The objective of this study is to learn how anemia may affect oxygen delivery to the brain as measured by magnetic resonance imaging (MRI). By studying this, we hope to better identify people who may benefit from correction of their anemia.
The objective of this study is to better understand how a single ventricular heart with Fontan physiology may affect brain health.
A study to look at how having chronic anemia impacts the brain.
To investigate bone health in cerebral palsy and the relationship between walking and bone health.
The purpose of the study is to learn about how to improve access to care during young adulthood and to assess if telehealth is an acceptable form of care.
A study of glomerular disease patients to better understand the causes of the disease, response to therapy, and disease progression.
This study is a randomized, double-blind, active-controlled, titrated, parallel arm, multicenter study. It will compare the efficacy, safety and tolerability of twice daily Chronocort with twice daily IRHC (Cortef®) over a randomized treatment period of up to 52 weeks in participants aged 16 years and over with known classic CAH due to 21-hydroxylase deficiency. The primary efficacy assessment of biochemical responder rate and the key secondary assessments of dose responder rate and mean total daily dose will be assessed after 52 weeks of randomized treatment.
Validate the use of respiratory inductance plethysmography (RIP) and esophageal manometry in diagnosing upper airway obstruction (UAO) in newborn infants.
Develop better ways of screening and diagnosing certain types of brain injuries in infants and children who are born with and without congenital heart disease.
To evaluate the impact of non-Newtonian behavior on hemodynamic efficiency in children and young adults who have undergone the Fontan procedure.
