CHLA Clinical Research Studies

Having volunteers participate in research studies and clinical trials is critical to our research efforts. Thousands of children and families are involved in our patient-centered studies every year. Many of the treatments used today are based on the results of past research studies and clinical trials conducted with our patients. Our scientific and clinical experts take the best ideas from the laboratory -- to the patient -- in the form of promising new treatments.

By searching our study directory, you may identify research that could impact the life of your child or of another child you know. Because the number of available research studies and clinical trials for children nationwide is small, every participant makes a significant contribution.

In addition to enrolling children with certain diseases in order to study treatments and prevention of those diseases, we also need to study healthy children. Ask your child’s doctor about volunteer study options that may be suitable for your child.

Please contact the study staff listed in your search results for more information.

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Study Details - ID: CHLA-17-00507
Health/Science/Disease Category:
Type 1 Diabetes (T1D)
Purpose of Research:
1. To identify family members of people with type 1 diabetes that may be at risk for developing type 1 diabetes. 2. To monitor the metabolic and immunologic status of at-risk individuals. Eligible individuals will be offered enrollment in type 1 diabetes prevention studies. See website for more details
Short Name:
PTP (TN01)
Full Title of Study:
Pathway to Prevention
Phase/Type of Study:
1. Be between 2.5 to 45 years and a sibling, offspring, or parent of an individual with type 1 diabetes. 2. Be between 2.5 to 20 years and a niece, nephew, aunt, uncle, grandchild, cousin, or half sibling of an individual with type 1 diabetes. 3. Those who are not family members and are known to have 1 or more islet antibodies are eligible for screening if needed to determine eligibility for a clinical trial to delay or prevent disease progression.
Time Commitment/Requirements:
Screening is offered annually for children under 18 or 1 time for adults. There is no compensation for screening. Individuals who are found to be at risk will be offered further testing 1 to 2 times per year with compensation provided.
Primary Investigator:
Roshanak Monzavi, MD
Coordinator Contact Name:
Dan Brimberry, PhD Debra Miller, BSN, CDE
Phone Number:
323-361-8641 323-361-5963
Clinical Trials .Gov Identifier: