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HIGH DOSE ERYTHROPOIETIN FOR ASPHYXIA AND ENCEPHALOPATHY (HEAL)

1) To determine if 5 doses of Epo (Erythropoietin) 1000 U/kg (birth weight) intravenous (IV) reduces the rate of death or neurodevelopmental impairment (mild, moderate, or severe) at 24 months of age. 

2) To assess safety of Epo. 

3) To determine whether Epo decreases the severity of HIE-induced brain injury as evidenced by early MRI and plasma biomarkers of brain injury.

Infant-Robot Interaction-CHLA

We are interested in observing whether and how infants learn when interacting with a robot during a learning assessment contingency paradigm. 

Influenza Breastfeeding Study

The effect of flu immunization on the level of immunity against the flu in breastmilk, and how this may help protect a breastfeeding infant.

Longitudinal EEG and Sensors Study

Our goal is early identification of deviation from healthy brain development to allow targeted early intervention and improve developmental outcomes.

Mother's Milk Study

To better understand the effects of breastfeeding on infant growth and development.

MR Imaging of Perinatal Brain Injury

The collection of the research data we hope will help better screening, diagnosing procedures and treatment of brain injury in newborns and identify a connection between MR imaging and neurodevelopmental outcomes.

MRI of placental function

Develop non-invasive measures to identify abnormal placental function in babies with and without congenital anomalies.