Research Seminar: “A New Approach to the Treatment of Diabetes and Chronic Kidney Disease: The Fasting Mimicking Diet”
Presented by
Laura Perin, PhD
Assistant Professor of Urology
The Saban Research Institute, Children's Hospital Los Angeles
Keck School of Medicine, University of Southern California
Valentina Villani, PhD
Postdoctoral Research Fellow
The Saban Research Institute, Children's Hospital Los Angeles
Talk Summary:
Dietary interventions can be used in different disease settings as either a complementary approach to standard medical treatment to promote faster healing or as direct therapeutic treatment to help patients manage the disease. Diabetes (type 2 and type 1, T1D and T2D), diabetic nephropathies and chronic kidney diseases are affecting our population at a high rate increasing patient mortality and morbidity. We have demonstrated that a low-protein and low-sugar fasting mimicking diet (FMD) promotes the reprogramming of pancreatic cells to restore insulin generation in islets from T1D patients and reverse both T1D and T2D phenotypes in mouse models. Furthermore, our preliminary observation in a rat model of renal injury shows evidence that FMD restores physiological renal parameters decreasing levels of proteinuria in the urine and ameliorates renal morphology.
More Information:
Lunch will be provided to seminar guests; first come, first served.
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