Headshot of an older smiling man with dark skin tone and thinning greying hair wearing glasses and a shirt and tie underneath a blue suit jacket against a blurred outdoor background

T.S. Gunasekaran, MD, MRCP, FAAP

Director, Eosinophilic Gastrointestinal Diseases Program
Attending Physician
Clinical Professor of Pediatrics, Keck School of Medicine of USC

Dr. Gunasekaran, fondly known as "Dr. Guna," obtained his medical degree from Madras Medical College, University of Madras, India. Following this, he completed his internship and pediatric residency at the Institute of Child Health and Hospital for Children in Chennai, India, where he graduated at the top of his class. He furthered his pediatric expertise by undergoing additional training in the UK and achieving the prestigious MRCP, the highest postgraduate diploma in the UK.

Dedicating three years to fellowship training in pediatric gastroenterology at British Columbia Children’s Hospital, Vancouver, Canada, Dr. Gunasekaran made a significant impact in the field. His groundbreaking publication, "Efficacy and Safety of Omeprazole in Children with Severe GERD" in the Journal of Pediatrics (1993), catalyzed extensive research in GERD for years to come. This research substantially transformed the management of children with GERD, leading to a significant reduction in the need for surgery to treat the condition. This early work paved the way for his career in GERD and esophageal disorders.

Relocating to Chicago, Dr. Gunasekaran continued his research on GERD and similar medications to omeprazole and established himself as an expert in pediatric esophageal diseases. With that focused expertise in esophageal diseases, in 2007 he started the multi-disciplinary Eosinophilic Esophagitis Program in Chicago, which rapidly grew to serve 310 patients. His treatment focuses on a holistic approach to treating and actively managing this esophageal disorder.

Dr. Gunasekaran currently serves as full-time faculty at CHLA, practicing evidence-based medicine and involving parents and children, age-appropriate, in the decision-making for their healthcare. His extensive clinical expertise will now benefit children and adolescents with eosinophilic gastrointestinal diseases (EGID) of Los Angeles. His vision is to expand the EGID program at CHLA as a regional and a destination center.

Clinical Interests

Eosinophilic Gastrointestinal Diseases
Diseases of the esophagus


Medical School

Madras Medical College, University of Madras, India


Institute of Child Health and Hospital for Children, Chennai, India


Institute of Child Health and Hospital for Children, Chennai, India
Aberdeen Children’s Hospital and other affiliated hospitals in the UK


British Columbia Children's Hospital, Vancouver, BC, Canada; Pediatric Gastroenterology



American Board of Pediatrics
American Board of Pediatric Gastroenterology


North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHN)
American Gastroenterology Association (AGA)
Member of the Royal College of Physicians (UK)

Medical Awards

Best Out Going Student, MD (Pediatrics), University of Madras, Chennai, India
Top Doctors List, Chicago Magazine, 2014-2023
Castle Connolly Top Doctors, Pediatric Gastroenterology, 2010-2022



Kory V, Gunasekaran T, Husain K, et al. Risk Factors for Esophageal Strictures in Children and Adolescents with Eosinophilic Esophagitis. J Adv Pediatr Child Health. 2022; 5: 033-038.

Gunasekaran T, Kory V, Sonawane S, et al. Comprehensive Comparison of Dysphagia Predominant Eosinophilic Esophagitis: With and Without Food Impaction. SN Comprehensive Clinical Medicine. 2021;3:2134-2140

Gunasekaran T, Kory V, Schwartz A, Berman J. Esophageal Strictures in Pediatric Patients with Eosinophilic Esophagitis; Short Segment Stricture Vs. Narrow Caliber Esophagus. SF Hepatology Gastroenterology. 2020

Gunasekaran T, Chu C, Chennuri R, et al. Detailed Histologic Evaluation of Eosinophilic Esophagitis in Pediatric Patients Presenting with Dysphagia or Abdominal Pain and Comparison of the Histology between the Two Groups. Can J Gastroenterol Hepatol 2017. Article ID 3709254

Gunasekaran T, Prabhakar G, Schwartz A, et al. Eosinophilic Esophagitis in children and adolescents with abdominal Pain. Comparison with EoE-Dysphagia and Functional Abdominal Pain. Can J Gastroenterol Hepatol. 2016

Gunasekaran T, Berman J, Lim-Dunham J. Esophageal Perforation; An Uncommon Initial Manifestation of Eosinophilic Esophagitis. Int J Pediatr Adolesc Med. 2016

Ravi A, Gunasekaran T, Berman J. Continuous 48 Hour Wireless Esophageal pH Monitoring in Children: Comparison Between Days 1 and 2. J Pediatr Gastroenterol Nutr. 2016; 62: 87-89.

Winter H, Gunasekaran T, Tolia V, Gottrand F, Barker PN, Illueca M. Esomeprazole for the treatment of gastroesophageal reflux disease in infants aged 1-11 Months: A Randomized Treatment-Withdrawal Study. J Pediatr Gastroenterol Nutr. 2012; 55:14-20.

Gunasekaran T, Hassall E. Efficacy and safety of omeprazole for severe gastroesophageal reflux in children. J Pediatr. 1993; 123:148-54.


Research Summary

Dr. Gunasekaran's research has consistently centered on esophageal diseases. He has authored approximately 40 articles in peer-reviewed journals, with a primary emphasis on topics related the esophagus. He intends to leverage his fellowship training and his extensive clinical and research expertise in eosinophilic GI disorders to concentrate on clinical research at CHLA.

4650 Sunset Blvd.
Los Angeles, CA 90027
United States