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To see if eye tracking (ET) or electroencephalogram (EEG) assessments have potential use in future clinical trials of Autism Spectrum Disorders (ASD).

We want to learn more about how cancer treatment, such as immunotherapy (i.e., CAR T cell treatment), affects the brain, learning, and behavior in patients with Acute Lymphoblastic Leukemia (ALL).

The first Phase IIb clinical trial in Down syndrome regression disorder (DSRD). An open-label, randomized study comparing the safety and efficacy of lorazepam, intravenous immunoglobulin (IVIg) and the Janus Kinase inhibitor (JAK inhibitor), tofacitinib.

To better understand the genetic changes that make children susceptible to the development of autism spectrum disorder, and to study how these changes influence clinical outcomes.

Determine how potentially stressful situations, including prematurity, hospitalizations, maternal mental health and rapid repeat births can impact a baby’s development in the first 12 months of their life.

The purpose of this study is to understand the impact of the COVID-19 pandemic on vulnerable families in Los Angeles, including those caring for a child with special health care needs. Information from this research will be used to understand what the key resource and service needs of families are at this time as well as identify interventions that can be developed or adapted to address these needs.

Two main purposes of the study: (1) to see if social communication of children with TSC can be improved with a short term behavioral intervention (JASPER) and (2) to see if these improvements remain long after the study, and whether they can be observed with electroencephalography (EEG).

We are conducting a research study about visual problems in children with Autism Spectrum Disorder (ASD). We believe that many children with autism may have undiagnosed eye problems because they cannot explain when they have trouble seeing and may not undergo routine eye exams. We hope to develop a method to screen for visual problems in using a new, non-invasive technology called eye tracking. We will use a camera to record your child’s eye movements as they watch video clips for 15-20 minutes.

To test a new experimental drug Temisirolimus - Temsirolimus (also known as Torisel®) is approved for kidney cell cancer treatment in adults - in combination with approved chemotherapy drugs - in the hopes of finding a drug combination that may be effective against leukemia and non-hodgkin’s lymphoma that has come back after initial treatment. To find the highest dose that can be given without casing severe side effects.

This research is being done to test the safety and effectiveness of intranasal carbetocin to treat Prader Willi Syndrome.