This study is recruiting CHLA staff/employees/trainees to participate in a study assessing the efficacy of different types of video in teaching a surgical skill to novices. Participants will complete a survey and a medical training task, watch a video, and then repeat the medical training task in 2 weeks.
To test the effectiveness of an addiction-based weight loss intervention, embodied first as a smartphone app with telephone coaching (AppCoach) compared to (1) addiction model based weight-loss app alone (App) and (2) multi-disciplinary in-clinic weight loss intervention (Clinic) on weight outcomes of overweight and obese adolescents at 3, 6, 12 and 18 months post enrollment.
The purpose of this study is to evaluate a sensor that transmits intracranial pressure, cerebrospinal fluid flow, and makes sure the path of the catheter remains open.
The purpose of the study is to learn about how to improve access to care during young adulthood and to assess if telehealth is an acceptable form of care.
This study is a randomized, double-blind, active-controlled, titrated, parallel arm, multicenter study. It will compare the efficacy, safety and tolerability of twice daily Chronocort with twice daily IRHC (Cortef®) over a randomized treatment period of up to 52 weeks in participants aged 16 years and over with known classic CAH due to 21-hydroxylase deficiency. The primary efficacy assessment of biochemical responder rate and the key secondary assessments of dose responder rate and mean total daily dose will be assessed after 52 weeks of randomized treatment.
Validate the use of respiratory inductance plethysmography (RIP) and esophageal manometry in diagnosing upper airway obstruction (UAO) in newborn infants.
To investigate the connection between diet, genetics, and diseases in Hispanic / Latino youth.
1) To determine if 5 doses of Epo (Erythropoietin) 1000 U/kg (birth weight) intravenous (IV) reduces the rate of death or neurodevelopmental impairment (mild, moderate, or severe) at 24 months of age.
2) To assess safety of Epo.
3) To determine whether Epo decreases the severity of HIE-induced brain injury as evidenced by early MRI and plasma biomarkers of brain injury.
Two main purposes of the study: (1) to see if social communication of children with TSC can be improved with a short term behavioral intervention (JASPER) and (2) to see if these improvements remain long after the study, and whether they can be observed with electroencephalography (EEG).
To determine if a home visitation program for breastfeeding mothers affects the health of their babies.
