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Team Clinic

The purpose of the study is to learn about how to improve access to care during adolescence/young adulthood and to see if Virtual Team Clinic is an acceptable form of care. Virtual Team Clinic is a new approach to provide care to (middle/high) school aged patients living with Type 1 Diabetes and their families. This new approach consists of Virtual Team Clinic appointments (primarily telemedicine, and/or in person as necessary). The study also incorporates group visits/medical appointments with a multidisciplinary care team (e.g., RD, RN, Social Worker, etc.). Each group will have a special theme and learning experience. You will learn how to better take care of your diabetes, get support from others, and hopefully have fun.

Telehealth Study

To explore the possibilities of providing weight management services to teenagers through technology.

Therapeutic Advances in Childhood Leukemia and Lymphoma Consortium (TACL) / Amgen Carfilzomib study

Carfilzomib (also known as Kyprolis®) is approved to be used in certain adult patients with relapsed or refractory multiple myeloma (myeloma that returns after a successful course of treatment or myeloma that does not respond to treatment). Multiple myeloma is a type of blood cancer. Carfilzomib is not approved to treat ALL. It has not been given in combination with the other drugs used in this study. This study is being done to find out if carfilzomib can be safely given before and during treatment with standard chemotherapy drugs.

Therapeutic Advances in Childhood Leukemia and Lymphoma Consortium (TACL) Marqibo® ALL study

This study aims to evaluate the side effects (good and bad) of giving Vincristine Suflate Liposome Infection (also known as Marqibo®) - a drug approved for leukemia treatment in adults but that is experimental in children - with other standard chemotherapy drugs and to measure how effective the combination is at treating children and young adults with leukemia that has come back after initial treatment.

Tumor Registry

The primary aim of this registry will be to identify genes and/or biologic and environmental factors that either cause these tumors or increase one's risk for developing them. Ultimately, research using this registry may result in improved diagnosis, more effective treatments and possibly prevention.

UCART19-Paediatric Acute Lymphoblastic Leukaemia (PALL) Study

CD19 is a B-cell surface protein expressed throughout B cell development; therefore, it is expressed on nearly all B cell malignancies, including acute lymphoblastic leukemia (ALL),and many non-Hodgkin lymphomas. B cell neoplasms are clonal tumors of mature and immature B lymphocytes (e.g., acute lymphoblastic leukemia).UCART19 is intended to treat CD19-positive B lymphoid malignancies in paediatric and adult populations.