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Content related to Backstory: An 18-Year Journey From Idea to FDA-Approved Therapy

A female doctor with medium skin tone performs ear examination on a young girl with medium skin tone
Research and Breakthroughs

Will N-Acetylcysteine Be the Next Therapy to Prevent Cisplatin-Induced Hearing Loss?

July 24, 2023
A CHLA clinical trial finds that N-acetylcysteine may be a promising next-generation therapy to reduce the risk of cisplatin-induced hearing loss.
Read more
A mother sits behind her toddler son and adjusts his hearing aid.
Research and Breakthroughs

New Machine Learning Tool Predicts a Child’s Personal Risk for Cisplatin-Induced Hearing Loss

May 5, 2025
The machine learning model quantifies a child’s individual risk of developing permanent hearing loss from the chemotherapy drug cisplatin.
Read more
Young woman with long curly dark hair and medium skin smiles as she sits across from a doctor, whose face is not visible.
Research and Breakthroughs

Study Creates National Benchmark for Cancer Survivorship Care

August 13, 2024
A new survey endorses the value of cancer survivorship care but finds that many adult patients aren’t accessing it.
Read more
17-year-old Hunter sits in an outdoor courtyard wearing a black button down shirt.
Our Patients

Channeling Challenge Into Community: Hunter’s Story

September 10, 2024
Hunter never let his acute lymphoblastic leukemia diagnosis define him—but today, he proudly wears the title “survivor” in support of cancer research.
Read more
A female doctor with medium-dark skin tone sits in an exam room and speaks to a child sitting on a woman's lap. All are wearing masks.
Research and Breakthroughs

Regular Screening of Pediatric Cancer Patients May Help Improve Symptom Management

December 30, 2024
A multi-center clinical trial demonstrates how new reporting tools help symptom management and intervention for children receiving cancer treatment.
Read more
A child wearing a white headscarf with yellow and blue circles on it sits in a hospital bed, looking at the camera.
Research and Breakthroughs

Study Targets Cisplatin Resistance in Pediatric Germ Cell Tumors

August 13, 2024
A CHLA oncologist is leading new research to improve outcomes for children, adolescents and young adults with relapsed or treatment-resistant germ cell tumors.
Read more
A young patient wearing a tiger print hospital gown holds the hands of their care team.
Advice From Our Experts

Childhood Leukemia Isn’t What It Used to Be: Latest Treatments, Research, and Reasons to Hope

March 4, 2025
Facing a new diagnosis? A pediatric oncologist explains what the care journey looks like for acute lymphoblastic leukemia, the most common form of childhood cancer.
Read more
Young girl with medium skin tone and dark hair wearing purple top sits on lap of woman with medium skin tone and dark hair across from health care worker in doctor's office
Research and Breakthroughs

Five Questions Parents Should Ask Their Child’s Oncologist About Participating in a Clinical Trial

September 19, 2023
Five important questions that parents should ask about participating in a cancer clinical trial.
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Guy Young, MD smiles in his lab coat with stethoscope draped around his neck
Research and Breakthroughs

Study: A Novel Medication for the Most Difficult-to-Treat Hemophilia Patients

March 29, 2023
Study results are promising for an investigational drug to prevent bleeding in patients with a severe clotting disorder.
Read more

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