Studying zebrafish, investigators at The Saban Research Institute and the Heart Institute of Children’s Hospital Los Angeles discovered a new source for cells that can develop into coronary vessels and have identified the signaling protein, a chemokine called CXCL12, which guides this process.
Parents of patients treated at Children’s Hospital Los Angeles can download a free app called ImageInbox on their smartphones, which allows them to receive imaging files or to request the files be sent directly to another caregiver. CHLA is the first clinical site to offer the app, which is now available for free to any patient.
Researchers found that the presence of a few remaining leukemia cells, called minimal residual disease (MRD), at the end of induction chemotherapy was not predictive of risk or outcome in children with T-cell acute lymphoblastic leukemia (ALL). This opens the possibility for patients with T-cell ALL who have MRD to achieve complete remission without undergoing intensified cancer treatments and their associated toxicities.