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Gut microbiome and response to oral typhoid vaccine

We are studying the role of gut microbiome diversity on the mucosal and systemic responses to Ty21a vaccine. This is to determine if a given microbiota composition is associated with specific immune responses and to evaluate the impact of an oral typhoid vaccination on the human gut microbiota.

HBCD (HEALthy Brain and Child Development)

To understand how environmental factors affect a child's early brain development. This includes positive factors like social support and parent-child bonding and challenges like poverty, stress and early life exposures.

Healthy Development

Determine how potentially stressful situations, including prematurity, hospitalizations, maternal mental health and rapid repeat births can impact a baby’s development in the first 12 months of their life.

Hybrid Closed Loop (HYCLO)

To evaluate how the Medtronic 670G closed loop system impacts clinical and patient-reported outcomes in individuals with type 1 diabetes.

Impact of the Pandemic on Families

The purpose of this study is to understand the impact of the COVID-19 pandemic on vulnerable families in Los Angeles, including those caring for a child with special health care needs. Information from this research will be used to understand what the key resource and service needs of families are at this time as well as identify interventions that can be developed or adapted to address these needs.

ImproveCareNow (ICN)

To improve patient care and achieve the best health outcomes possible for children with IBD.

Infant-Robot Interaction-CHLA

We are interested in observing whether and how infants learn when interacting with a robot during a learning assessment contingency paradigm. 

Influenza Breastfeeding Study

The effect of flu immunization on the level of immunity against the flu in breastmilk, and how this may help protect a breastfeeding infant.