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3D Video Use in Laparoscopic Training

This study is recruiting CHLA staff/employees/trainees to participate in a study assessing the efficacy of different types of video in teaching a surgical skill to novices. Participants will complete a survey and a medical training task, watch a video, and then repeat the medical training task in 2 weeks.

An Addiction-Based Mobile Health Weight Loss Intervention With Coaching

To test the effectiveness of an addiction-based weight loss intervention, embodied first as a smartphone app with telephone coaching (AppCoach) compared to (1) addiction model based weight-loss app alone (App) and (2) multi-disciplinary in-clinic weight loss intervention (Clinic) on weight outcomes of overweight and obese adolescents at 3, 6, 12 and 18 months post enrollment.

Burosumab

To collect information on the long-term effects of XLH on children and adults who have participated in burosumab clinical trials, adults and children who have not participated in burosumab clinical trials, and who may or may not have been treated with burosumab during the course of the study.

CTC

The purpose of the study is to learn about how to improve access to care during young adulthood and to assess if telehealth is an acceptable form of care.

DSRD Clinical Trial

The first Phase IIb clinical trial in Down syndrome regression disorder (DSRD). An open-label, randomized study comparing the safety and efficacy of lorazepam, intravenous immunoglobulin (IVIg) and the Janus Kinase inhibitor (JAK inhibitor), tofacitinib.

Extubation failure in newborn infants

Validate the use of respiratory inductance plethysmography (RIP) and esophageal manometry in diagnosing upper airway obstruction (UAO) in newborn infants.

Headache After Lumbar Puncture Study

It is common for individuals to develop headaches after a lumbar puncture (LP) procedure. While LPs are frequently performed, little is known about the risk factors for headaches in pediatric populations. This study aims to address this gap in knowledge by evaluating the risks factors on headache incidence, duration, onset, psychological state, and impact on quality of life. This study also aims to examine health inequities.