Headshot of a balding man with light skin tone and glasses wearing a open collar dress shirt with a bookcase in the background

Nathan J. Robison, MD, MS

Attending Physician; Hematology, Oncology and Blood and Marrow Transplantation
Associate Professor of Clinical Pediatrics, Keck School of Medicine of USC

Nathan Robison, MD, MS, is an attending neuro-oncologist at Children's Hospital Los Angeles, and an Associate Professor of Clinical Pediatrics at the USC Keck School of Medicine. He currently serves as Medical Director of Inpatient Services and Director of Quality Assurance for the Cancer and Blood Disease Institute, as well as Chemotherapy Safety Officer for CHLA. His research interests including the use of molecular targeted therapy for low-grade gliomas and other childhood brain tumors.

Clinical Interests

Treatment of pediatric brain and spinal cord tumors; treatment of plexiform neurofibromas.

Education

Medical School

Keck School of Medicine of USC

Internship

Children's Hospital Los Angeles: Pediatrics

Residency

Children's Hospital Los Angeles: Pediatrics

Fellowship

Children's Hospital Los Angeles: Pediatric Hematology/Oncology
Dana-Farber Cancer Institute, Boston Children's Hospital: Pediatric Neuro-Oncology

Accomplishments

Certifications

Pediatrics and Pediatric Hematology/Oncology, American Board of Pediatrics

Professional Memberships

Chair
Neurofibrumatosis Clinical Trials Consortium Glioma Committee

Member
Pediatric Brain Tumor Consortium Steering, Scientific, New Agents, Low-Grade and High-Grade Glioma, and Toxicity Monitoring Committees
Response Assessment in Pedatric Neuro-Oncology (RAPNO) working group
International Pediatric Low-Grade Glioma Coalition

Publications

Robison NJ, Su JA, Fang MJ, Malvar J, Menteer J. Cardiac Function in Children and Young Adults Treated with MEK Inhibitors: A Retrospective Cohort Study. Pediatr Cardiol. 2022 Aug;43(6):1223-1228. PMID: 35233653

Weiss BD, Wolters PL, Plotkin SR, Widemann BC, Tonsgard JH, Blakely J, Allen JC, Schorry E, Korf B, Robison NJ, Goldman S, et al. NF106: A Neurofibromatosis Clinical Trials Consortium Phase 2 Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults with NF1-Related Plexiform Neurofibromas. Journal of Clinical Oncology. 2021 Mar 1;39(7):797-806. PMID: 33507822

Fangusaro J, Witt O, Hernáiz Driever P, Bag AK, de Blank P, Kadom N, Kilburn L, Lober RM, Robison NJ, Fisher MJ, et al. Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. Lancet Oncol. 2020 Jun;21(6):e305-e316. PMID: 32502457

Robison NJ, Yeo KK, Berliner AP, et al. Phase I Trial of Dasatinib, Lenalidomide, and Temozolomide in Children with Relapsed or Refractory Central Nervous System Tumors. J Neurooncol May;138(1):199-207, 2018. PMID: 29427149

Bandopadhayay P, Bergthold G, London WB, Goumnerova LC, Morales La Madrid A*, Marcus KJ, Guo D, Ullrich NJ, Robison NJ, Chi SN, Beroukhim R, Kieran MW, Manley PE. Long-Term Outcome of 4,040 Children Diagnosed with Pediatric Low-Grade Gliomas: An Analysis of the Surveillance Epidemiology and End Results (SEER) Database. Pediatr Blood Cancer 61(7):1173-9, 2014. PMID: 24482038

Robison NJ, Campigotto F, Chi SN, et al. A Phase II Trial of a Multi-Agent Oral Antiangiogenic (Metronomic) Regimen in Children with Recurrent or Progressive Cancer. Pediatr Blood Cancer 61(4):636-42, 2014. PMID: 24123865

Robison NJ, Prabhu SP, Sun P, et al. Predictors of Neoplastic Disease in Children with Isolated Pituitary Stalk Thickening. Pediatr Blood Cancer 60(10):1630-5, 2013. PMID: 23670879

Research

  • Molecular targeted therapy for pediatric brain tumors
  • MEK inhibition
  • Pediatric low-grade glioma

Dr. Robison is interested in developing clinical trials that test new strategies in the treatment of children with brain tumors. His specific areas of interest are novel treatments targeting the tumor microenvironment, including antiangiogenic and immunomodulatory strategies; overcoming treatment resistance; treatment of diffuse pontine glioma and other poor prognosis brain tumors; treatment of low-grade glioma; neurofibromatosis.