Acute Lymphoblastic Leukemia (ALL) |
Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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Acute Lymphoblastic Leukemia (ALL) (CAR T ALL) |
Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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Acute Lymphoblastic Leukemia (ALL) (Newly Diagnosed ALL) |
Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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ADHD-Attention Deficit Hyperactivity Disorder |
Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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Autistic Disorder, Constipation, Gastrointestinal Disease |
The Met Signaling System, Autism and Gastrointestinal Dysfunction |
Clinical Trials .Gov Identifier: NCT02442115 | Investigator: Dr. Levitt |
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Brain Development |
MR Imaging Perinatal Brain Injury: Fetal Substudy |
Investigator: Dr. Jodie Votava-Smith |
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Brain Tumor |
Treatment-related CNS Injury and Cerebral Blood Flow in Children with Posterior Fossa Brain Tumors |
Investigator: Mary Baron Nelson |
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Cardiology |
Advanced MR Imaging of Perinatal Brain Injury: Correlation with Neurocognitive Outcome |
Investigator: Dr. Ashok Panigrahy |
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Correlation of Neonatal Brain Imaging and Neurocognitive Assessment (Fetal Sub-study: Congenital Heart Disease patients and Control patients) |
Investigator: Dr. Jodie Votava-Smith |
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Cerebral Palsy |
Bone deficits and mechanical loading in ambulatory cerebral palsy |
Investigator: Tishya Wren, PhD |
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Chronic Anemia Syndromes (sickle cell disease and thalassemia) |
Cerebrovascular Reserve and White Matter Disease in Patients with Chronic Anemia |
Investigator: John Wood, MD |
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Congenital heart malformations |
Prospective, non-randomized, open label clinical study to assess the feasibility of the Bioabsorbable pulmonary valved conduit in subjects undergoing Right Ventricular Outflow Tract (RVOT) reconstruction |
Clinical Trials .Gov Identifier: NCT03022708 | Investigator: Cynthia Herrington, MD |
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COVID (SARS-CoV-2) |
DIVINCI : Dissection of Influenza Vaccination and Infection for Childhood Immunity |
Investigator: Dr. Pia Pannaraj |
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Household Exposure and Respiratory Virus Transmission and Immunity Study |
Investigator: Pia Pannaraj, MD |
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Crohn's Disease |
Safety of FMT in maintenance of pediatric Crohn's disease |
Clinical Trials .Gov Identifier: NCT03194529 | Investigator: Sonia Michail, MD |
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Eczema (AD) |
A PHASE 2/3 STUDY INVESTIGATING THE PHARMACOKINETICS, SAFETY, AND EFFICACY OF DUPILUMAB IN PATIENTS AGED ≥6 MONTHS TO <6 YEARS WITH SEVERE ATOPIC DERMATITIS |
Clinical Trials .Gov Identifier: NCT03346434 | Investigator: Peck Ong, MD |
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An Open-Label, Pilot Pharmacokinetic Study of INCB018424 Phosphate Cream in Pediatric Subjects With Atopic Dermatitis |
Investigator: Peck Ong, MD |
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Effect of Dupilumab (anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis - ATOPIC DERMATITIS RESEARCH NETWORK PROTOCOL-ADRN 09 |
Clinical Trials .Gov Identifier: NCT03389893 | Investigator: Peck Ong, MD |
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External Ventricular Drainage (EVD) |
Non-Invasive Validation of an Inegrated Multi-Sensor Platform for Quantitive Monitoring of Intracranial Pressure, Cerebrospinal Fluid Flow, and Ventricular Catheter Patency |
Investigator: Dr. Gordon J. McComb |
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Extubation failure in newborn infants |
A study of incidence of upper airway obstruction and other risk factors of extubation failure in newborn infants |
Investigator: Narayan Prabhu Iyer |
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GI / Pancreas |
Pediatric Longitudinal Cohort Study of Chronic Pancreatitis |
Clinical Trials .Gov Identifier: NCT03081182 | Investigator: Yuhua Zheng, MD |
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Glucocorticoid-Induced Osteoporosis (GIOP) |
A phase 3 randomized, double-blind, placebo-controlled, Parallel-group Study to evaluate the safety and efficacy of Denosumab / Prolia in Pediatric Subjects with Glucocorticoid-Induced Osteoporosis |
Clinical Trials .Gov Identifier: NCT03164928 | Investigator: Anna Ryabets-Lienhard, DO |
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Healthy Adults Planning to Receive the Ty21a Typhoid Vaccine |
Impact of the gut microbiome on response to oral typhoid vaccine in healthy adults |
Investigator: Dr. Pia Pannaraj |
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Healthy Controls |
Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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Healthy Mothers and their Healthy Infants Needed |
Characterization of the breast milk, infant oral and gut microbiomes in multiple geographic locations; role in immune development and response to oral rotavirus vaccine |
Investigator: Dr. Pia Pannaraj |
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Healthy Preterm Infants Needed |
A Phase 2b Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Preterm Infants |
Clinical Trials .Gov Identifier: NCT02878330 | Investigator: Dr. Pia Pannaraj |
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Healthy Subjects Needed |
(Cis-gender/Unrelated Controls) Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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(Healthy Controls) Assessment of Risk Factors for Injury in the Pediatric Athlete |
Investigator: Dr. Tishya Wren |
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(Healthy Controls) Brain blood flow and its response to changes to inhaled oxygen levels in subjects with and without sickle cell disease |
Investigator: Dr. John C. Wood |
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(Healthy Controls) Head Acceleration and Concussion Study |
Investigator: Dr. Bradley Peterson |
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(Healthy Controls) Neuroimaging: Emotions and Appetite Testing Study |
Investigator: Dr. Mimi Kim |
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(Healthy Fetus) Correlation of Neonatal Brain Imaging and Neurocognitive Assessment (Fetal Sub-study: Congenital Heart Disease patients and Control patients) |
Investigator: Dr. Jodie Votava-Smith |
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(Healthy Pregnancy) Characterizing placental function in utero using MR imaging |
Investigator: Dr. Vidya Rajagopalan |
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(Healthy Volunteers) Precision Medicine: All of Us Research Program |
Clinical Trials .Gov Identifier: Please visit this website to learn more about the study: https://allofus.nih.gov/ | Investigator: Daniella Meeker, PhD - USC Department of Preventive Medicine |
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Healthy Subjects Needed (Healthy Pregnancy) |
The Sweet PEA Study: a pilot study of the impact of diet during pregnancy on maternal and infant metabolic health |
Investigator: Michael I Goran, PhD |
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Hepatitis B |
A Randomized, Double-Blind Evaluation of the Pharmacokinetics, Safety, and Antiviral Efficacy of Tenofovir Alafenamide (TAF) in Adolescents with Chronic Hepatitis B Virus Infection (GS-US-320-1092) |
Clinical Trials .Gov Identifier: NCT02932150 | Investigator: Chuan-Hao Lin, MD |
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Hypoplastic Left Heart Syndrome |
Phase I safety of autologous umbilical cord blood derived mononuclear cells during surgical Stage II palliation of Hypoplastic Left Heart Syndrome |
Investigator: Ram Kumar Subramanyan, MD |
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hypoxic-ischemic encephalopathy (HIE) |
HIGH DOSE ERYTHROPOIETIN FOR ASPHYXIA AND ENCEPHALOPATHY A randomized, placebo-controlled, double-masked 500 - subject clinical trial of erythropoietin for the treatment of neonatal hypoxic-ischemic encephalopathy (HIE) |
Clinical Trials .Gov Identifier: NCT02811263 | Investigator: Tai-Wei Wu |
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IBD |
A Long-Term Non-Interventional Registry to Assess Safety and Effectiveness of Humira® (Adalimumab) in Pediatric Patients with Moderately to Severely Active Crohn's Disease (CD) |
Investigator: Hillel Naon, M.D |
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ImproveCareNow |
Investigator: Hillel Naon, M.D |
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Infant Development |
Home intervention for reducing sugary drinks and obesity in Hispanic women-infants. |
Clinical Trials .Gov Identifier: NCT03141346 | Investigator: Michael I Goran, PhD |
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Mother’s Milk: Determining the Impact of Human Milk Oligosaccharides (HMOs) on Healthy Infant Growth and Development. |
Investigator: Michael I Goran, PhD |
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Research Network on Stress and Health |
Investigator: Dr. Levitt |
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Using movement to measure early brain development |
Investigator: Beth Smith, PT, DPT, PhD |
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Infant MRI / Alzheimer's |
Effects of Genetic and Gestational Risk Factors for Late Onset Alzheimer's Disease on the Neonatal Brain Morphology |
Clinical Trials .Gov Identifier: N/A | Investigator: Natasha Lepore, PHD |
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Influenza virus (ID) |
Influenza vaccinations during breastfeeding: Analysis of immunological and virological responses in breast milk and among breastfed infants. |
Investigator: Pia Pannaraj, MD, MPH |
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NAFLD |
Super HEROES: Searching How the Extract Rebaudiosode Occludes Excess Steatosis |
Clinical Trials .Gov Identifier: NCT03985020 | Investigator: Tania Mitsinikos, MD |
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Nephrotic Syndrome |
Cure Glomerulonephropathy |
Investigator: Dr. Kevin Lemley |
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Nephrotic Syndrome Study Network |
Clinical Trials .Gov Identifier: NCT01209000 | Investigator: Dr. Kevin Lemley |
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Obesity |
An Addiction Model Based Mobile Health Weight Loss Intervention With Coaching in Adolescents With Overweight and Obesity: Multi-Site Randomized Controlled Trial |
Clinical Trials .Gov Identifier: NCT03500835 | Investigator: Alaina Vidmar, MD |
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Diets Based on PNPLA3 Genotype for Reducing Liver Fat in Hispanics with Pediatric non-alcoholic fatty liver disease |
Clinical Trials .Gov Identifier: NCT02948647 | Investigator: Michael I Goran, PhD |
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Neuroimaging: Emotions and Appetite Testing Study |
Investigator: Dr. Mimi Kim |
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Oncology |
CHLA Tumor Registry |
Investigator: Dr. Shahab Asgharzadeh |
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Pain / Anxiety |
Robots using empathy to reduce pain associated with IV insertion |
Clinical Trials .Gov Identifier: NCT02840942 | Investigator: Dr. Margaret Trost |
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Pain Management |
Adolescent Postoperative Longitudinal Study (APOLO) |
Investigator: Dr. Lorraine Kelley-Quon |
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PFIC |
MRX-502: Randomized Double-blind Placebo-controlled Phase 3 Study to Evaluate the Efficacy and Safety of Maralixibat in the Treatment of Subjects with Progressive Familial Intrahepatic Cholestasis (PFIC) – MARCH-PFIC |
Clinical Trials .Gov Identifier: NCT03905330 | Investigator: Chuan-Hao Lin, MD |
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MRX-502: Randomized Double-blind Placebo-controlled Phase 3 Study to Evaluate the Efficacy and Safety of Maralixibat in the Treatment of Subjects with Progressive Familial Intrahepatic Cholestasis (PFIC) – MARCH-PFIC |
Clinical Trials .Gov Identifier: NCT03905330 | Investigator: Chuan-Hao Lin, MD |
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Prader-Willi-Syndrome (PWS) |
Phase 3, Randomized, Double-Blind, Placebo-Controlled, 8-week Clinical Study to Assess the Efficacy, Safety, and Tolerability, of Intranasal Carbetocin (LV-101) in Prader-Willi Syndrome (PWS) with Long Term Follow-Up: CARE-PWS |
Clinical Trials .Gov Identifier: NCT03649477 | Investigator: Alaina Vidmar, MD |
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Premature Infants (Pre-term) |
Predicting the early childhood outcomes of preterm brain shape abnormalities |
Clinical Trials .Gov Identifier: NCT03410810 | Investigator: Dr. Natasha Lepore |
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Primary Immune Deficiency Disorders (PIDD) |
A Phase 3, Multinational, Multicenter, Open-Label Study of the Safety, Tolerability, Efficacy, and Pharmacokinetics of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10% in Adults and Children with Primary Immunodeficiency Diseases |
Investigator: Dr. Joseph Church |
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Relapsed Acute Lymphoblastic Leukemia (ALL) |
T2012-002: A Pilot Study of Vincristine Sulfate Liposome Injection (Marqibo®) in Combination with UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults with Relapse of Acute Lymphoblastic Leukemia |
Clinical Trials .Gov Identifier: NCT02879643 | Investigator: Dr. Alan Wayne |
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Relapsed Acute Lymphoblastic Leukemia (ALL) and Non-Hodgkins Lymphoma (NHL) |
T2014-001: A Phase I Trial of Temsirolimus (CCI-779, Pfizer, Inc.) in Combination with Etoposide and Cyclophosphamide in Children with Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma |
Clinical Trials .Gov Identifier: NCT01614197 | Investigator: Dr. Paul S. Gaynon |
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Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL) |
20140106 (formerly CFZ008); Phase 1b Study of Carfilzomib in Combination with Induction Chemotherapy in Children with Relapsed or Refractory Acute Lymphoblastic Leukemia |
Clinical Trials .Gov Identifier: NCT02303821 | Investigator: Paul S. Gaynon, MD |
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Relapsed or Refractory Acute Myelogenous Leukemia (AML) |
T2016-003: Epigenetic Reprogramming in Relapse AML: A Phase 1 Study of Decitabine and Vorinostat Followed by Fludarabine, Cytarabine and G-CSF (FLAG) in Children and Young Adults with Relapsed/Refractory AML |
Clinical Trials .Gov Identifier: NCT03263936 | Investigator: Dr. Deepa Bhojwani |
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Sepsis/ Emergency Medicine |
PRagMatic Pediatric Trial of Balanced vs. normal Saline Fluid in Sepsis |
Clinical Trials .Gov Identifier: NCT04102371 | Investigator: Ara Festekjian, MD, MS |
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Sickle Cell Anemia |
Brain blood flow and its response to changes to inhaled oxygen levels in subjects with and without sickle cell disease |
Investigator: Dr. John C. Wood |
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Systemic Lupus Erythematosus (SLE) |
Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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TBI - Traumatic Brain Injuries |
Head Acceleration and Concussion Study |
Investigator: Dr. Bradley Peterson |
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Transgender/Gender Non-conforming |
Maturation, Infectibility, and Trauma Contributes to HIV Susceptibility in Adolescents |
Investigator: Dr. Johanna Olson-Kennedy |
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Mental Health and Medical Illness Effects on Brain, Cognition, and Behavior |
Investigator: Dr. Bradley Peterson |
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The Impact of Early Medical Treatment in Transgender Youth |
Investigator: Dr. Johanna Olson-Kennedy |
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Treatment of Persistent Pulmonary Hypertension of the Newborn (PPHN) |
Intravenous Remodulin (Treprostinil) as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn: A Randomized, Placebo-Controlled, Safety and Efficacy Study |
Clinical Trials .Gov Identifier: NCT02261883 | Investigator: Philippe Friedlich |
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Type 1 Diabetes (T1D) |
A Prospective, Randomized, Double-Blind Comparison of LY900014 to Humalog with and Open-Label Postprandial LY900014 Treatment Group in Children and Adolescents with Type 1 Diabetes |
Clinical Trials .Gov Identifier: NCT03740919 | Investigator: Roshanak Monzavi, MD |
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Adolescents and Young Adults with T1D Assessment in the Center for Endocrinology, Diabetes, and Metabolism |
Investigator: Dr. Jennifer Raymond |
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CoYoT1 to California |
Clinical Trials .Gov Identifier: NCT03793673 | Investigator: Jennifer Raymond, MD, MCR |
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CTLA-4 Ig (Abatacept) for Prevention of Abnormal Glucose Tolerance (AGT) and Diabetes in Relatives At-Risk for Type 1 Diabetes Mellitus (T1DM) |
Clinical Trials .Gov Identifier: NCT01773707 | Investigator: Roshanak Monzavi, MD |
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Family Communication about Type 1 Diabetes |
Investigator: Jennifer Raymond, MD |
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Hybrid Closed Loop Insulin Delivery System Data Collection |
Investigator: Roshanak Monzavi, MD |
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Hydroxychloroquine for Prevention of Abnormal Glucose Tolerance and Diabetes in Individuals At-Risk for Type 1 Diabetes Mellitus |
Clinical Trials .Gov Identifier: NCT03428945 | Investigator: Roshanak Monzavi, MD |
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Pathway to Prevention |
Clinical Trials .Gov Identifier: NCT00097292 | Investigator: Roshanak Monzavi, MD |
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Ulcerative Colitis |
The Effect of Therapeutic Fecal Transplant on the Gut Microbiome in Children with Ulcerative Colitis |
Clinical Trials .Gov Identifier: NCT02291523 | Investigator: Sonia Michail, MD |
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Weight Management |
Group Telehealth Weight Management Pilot |
Clinical Trials .Gov Identifier: NCT03508622 | Investigator: Claudia Borzutzky, MD |
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X-linked Hypophosphatemia |
X-linked Hypophosphatemia Disease Monitoring Program – (XLH-DMP) |
Clinical Trials .Gov Identifier: NCT03651505 | Investigator: Anna Ryabets-Lienhard, DO |
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