Jon Detterich, MD - Children's Hospital Los Angeles

Jon Detterich, MD

Attending Physician
Clinical Associate Professor of Pediatrics, Keck School of Medicine of USC

Jon A. Detterich, MD is an Assistant Professor of Pediatrics at the University of Southern California (USC) in the division of pediatric cardiology at Children’s Hospital Los Angeles with a subspecialty in non-invasive cardiac imaging, including fetal echocardiography. He graduated from the University of California, Irvine (UCI) with a Bachelors of Science in Biological Sciences in 1997, and then attended the Medical College of Wisconsin where he graduated in 2003. He completed his pediatric internship and residency at Children’s Hospital Los Angeles in 2006 and fellowship in pediatric cardiology at Children’s Hospital Los Angeles in 2009. He then completed a fourth year of subspecialty training and research in cardiac MRI and fetal echocardiography at Children’s Hospital Los Angeles while being supported by a scholar grant from the NHLBI.  Dr. Detterich is a board certified pediatrician since 2006 with subspecialty board certification in pediatric cardiology since 2010.

Dr. Detterich is involved in the detection and pre-term management of fetuses with congenital heart disease and in the post natal care of these patients in the clinic and further imaging of congenital heart lesions utilizing echocardiography and cardiac MRI. He is a representative of the Heart Institute at CHLA and an active member of  The Institute for Fetal Maternal Health (IMFH) at Hollywood Presbyterian Medical Center (HPMC) to care for fetuses diagnosed with major congenital malformations.

Clinical Interests

1. Pediatric cardiology, 2. Non-invasive imaging: cardiac MRI and fetal echocardiograph, 3. Cardiovascular disease in children and young adults with sickle cell anemia.


Medical School

Medical College of Wisconsin


Children's Hospital Los Angeles: General Pediatrics


Children's Hospital Los Angeles: General Pediatrics


Children's Hospital Los Angeles: Pediatric Cardiology; Subspecialty Training: Cardiac MRI and Fetal Echocardiography



Pediatrics: American Board of Pediatrics; Pediatric Cardiology, American Board of Pediatrics


American Academy of Pediatrics, American Heart Association, American College of Cardiology, The Society for Cardiac Magnetic Resonance.

Medical Awards

Fourth Year Medical Student Teaching Award, Medical College of Wisconsin, 2003; Pediatric Legislative Advocacy Award, Children’s Hospital Los Angeles, 2006; Travel Award, American Society of Hematology, 2007.

Specialty Interests




Jones, K., Tierney, K., Grubbs, B.H., Pruetz, J.D., Detterich, J. & Chmait, R.H. (2011). Fetoscopic Laser photocoagulation of feeding vessels to a large placental chorioangioma following fetal deterioration after amnioreduction. Fetal Diagnosis and Therapy, 31(3), 191-195.

Detterich, J., Noetzli, L., Dorey, F., Bar-Cohen, Y., Harmatz, P., Coates, T. & Wood, J. Electrocardiographic consequences of cardiac iron overload in thalassemia major. (2011). American Journal of Hematology, in press. PMCID: PMC3306475

Pruetz, J., Detterich, J., Trento, L. & Sklansky, M. (2011). Prenatal diagnosis of cor triatriatum sinister in association with hypoplastic left heart syndrome. Pediatric Cardiology, 32(6), 818-821.

Pruetz, J.D., Sklansky, M., Detterich, J., Korst, L.M., Llanes, A. & Chmait, R.H. (2011). Twin-twin transfusion syndrome treated with laser surgery: postnatal prevalence of congenital heart disease in surviving recipients and donors. Prenatal Diagnosis, 31(10), 973-977.

Sangkatumvong, S., Coates, T.D., Wood, J.C., Meiselman, H.J., Kato, R., Detterich, J.A., Bush, A. & Khoo, M.C. (2010). Time-varying analysis of autonomic control in response to spontaneous sighs in sickle cell anemia. Conference Proceedings: IEEE Engineering in Medicine and Biology Society, 2010,1626-1629.


Research Summary

In sickle cell disease, irregularly shaped cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to various parts of the body, impacting different organ systems.  Affected individuals with SCD can experience a wide variability of acute and chronic health problems leading to complications such as stroke, pulmonary hypertension, or organ damage to the kidneys, liver and spleen.

Jon Detterich, MD, looks at how the red blood cell is able to transport oxygen and other nutrients to specific organ systems. By studying the red blood cells of a patient using methods that allow researchers to watch blood flowing while also measuring how the heart and blood vessels are functioning, Detterich hopes to identify new approaches for delivering therapy to the red blood cell and vascular system of the very patient they are studying. The Detterich lab at CHLA is one of the first to focus on the nitric oxide that is produced within the red cells of patients with sickle cell disease.  His goal is to discover how this nitric oxide production interacts with the blood vessels, in all of the different organ systems, in order to guide new therapies that span all the disease variability.

Visit the Detterich Laboratory.

Research Studies

The objective of this study is to better understand the effects of chronic diseases, such as congenital heart disease, on blood vessel function and on blood characteristics.