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An Addiction-Based Mobile Health Weight Loss Intervention With Coaching

To test the effectiveness of an addiction-based weight loss intervention, embodied first as a smartphone app with telephone coaching (AppCoach) compared to (1) addiction model based weight-loss app alone (App) and (2) multi-disciplinary in-clinic weight loss intervention (Clinic) on weight outcomes of overweight and obese adolescents at 3, 6, 12 and 18 months post enrollment.

CTC

The purpose of the study is to learn about how to improve access to care during young adulthood and to assess if telehealth is an acceptable form of care.

CTLA (Abatacept) Prevention (TN18)

Abatacept is given as an investigational study drug to relatives of someone with type 1 diabetes who have positive diabetes antibodies in an attempt to prevent or delay the onset of type 1 diabetes. See TrailNet.org website for more details.

Healthy Development

Determine how potentially stressful situations, including prematurity, hospitalizations, maternal mental health and rapid repeat births can impact a baby’s development in the first 12 months of their life.

Hybrid Closed Loop (HYCLO)

To evaluate how the Medtronic 670G closed loop system impacts clinical and patient-reported outcomes in individuals with type 1 diabetes.