Christian Hochstim, MD, PhD

Christian Hochstim, MD, PhD

Attending Physician
Investigator, Developmental Biology and Regenerative Medicine
Assistant Professor of Clinical Otolaryngology, Keck School of Medicine of USC

Christian Hochstim completed a fellowship in pediatric otolaryngology at Stanford with broad training in a range of complex problems including airway reconstruction, aerodigestive disorders, surgical treatment of obstructive sleep apnea, and hearing loss and cochlear implantation.  He also completed a PhD in developmental biology at Caltech, and his current research focuses on stem cell and regenerative medicine based approaches to laryngeal and tracheal reconstruction and prevention of stenosis. 

Clinical Interests

Complex airway disorders, children with tracheostomy, stridor and noisy breathing,  drooling and aspiration, subglottic and tracheal stenosis, voice disorders, vocal cord paralysis, laryngomalacia, obstructive sleep apnea, hearing loss, cholesteatoma, head and neck masses and tumors


Medical School

USC Keck School of Medicine

Graduate School

California Institute of Technology (PhD)


USC Keck School of Medicine, Otolaryngology


USC Keck School of Medicine, Otolaryngology


Stanford University, Lucile Packard Children’s Hospital, Pediatric Otolaryngology



American Board of Otolaryngology

California Medical Board

Professional Memberships

American Academy of Otolaryngology-Head and Neck Surgery

American Medical Association


American Society of Pediatric Otolaryngology Meeting, First Place Poster – Basic Science, 2014

Cohen-Geller Award, Pediatric Otolaryngology, Children’s Hospital of Los Angeles, 2012

Mark S. Ehrenreich Prize - Medical Ethics, USC Keck School of Medicine, 2009


Selected Publications:   

Bacterial biofilms and increased bacterial counts are associated with airway stenosis. Mazhar K, Gunawardana M, Webster P, Hochstim C, Koempel J, Kokot N, Sinha U, Rice D, Baum M. Otolaryngol Head Neck Surg. 2014 May;150(5):834-40. doi: 10.1177/0194599814522765. Epub 2014 Feb 10.

A novel orthotopic mouse model of head and neck cancer and lymph node metastasis. Masood R, Hochstim C, Cervenka B, Zu S, Baniwal SK, Patel V, Kobielak A, Sinha UK. Oncogenesis. 2013 Sep 9;2:e68. doi: 10.1038/oncsis.2013.33.

Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition.  Sinha UK, Schorn VJ, Hochstim C, Chinn SB, Zhu S, Masood R. Head Neck. 2011 Feb;33(2):178-88. doi: 10.1002/hed.21418.

Biofilm detection with hematoxylin-eosin staining.  Hochstim CJ, Choi JY, Lowe D, Masood R, Rice DH. Arch Otolaryngol Head Neck Surg. 2010 May;136(5):453-6. doi: 10.1001/archoto.2010.62.

Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code.  Hochstim C, Deneen B, Lukaszewicz A, Zhou Q, Anderson DJ. Cell. 2008 May 2;133(3):510-22. doi: 10.1016/j.cell.2008.02.046.


Molecular mechanisms of laryngeal and tracheal stenosis formation, laryngeal and tracheal development, stem cells and laryngeal and tracheal regeneration