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HIGH DOSE ERYTHROPOIETIN FOR ASPHYXIA AND ENCEPHALOPATHY (HEAL)

1) To determine if 5 doses of Epo (Erythropoietin) 1000 U/kg (birth weight) intravenous (IV) reduces the rate of death or neurodevelopmental impairment (mild, moderate, or severe) at 24 months of age. 

2) To assess safety of Epo. 

3) To determine whether Epo decreases the severity of HIE-induced brain injury as evidenced by early MRI and plasma biomarkers of brain injury.

Impact of the Pandemic on Families

The purpose of this study is to understand the impact of the COVID-19 pandemic on vulnerable families in Los Angeles, including those caring for a child with special health care needs. Information from this research will be used to understand what the key resource and service needs of families are at this time as well as identify interventions that can be developed or adapted to address these needs.

Infant-Robot Interaction-CHLA

We are interested in observing whether and how infants learn when interacting with a robot during a learning assessment contingency paradigm. 

Influenza Breastfeeding Study

The effect of flu immunization on the level of immunity against the flu in breastmilk, and how this may help protect a breastfeeding infant.

JASPER Early Intervention for Tuberous Sclerosis (JETS)

Two main purposes of the study: (1) to see if social communication of children with TSC can be improved with a short term behavioral intervention (JASPER) and (2) to see if these improvements remain long after the study, and whether they can be observed with electroencephalography (EEG).

Longitudinal EEG and Sensors Study

Our goal is early identification of deviation from healthy brain development to allow targeted early intervention and improve developmental outcomes.

MR Imaging of Perinatal Brain Injury

The collection of the research data we hope will help better screening, diagnosing procedures and treatment of brain injury in newborns and identify a connection between MR imaging and neurodevelopmental outcomes.

Ophthalmologic disorders and eye tracking in children with autism spectrum disorder (ASD)

We are conducting a research study about visual problems in children with Autism Spectrum Disorder (ASD). We believe that many children with autism may have undiagnosed eye problems because they cannot explain when they have trouble seeing and may not undergo routine eye exams. We hope to develop a method to screen for visual problems in using a new, non-invasive technology called eye tracking. We will use a camera to record your child’s eye movements as they watch video clips for 15-20 minutes.

Prader-Willi Syndrome (PWS)

This research is being done to test the safety and effectiveness of intranasal carbetocin to treat Prader Willi Syndrome.