Investigator; Hematology, Oncology and Blood and Marrow Transplantation
Attending Physician
Assistant Professor of Pediatrics, Keck School of Medicine of USC
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My research focuses on T-cell leukemia, which is a type of blood cancer that affects children and adults. Twenty percent of children and 50% of adults afflicted by T-cell leukemia do not survive, and new treatments are urgently needed for these patients. Leukemias arise due to errors during normal blood cell development. Our goal is to identify these errors that lead to the development of T-cell leukemia. The ultimate goal is to identify errors in leukemic cells that can be targeted for the development of new anti-leukemic treatments.

Clinical Interests

Leukemia

Education

Medical School: 

Seth G.S. Medical College, Mumbai, India, M.B.B.S.

Internship: 

King Edward Memorial Hospital, Mumbai, India

Residency: 

Senior House Officer, Pediatrics, Swansea NHS Trust, Swansea, United Kingdom

Department of Pediatrics, Women and Children's Hospital of Buffalo, Buffalo, New York

Fellowship: 

Pediatric Hematology-Oncology, Children’s Hospital Los Angeles, University of Southern California, Los Angeles, CA

Accomplishments

Certification: 

ECFMG, 2004      

American Board of Pediatrics, 2007  

American Board of Pediatric Hematology Oncology, 2011

Professional Memberships: 

American Society of Hematology

Awards: 

The Society for Hematology and Stem Cells Travel Grant, 2010.

Winner of the 13th Indian Academy of Pediatrics Quiz (national level), The Indian Academy of Pediatrics National Conference, Patna, India, February 10, 2001.
Second Position at the student workshop on human genetics, The Indian Council of Medical Research, July 23 2002.

Dr. Moolgavkar Gold Medal for standing first in Surgery at the Final M.B.B.S university exams, October 2001.

Dr. Shirwalkar General Proficiency scholarship for standing first in anatomy, physiology and biochemistry, Dr. Shirwalkar competitive exam, 1998.

Winner of the Dr. Paranjpe Memorial Intercollegiate Pharmacology Quiz, G.S. Medical College, October 1999.

Honors in the M.B.B.S exams (Mumbai University, India) in Surgery, Preventive Medicine, Pharmacology, Pathology, Microbiology, Anatomy, Physiology and Biochemistry

Publications: 

Parekh C, Gaynon PS, Abdel-Azim H. End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia. Pediatric Blood and Cancer, 2015 May 14. doi: 10.1002/pbc.25582. [Epub ahead of print] PMID: 25976383

Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, Zhu Y, Parekh C, Balamurugan A, Yang OO, Crooks GM. Engineering the human thymic microenvironment to support thymopoiesis in vivo. Stem Cells, May 2014. PMID: 24801626

Kim WS, Zhu Y, Deng Q, Chin CJ, He CB, Grieco AJ, Dravid GG, Parekh C, Hollis RP, Lane TF, Bouhassira EE, Kohn DB, Crooks GM. Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem Cells, Feb 2014. PMID: 246776521.

Corselli M, Chin CJ, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L, Crooks GM, Péault B. Perivascular support of human hematopoietic stem/ progenitor cells. Blood 11;121(15):2891-901, April 2013. PMID: 234120951.

Parekh C, Crooks GM. Critical Differences in Hematopoiesis and Lymphoid Development between Humans and Mice. J Clin Immunol, 33(4):711-5, May 2013. PMID: 23274800

Research Interests: 

Our research focuses on T-cell leukemia, which is a type of blood cancer that affects children and adults. Twenty percent of children and 50% of adults afflicted by T-cell leukemia do not survive, and new treatments are urgently needed for these patients. Leukemias arise due to errors during normal blood cell development. Our goal is to identify these errors that lead to the development of T-cell leukemia. The ultimate goal is to identify errors in leukemic cells that can be targeted for the development of new anti-leukemic treatments.

Visit the Parekh Laboratory.

 

4650 Sunset Blvd.
Hematology/Oncology, MS #54
Los Angeles, CA 90027
Phone: 323-361-4624Office
Fax: 323-361-7128Fax