CHLA Clinical Research Studies

Having volunteers participate in research studies and clinical trials is critical to our research efforts. Thousands of children and families are involved in our patient-centered studies every year. Many of the treatments used today are based on the results of past research studies and clinical trials conducted with our patients. Our scientific and clinical experts take the best ideas from the laboratory -- to the patient -- in the form of promising new treatments.

By searching our study directory, you may identify research that could impact the life of your child or of another child you know. Because the number of available research studies and clinical trials for children nationwide is small, every participant makes a significant contribution.

In addition to enrolling children with certain diseases in order to study treatments and prevention of those diseases, we also need to study healthy children. Ask your child’s doctor about volunteer study options that may be suitable for your child.

Please contact the study staff listed in your search results for more information.

Search by Keyword:    

Back to the full listing

Study Details - ID: CHLA-17-00323
Health/Science/Disease Category:
Premature Infants (Pre-term)
Purpose of Research:
Our purpose is to look at the long-term neurodevelopmental outcomes of preterm neonatal brain abnormalities.
Short Name:
Predicting the early childhood outcomes of preterm brain shape abnormalities
Full Title of Study:
Predicting the early childhood outcomes of preterm brain shape abnormalities
Phase/Type of Study:
Observational Study
Infants who were born prematurely, gestational age 21-36 weeks are eligible. English or Spanish speaking families only. PVL and grade I and II IVH will be considered. , Infants cannot participate in the study if they have a shunt, intubation, Cpap, Nasal Ventilation, chromosomal/genetic abnormalities, mitochondrial/metabolic diseases, treatment for extracorporeal membrane oxygenation (ECMO), or grade III/IV IVH.
Time Commitment/Requirements:
One neonatal MRI Scan, which can take anywhere from 30 minutes to an hour. At 9 months old and 18 months old your child will meet with a child developmental specialist, who will give them a developmental test. We anticipate that each visit will take approximately 3 hours total. Compensation for time and travel provided.
Primary Investigator:
Dr. Natasha Lepore
Coordinator Contact Name:
Emy Dacalos or Mike K. Gawad, BSc, CCRP
Phone Number:
323-361-7309 or (323) 361-3313
Email: or
Clinical Trials .Gov Identifier: