Regulatory Oversight Committees
Research activities undertaken at the institute must be conducted in accordance with strict ethical principles and in compliance with federal, state, and institutional regulations/policies. Applicable research projects may not be conducted without appropriate regulatory oversight review and approval.
Regulatory oversight committees are mandated to promote the ethical and responsible conduct of research and to ensure compliance with regulatory requirements relating to research involving but not limited to the following:
- Conflicts of interest
- Vertebrate animals
- Biological infectious agents
- Human Derived Materials
- Recombinant DNA
- Synthetic nucleic acid molecules
- Viral vectors
- Gene transfers
- Human subjects
- Radioactive materials and devices
- Stem cells
Conflicts of Interest in Research Committee (COIRC)
Minimizes potential bias; protects the interests of researchers and the Institute through the disclosure, review, and support of research.
Contact the Conflicts of Interest in Research Office at ConflictofInterest@chla.usc.edu
Institutional Animal Care and Use Committee (IACUC)
Oversees the Institute’s animal care and use program, facilities, and procedures; provides a framework for compliance with federal policies, guidelines, and principles for the use of animals in research.
Contact the IACUC Office at IACUC@chla.usc.edu
Institutional Biosafety Committee (IBC)
Per NIH guidelines reviews/approves research involving recombinant DNA and synthetic nucleic acid molecules; also reviews/approves research involving biohazard materials. Members of the public are welcome to attend scheduled IBC meetings.
Contact the IBC Office at IBC@chla.usc.edu
Institutional Review Board (IRB)
Provides a core protection for human research participants through advance and periodic review of the ethical acceptability of proposals for human research.
Contact the Human Subjects Protection Program (HSPP) Office at HSPP@chla.usc.edu
Radiation Safety Committee (RSC)
Regulates safe use of radioactive materials and radiation-producing devices in research to ensure compliance with federal, state, and local regulations.
Contact the Radiation Safety Office at Radsafetyoffice@chla.usc.edu
Stem Cell Research Oversight Committee (SCRO)
Responsible for the review/approval of research involving the use of human embryonic and pluripotent stem cells.
Contact the Stem Cell Research Oversight Office at SCRO@chla.usc.edu