CHLA Clinical Research Studies

Having volunteers participate in research studies and clinical trials is critical to our research efforts. Thousands of children and families are involved in our patient-centered studies every year. Many of the treatments used today are based on the results of past research studies and clinical trials conducted with our patients. Our scientific and clinical experts take the best ideas from the laboratory -- to the patient -- in the form of promising new treatments.

By searching our study directory, you may identify research that could impact the life of your child or of another child you know. Because the number of available research studies and clinical trials for children nationwide is small, every participant makes a significant contribution.

In addition to enrolling children with certain diseases in order to study treatments and prevention of those diseases, we also need to study healthy children. Ask your child’s doctor about volunteer study options that may be suitable for your child.

Please contact the study staff listed in your search results for more information.

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Study Details - ID: CHLA-19-00365
Health/Science/Disease Category:
PFIC
Short Name:
MRX-502 (MARCH PFIC)
Full Title of Study:
MRX-502: Randomized Double-blind Placebo-controlled Phase 3 Study to Evaluate the Efficacy and Safety of Maralixibat in the Treatment of Subjects with Progressive Familial Intrahepatic Cholestasis (PFIC) – MARCH-PFIC
Phase/Type of Study:
Phase 3
Purpose of Research:
To find out the effects of Maralixibat on the treatment of PFIC
Eligibility:
Children 1 to 18 years with diagnosis of PFIC with or without genetic testing
Time Commitment/Requirements:
27 weeks with 9 visits. Reimbursement for all expenses related to study participation provided.
Primary Investigator:
Chuan-Hao Lin, MD
Coordinator Contact Name:
Carly Weaver
Phone Number:
323-361-8631 or 774-258-0286
Email:
cweaver@chla.usc.edu
Clinical Trials .Gov Identifier:
NCT03905330