Astgik Petrosyan PhD

Astgik Petrosyan, PhD

Researcher, Children’s Hospital Los Angeles
Assistant Professor, Research Urology, Keck School of Medicine of USC

Dr. Astgik Petrosyan‘s laboratory focuses on understanding the role of the extracellular matrix in cancer and development. She has expertise in tissue engineering, regenerative medicine, renal development, cancer, and chip technology.

Education

Graduate School

University of Southern California, PhD, Development, Stem Cells, and Regenerative Medicine
University of Southern California, Graduate Certificate, Diploma in Innovation

Accomplishments

Memberships

American Society of Transplantation
International Society for Stem Cell Research
American Society of Nephrology
Tissue Engineering and Regenerative Medicine International Society

Medical Awards

Transplant Regenerative Medicine Committees of Practice (COP) Executive Committee Member at Large, American Society of Transplantation

Publications

Publications

Frank CN, Hou X, Petrosyan A, Villani V, Zhao R, Hansen JR, Clair G, Salem F, De Filippo RE, Cravedi P, Lemley KV, Perin L. Effect of disease progression on the podocyte cell cycle in Alport Syndrome. Kidney Int. 2022 Jan;101(1):106-118. PMID: 34562503.

Angeletti A, Cantarelli C, Petrosyan A, Andrighetto S, Budge K, D'Agati VD, Hartzell S, Malvi D, Donadei C, Thurman JM, Galešić-Ljubanović D, He JC, Xiao W, Campbell KN, Wong J, Fischman C, Manrique J, Zaza G, Fiaccadori E, La Manna G, Fribourg M, Leventhal J, Da Sacco S, Perin L, Heeger PS, Cravedi P. Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis. J Exp Med. 2020 Sep 7;217(9):e20191699. PMID: 32717081.

Petrosyan A, Cravedi P, Villani V, Angeletti A, Manrique J, Renieri A, De Filippo RE, Perin L, Da Sacco S. A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier. Nat Commun. 2019 Aug 13;10(1):3656. PMID: 31409793.

Petrosyan A, Zanusso I, Lavarreda-Pearce M, Leslie S, Sedrakyan S, De Filippo RE, Orlando G, Da Sacco S, Perin L. Decellularized Renal Matrix and Regenerative Medicine of the Kidney: A Different Point of View. Tissue Eng Part B Rev. 2016, Jun;22(3):183-92. PMID: 26653996.

Petrosyan A, Da Sacco S, Tripuraneni N, Kreuser U, Lavarreda-Pearce M, Tamburrini R, De Filippo RE, Orlando G, Cravedi P, Perin L. A step towards clinical application of acellular matrix: A clue from macrophage polarization. Matrix Biol. 2017 Jan;57-58:334-346 PMID: 27575985.

Peloso A, Petrosyan A, Da Sacco S, Booth C, Zambon JP, OʼBrien T, Aardema C, Robertson J, De Filippo RE, Soker S, Stratta RJ, Perin L, Orlando G. Renal Extracellular Matrix Scaffolds From Discarded Kidneys Maintain Glomerular Morphometry and Vascular Resilience and Retains Critical Growth Factors. Transplantation. 2015 Sep;99(9):1807-16. PMID: 26018349.

Da Sacco S, Lemley KV, Sedrakyan S, Zanusso I, Petrosyan A, Peti-Peterdi J, Burford J, De Filippo RE, Perin L. A novel source of cultured podocytes. PLoS One. 2013 Dec 12;8(12):e81812. PMID: 24349133.

Research

Research Summary

Stem Cells, Extracellular Matrix, Molecular Biology, Regenerative Medicine, Cancer, Glomerulus on a Chip, and Human Kidney Developmental Biology