Attending Physician
Investigator, Ophthalmology Research and Neuroscience Research
Assistant Professor of Ophthalmology, Keck School of Medicine of USC
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As a surgeon specializing in retinal disorders of childhood and adolescence, Dr. Aaron Nagiel joins The Vision Center with a commitment to providing the highest quality care in a compassionate manner to his patients and their families. He complements this clinical expertise with an active laboratory and translational research program that is developing novel therapeutic approaches for children with diseases of the retina and vitreous.

Dr. Aaron Nagiel earned his bachelor’s degree from Harvard University summa cum laude, and then underwent combined MD and PhD training at Cornell University and The Rockefeller University in New York City. His PhD work was supported by an NIH fellowship and contributed to our understanding of how synapses form in the developing brain. After an internship at Memorial Sloan-Kettering Cancer Center, Dr. Nagiel completed both ophthalmology residency and vitreoretinal fellowship at the renowned Stein Eye Institute at UCLA. Dr. Nagiel is a member of the USC Neuroscience Graduate Program.  

He leads an active research program aimed towards developing better ways to treat pediatric retinal diseases through state-of-the-art imaging, advanced surgical devices, and novel treatments including gene therapy and stem cell-based therapy. He has authored two book chapters on the therapeutic use of stem cells for retinal disease and published numerous peer-reviewed journal articles. Dr. Nagiel serves as a reviewer for major ophthalmology journals and an editor of the textbook Cellular Therapies for Retinal Disease: A Strategic Approach. He is a recipient of the prestigious Heed Ophthalmic Foundation Fellowship and the Ronald G. Michels Fellowship Foundation Award, as well as numerous departmental awards during his time at UCLA including the Robert E. Christensen Research Award, the Pepose-Saltzman Young Investigator Award, and Excellence in Research Awards.

Clinical Interests

Dr. Nagiel specializes in the medical and surgical management of retinal diseases, including retinopathy of prematurity, retinal detachment, ocular trauma, familial exudative vitreoretinopathy, Coats disease, Norrie disease, X-linked retinoschisis, retinitis pigmentosa, Leber congenital amaurosis, Stickler syndrome, persistent fetal vasculature, and other pediatric retinal disorders.

Education

Medical School: 

Weill Cornell Medical College (MD)
The Rockefeller University (PhD)

Internship: 

Memorial Sloan-Kettering Cancer Center

Residency: 

Stein Eye Institute/ UCLA

Fellowship: 

Stein Eye Institute/ UCLA

Accomplishments

Certification: 

American Board of Ophthalmology

Professional Memberships: 

American Academy of Ophthalmology
Association for Research in Vision and Ophthalmology

Awards: 

2013 Robert E. Christensen Research Award, Stein Eye Institute; 2014 ARVO National Eye Institute Travel Grant; 2014, 2016 Excellence in Research Award, Stein Eye Institute; 2014, 2015 Pepose-Saltzman Young Investigator ARVO Award, Stein Eye Institute; 2015 Heed Ophthalmic Foundation Fellowship; 2015 Society of Heed Fellows; 2016 Fostering Innovative Retina Stars of Tomorrow (FIRST) Fellowship; 2016 Ronald G. Michels Fellowship Foundation Award

Publications: 

Nagiel A, Espiritu MJ, Wong RK, Lee TC, Lauer AK, Chiang MF, Chan RV. (2012) Retinopathy of prematurity residency training. Ophthalmology. 119 (12): 2644-2645.

Nagiel A, Sadda SR, Sarraf D. (2015) A Promising Future for Optical Coherence Tomography Angiography. JAMA Ophthalmology. 133 (6): 629-30.

Nagiel A, Freund KB, Spaide RF, Munch IC, Larsen M, Sarraf D. (2013) Mechanism of retinal pigment epithelium tear formation following intravitreal anti-vascular endothelial growth factor therapy revealed by spectral-domain optical coherence tomography. American Journal of Ophthalmology. 156 (5): 981-988.

Nagiel A, Lalane RA, Sadda SR, Schwartz SD. (2016) Ultra-Widefield Fundus Imaging: A Review of Clinical Applications and Future Trends. Retina. 36 (4): 660-678.

Schwartz SD, Tan G, Hosseini H, Nagiel A. (2016) Subretinal transplantation of embryonic stem cell-derived retinal pigment epithelium for the treatment of macular degeneration: An assessment at 4 years. Investigative Ophthalmology & Visual Science. 57 (5): ORSFc1-9.

Research Interests: 

Dr. Nagiel leads an active clinical and translational research program aimed towards developing better ways to treat pediatric retinal diseases through state-of-the-art imaging, advanced surgical devices, and novel treatments including gene therapy and stem cell-based therapy. In addition, he conducts laboratory research on retinal development by growing human “mini-retinas” in vitro. The aim of this research is to provide insights into cellular differentiation and connectivity in the human retina and how this process goes awry in the disease state.

Visit the Nagiel Laboratory.

 

4650 Sunset Boulevard
MS #88
Los Angeles, CA 90027
Phone: 323-361-2347Office