Division Head of Medical Genetics
Co-director, Neurofibromatosis Clinic
Attending Physician
Associate Professor of Clinical Pediatrics, Keck School of Medicine of USC
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Linda M. Randolph, MD, FAAP, FACMG, is head of the Division of Medical Genetics at Children's Hospital Los Angeles. Dr. Randolph is assistant clinical professor of pediatrics at the Keck School of Medicine at the University of Southern California. She received her medical degree from George Washington University School of Medicine in Washington, D.C., then completed her residency at Children's National Medical Center in Pediatrics.

Her postgraduate fellowships were in clinical genetics at Harbor-UCLA Medical Center in Clinical Genetics and in clinical and molecular genetics at Cedars-Sinai Medical Center in Los Angeles.

Dr. Randolph holds membership in numerous professional societies, including the American Medical Association, American Society of Human Genetics, American College of Medical Genetics, American Academy of Pediatrics-Section on Genetics and Birth Defects, and Alpha Omega Alpha. Her research interests include dysmorphology (study of birth defects); prenatal genetics; clinical cytogenetics (study of the structure of chromosome material); the genetic disorder, phenylketonuria; and neurocutaneous disorders, which involve the nervous system and skin.

Dr. Randolph is widely published in leading medical journals. She is a recipient of the Blinder scholarship, as well as the National Foundation of Ileitis and Colitis scholarship award for study of inflammatory bowel disease.

Education

Medical School: 

George Washington University School of Medicine

Internship: 

Children's National Medical Center: Pediatrics

Residency: 

Children's National Medical Center: Pediatrics

Fellowship: 

Cedars Sinai Medical Center: Clinical and Molecular Genetics; Los Angeles County-Harbor/University of California Los Angeles Medical Center: Clinical Genetics

Accomplishments

Certification: 

Pediatrics: American Board of Pediatrics; Medical Genetics: American Board of Medicine Geneticsl; Clinical Cytogenetics: American Board of Medical Genetics

Professional Memberships: 

American Medical Association; American College of Medical Genetics; American Society of Human Genetics; Alpha Omega Alpha; American Academy of Pediatrics

Publications: 

Paquette L., Panigrahy A, Randolph L, Seri I. Isolated Fetal Microphthalmia Diagnosed by MRI Fetal Diagnosis and Therapy

Fetal Diagn Ther 2008

24:182-185.

Levy HL, Milanowski A, Chakrapani A, Cleary M, Lee P, Trefz FK, Whitley CB, Feillet F, Feigenbaum AS, Bebchuk JD, Christ-Schmidt H, Dorenbaum A, Randolph LM for the Sapropterin Research Group. A Phase III randomized placebo-controlled study of the efficacy of sapropterin dihydrochloride (tetrahydrobiopterin, 6R-BH4) in reducing phenylalanine levels in subjects with phenylketonuria. Lancet Vol. 370, Issue 9586, 11 August 2007, Pages 504-510.

Trefz F, Burton B, Longo N, Bebchuk J, Christ-Schmidt H, Martinez-Pardo Casanova M, Gruskin D, Dorenbaum A, Hennermann J, and the Sapropterin Research Group, including L.M. Randolph. Efficacy of sapropterin dihydrochloride in increasing phenylalanine tolerance in children with phenylketonuria: a Phase III, randomized, double-blind, placebo-controlled study. J Pediatr 2009

154:700-7.

Jackson, P.,Paquette, L., Watiker, V.,, Randolph, L., Ramanathan, R., Seri, I. Intrauterine Exposure to Mycophenolate Mofetil and Multiple Congenital Anomalies in a Newborn Infant: Possible Teratogenic Effect.. Am J Med Genet 2009

Part A 149A:1231-1236.

Barseghyan, K., Paquette, L.B., Randolph, L.M., Sklansky, M.S., Miller, D.A. Agenesis of the ductus venosus in a fetus with non-mosaic trisomy 22. Prenat Diagn. 2009 Sep

29(9):901-2.

Research Interests: 

Dysmorphology, Prenatal genetics, Neurofibromatosis, Autism. Research in progress includes: a Clinical Registry Related MPS VI Clinical Surveillance Program, Clinical Research Study entitled PKUDOS Registry.

4650 Sunset Blvd.
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Phone: 323-361-2178Office
Fax: 323-361-5937Fax

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