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The Saban Research Institute Annual Symposium highlights exciting strides that researchers at Children's Hospital Los Angeles and from around the globe are making in understanding the developmental origins of health and disease. Each year the theme of the event reflects an institutional research priority area.
"Health Complexities in Pediatrics: Systems in Action and Interaction" features research on the complex system of interactions and factors—from environmental to the cellular level—affecting children’s health, well-being and long-term outcomes. Learn more.
"Big Data-Big Impact" will explore how our capacity to rapidly collect and distribute substantial amounts of basic and clinical information through big data technology can be used to improve pediatric best practices, promote child health, and improve lifelong outcomes. Learn more.
"Models of Human Disease from the Laboratory to the Clinic" focused on the use of preclinical models—what works, what doesn’t, and why—to advance research on human diseases. Learn more.
“Global Impact of Pollution on Maternal and Child Health Across the Life Span,” focuses on how environmental factors affect children’s health as well as on the initiatives being implemented on a global level to help create a healthier future. Learn more.
“Toxic Stress, Resilience and Development,” featured presentations on the forefront of investigating the impact of chronic activation of a young child’s stress response system, so-called “toxic stress”. Distinguished thought leaders in research explored a wide range of inter-related topics, exploring toxic stress’s causes, its effects and the development of interventions to promote healthy physical and emotional growth and stability. Learn more.
“Metabolism, Immunity, Infection and Inflammation,” addressed the intimate links among these areas of study, their reciprocal interactions, and the balanced regulation required to fight disease and ensure optimal health. The symposium tackled topics ranging from the relationship between obesity and childhood cancer, to the cross-talk between cancer and immune cells within the tumor microenvironment; from strategies to improve immunization rates in the community setting, to interactions between intestinal microbiota and the immune system.
The pre-symposium evening reception featured a presentation by Martin Blaser, MD, director of the Human Microbiome Program at NYU Langone Medical Center. Learn more.
“Regenerative Medicine and Cellular Therapies: Inventing the Future for Children,” highlighted recent advances that hold great promise in many areas for improving child and adult health, including organ regeneration, stem cell-based therapy and tissue engineering. Researchers and clinicians presented cutting edge findings and David Warburton, MD, was honored as the holder of the inaugural Pasadena Guild Endowed Chair in Developmental Biology and Regenerative Medicine. Learn more.
“Developmental Origins of Health and Disease: The Developing Mind,” explored growing evidence that the earliest physical, environmental and emotional childhood experiences impact the developing brain and can have varied and lifelong effects on health. The Symposium convened a diverse group of nationally recognized experts and honored Cheryl Saban, PhD, Haim Saban and The Saban Family Foundation for a decade of building healthier futures through The Saban Research Institute. Learn more.
“Healthcare Transition: Empowering Our Patients to Become Healthy Adults,” focused on the process of supporting the needs of youth and families as they make the transition from pediatric to adult-oriented health systems. The Symposium honored Roberta Williams, MD, featuring the first annual Roberta G. Williams Lecture in Adolescent and Young Adult Transitional. Learn more.