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Content related to Chemotherapy and Hearing Loss: Until Now, an Unquantified Risk

Physician with dark skin tone examines ear of young patient with light skin tone
Press Release

Cisplatin and Hearing Loss: Until Now, an Unquantified Risk

February 12, 2021
Children’s Hospital Los Angeles leads largest ever multi-center study to characterize side effects of a common chemotherapy agent
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Research and Breakthroughs

FDA Approval Marks New Era for Preventing Cisplatin-Induced Hearing Loss

October 13, 2022
A CHLA oncologist led a pivotal clinical trial leading to the approval of the first drug to prevent cisplatin hearing loss in children.
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Research and Breakthroughs

Treatment Significantly Reduces Chemotherapy-Induced Hearing Loss in Children

December 6, 2016
Investigators from Children’s Hospital Los Angeles and 37 other Children’s Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing
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Research and Breakthroughs

Long-Term Neurocognitive Effects Linked to Chemotherapy-Induced Hearing Loss

November 9, 2015
Investigators at Children’s Hospital Los Angeles have found that chemotherapy-induced hearing loss may also contribute to long-term neurocognitive deficits in pediatric brain tumor survivors.
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Patient with medium skin tone and dark hair speaks to health care provider in white lab coat
Research and Breakthroughs

Understanding Cancer Survival in Adolescents and Young Adults

November 8, 2021
Researchers have been delving deeper to better understand long-term cancer survival and quality of life for adolescent and young adult patients.
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Work That Matters

Faculty Spotlight: Etan Orgel, MD, MS

March 22, 2022
The novel cancer drugs often grab the headlines. But Dr. Orgel's research has a different focus: making current treatments better—and less toxic.
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Two masked researchers wearing white lab coats in front of computer monitor in laboratory setting
Research and Breakthroughs

ResearCHLA 2021 Highlights

October 14, 2021
In the News - Awards and Honors - New Faces
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Research and Breakthroughs

Clinical and Histological Markers Predict Hepatoblastoma Prognosis

February 14, 2022
A new study reveals the value of using clinical and histological characteristics to optimize treatment for hepatoblastoma, a rare liver cancer in children.
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Cross section illustration of two femur bones comparing their bone density
Research and Breakthroughs

Bone Loss Associated With Leukemia Therapy Occurs Sooner Than Previously Thought

February 12, 2016
Patients with acute lymphoblastic leukemia are at increased risk for bone fractures due to bone loss resulting from treatment. This decrease in bone density (as illustrated here) can occur as soon as
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