that 1.6 million people were diagnosed with cancer last year, many of whom needed blood transfusions during chemotherapy? Because traditional cancer treatments like chemo- and radiation therapies can deplete the red blood cell-forming components in bone marrow,... Read More
Published on July 23, 2014
Reaching temperatures as low as -40 degrees Fahrenheit (an incomprehensible number, especially to Angelenos), Ulaanbaatar, Mongolia is the coldest capital city in the world. And it’s also one of the most polluted. In this rapidly-developing city, particulate air pollution... Read More
Published on July 18, 2014
Normal vs. osteoporotic bone. Image source: WebMD When children and adolescents go in for their yearly check-ups, the term “osteoporosis” is rarely mentioned. But it turns out that signs of this adult disease can be seen in kids decades before symptoms appear.Generally... Read More
Published on July 11, 2014
After nearly a decade in post-secondary education, a select few continue on and commit to specialized research training after earning their PhD. These postdoctoral scholars, commonly referred to as “postdocs", are training to become the leading researchers in their fields... Read More
Published on July 9, 2014
Photo by Anat Erdreich-Epstein, MD, PhD, from The Saban Research Institute of Children’s Hospital Los Angeles  In December 2013, Anat Erdreich-Epstein, MD, PhD, and colleagues were the first to link the level of RNA in the PID1 protein to brain tumor growth. Erdreich-... Read More
Published on July 3, 2014
Controlling our thoughts, actions and even our thoughts about our actions, the brain is an incredible powerhouse that shapes us into who we are. But its appearance and functions change as we grow up, making it important that researchers observe the brain during every stage of... Read More
Published on June 27, 2014
Have you seen the KCBS Los Angeles coverage on the special connection between Grace—a 4-year-old with a rare form of leukemia, and Ella—a bald, wig-wearing Barbie? If not, check it out!While Ella lifts her spirits day-to-day, Grace’s oncologist, Paul Gaynon, MD, from Children’... Read More
Published on June 25, 2014
Calling all Magic School Bus enthusiasts: Do remember when Arnold swallowed Ms. Frizzle and the rest of the class, giving them an “inside look” at the human body? Well, strap your bones right to your seat, because investigators from The Saban Research Institute are... Read More
Published on June 23, 2014
Between iPhone-toting 6 year olds and teenagers with online dating profiles, it seems as though kids are getting older, younger. But what if they actually are? Over the past 20 years, studies have shown that the rates of children starting puberty before ages 8 or 9 is on the... Read More
Published on June 18, 2014
Check out how biomedical engineer Tishya Wren, PhD, is using motion sensors to help kids with movement disorders at Children’s Hospital Los Angeles Read More
Published on June 5, 2014
Fibromyalgia tender points as outlined by the American College of Rheumatology. Credit:  Unseen by lab tests and the naked eye, fibromyalgia is an “invisible” condition characterized by chronic musculoskeletal pain and fatigue. Because there is no physical... Read More
Published on June 3, 2014
Credit: Larry Mulvehill. Photo Researchers, Inc.  It’s every parent’s worst nightmare: your child’s fever spikes, a cut keeps bleeding or body aches persist and you rush to the emergency department (ED). However, even though pediatric patients represent about 10 percent of... Read More
Published on May 27, 2014
X-ray image of inflamed bronchioles, characteristic of bronchiolitis. Image courtesy of Alex MacLennan, Royal Alexandra Hospital, United Kingdom.  A team of researchers, led by physicians from Children’s Hospital Los Angeles, have found that infants with bronchiolitis who were... Read More
Published on May 20, 2014
Midsagittal (left column) and axial (right column) views of the 3D airway. Courtesy of Yoon-Chul Kim, PhD, The Saban Research Institute of Children’s Hospital Los Angeles Snorting, gurgling and gasping for air are far cries from the peaceful sounds of a good night’s rest... Read More
Published on May 20, 2014
Photomicrograph of acute lymphoblastic leukemia (ALL) cells. Courtesy of Wellcome Images. Researchers at Children’s Hospital Los Angeles have discovered that by targeting a particular receptor, chemotherapy-resistant cancer cells can be killed in an acute form of childhood... Read More
Published on May 20, 2014
Smog rises from the ger districts on the outskirts of Ulaanbaatar, Mongolia. Courtesy of Lisa Gardner.  Burning coal for domestic heating may contribute to early fetal death according to a new study by experts from The Saban Research Institute of Children’s Hospital Los... Read More
Published on May 19, 2014
Respiratory system. Credit: Wei Shi, MD, PhD, from The Saban Research Institute of Children’s Hospital Los Angeles As part of the Developmental Biology and Regenerative Medicine Program, Wei Shi, MD, PhD, studies the molecular mechanisms of lung development, injury repair... Read More