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The objective of this study is to better understand how a single ventricular heart with Fontan physiology may affect brain health.

Develop better ways of screening and diagnosing certain types of brain injuries in infants and children who are born with and without congenital heart disease.

To evaluate how the Medtronic 670G closed loop system impacts clinical and patient-reported outcomes in individuals with type 1 diabetes.

To better understand the effects of breastfeeding on infant growth and development.

The collection of the research data we hope will help better screening, diagnosing procedures and treatment of brain injury in newborns and identify a connection between MR imaging and neurodevelopmental outcomes.

1. To identify family members of people with type 1 diabetes that may be at risk for developing type 1 diabetes. 2. To monitor the metabolic and immunologic status of at-risk individuals. Eligible individuals will be offered enrollment in type 1 diabetes prevention studies. See website for more details https://www.trialnet.org/

To better understand the effects of nutrition in early pregnancy on infant growth and development.

The objective of this study is to better understand the effects of chronic diseases, such as congenital heart disease, on blood vessel function and on blood characteristics.