Content related to Targeting Macrophages in IBD

Shedding epithelial cells in the intestine. Image courtesy of Mark R. Frey, PhD, The Saban Research Institute, Children’s Hospital Los Angeles. The lining of the intestine is the most rapidly-renewing

Inflammatory bowel disease, which includes Crohn’s disease and ulcerative colitis, affects more than 1.4 million Americans and is globally becoming more common. Current medication targets the chronic

A new study at Children’s Hospital Los Angeles outlines an important molecular pathway in the intestines that could improve IBD treatments

Mark Frey, PhD, an investigator at The Saban Research Institute of Children’s Hospital Los Angeles, studies how the intestines repair themselves after injury.

Investigators at Children’s Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome (SBS) using a novel zebrafish model and by

Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles have identified new findings about an immune cell – called a tumor-associated macrophage – that

Explaining the role of ErbB4 regulators in inflammatory bowel disease (IBD), Patricia Lozano exudes poise and confidence. In front of fellow interns, she reviews the causes of IBD and discusses how