Pragmatic Pediatric Trial of Balanced vs. Normal Saline Fluid in Sepsis (PRoMPT BOLUS)
To find out which of two commonly used IV fluids given in the Emergency Department for sepsis is most effective.
To find out which of two commonly used IV fluids given in the Emergency Department for sepsis is most effective.
Two main purposes of the study: To see if serious bacterial infections occur less than once a year in each study subject. This will determine if study drug is effective. Also to find out if study drug is safe and tolerable for study subjects.
To explore the safety and treatment effect of intravenous (IV) Remodulin as add on therapy in neonates with PPHN compared to placebo.
Study early development in infants who have an older sibling with autism.
To find out the effects of a chemical in Stevia on the symptoms of NAFLD.
To better understand the effects of nutrition in early pregnancy on infant growth and development.
To find out the effects of tenofovir alafenamide (TAF) on children and adolescents with chronic hepatitis B.
To evaluate the efficacy of tofacitinib based on remission in pediatric participants with moderately to severely active Ulcerative Colitis (UC).