The first Phase IIb clinical trial in Down syndrome regression disorder (DSRD). An open-label, randomized study comparing the safety and efficacy of lorazepam, intravenous immunoglobulin (IVIg) and the Janus Kinase inhibitor (JAK inhibitor), tofacitinib.
To find out the effects of ApoE4 on the Preterm Brain.
Develop better ways of screening and diagnosing certain types of brain injuries in infants and children who are born with and without congenital heart disease.
To understand how environmental factors affect a child's early brain development. This includes positive factors like social support and parent-child bonding and challenges like poverty, stress and early life exposures.
It is common for individuals to develop headaches after a lumbar puncture (LP) procedure. While LPs are frequently performed, little is known about the risk factors for headaches in pediatric populations. This study aims to address this gap in knowledge by evaluating the risks factors on headache incidence, duration, onset, psychological state, and impact on quality of life. This study also aims to examine health inequities.
1) To determine if 5 doses of Epo (Erythropoietin) 1000 U/kg (birth weight) intravenous (IV) reduces the rate of death or neurodevelopmental impairment (mild, moderate, or severe) at 24 months of age.
2) To assess safety of Epo.
3) To determine whether Epo decreases the severity of HIE-induced brain injury as evidenced by early MRI and plasma biomarkers of brain injury.
We are interested in observing whether and how infants learn when interacting with a robot during a learning assessment contingency paradigm.
Our goal is early identification of deviation from healthy brain development to allow targeted early intervention and improve developmental outcomes.
The collection of the research data we hope will help better screening, diagnosing procedures and treatment of brain injury in newborns and identify a connection between MR imaging and neurodevelopmental outcomes.
Our purpose is to look at the long-term neurodevelopmental outcomes of preterm neonatal brain abnormalities.
