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HIGH DOSE ERYTHROPOIETIN FOR ASPHYXIA AND ENCEPHALOPATHY (HEAL)

1) To determine if 5 doses of Epo (Erythropoietin) 1000 U/kg (birth weight) intravenous (IV) reduces the rate of death or neurodevelopmental impairment (mild, moderate, or severe) at 24 months of age. 

2) To assess safety of Epo. 

3) To determine whether Epo decreases the severity of HIE-induced brain injury as evidenced by early MRI and plasma biomarkers of brain injury.

Infant-Robot Interaction-CHLA

We are interested in observing whether and how infants learn when interacting with a robot during a learning assessment contingency paradigm. 

Longitudinal EEG and Sensors Study

Our goal is early identification of deviation from healthy brain development to allow targeted early intervention and improve developmental outcomes.

MR Imaging of Perinatal Brain Injury

The collection of the research data we hope will help better screening, diagnosing procedures and treatment of brain injury in newborns and identify a connection between MR imaging and neurodevelopmental outcomes.

Prader-Willi Syndrome (PWS)

This research is being done to test the safety and effectiveness of intranasal carbetocin to treat Prader Willi Syndrome.

Tumor Registry

The primary aim of this registry will be to identify genes and/or biologic and environmental factors that either cause these tumors or increase one's risk for developing them. Ultimately, research using this registry may result in improved diagnosis, more effective treatments and possibly prevention.