Wednesday Research Seminar Series

The Saban Research Institute (TSRI) Research Seminar Series features presentations by outstanding experts on current basic, clinical and translational research topics. Faculty and trainees are encouraged to invite and host speakers. Seminars occur each Wednesday, September through June, from 12–1 p.m. in the first floor auditorium of The Saban Building, 4661 Sunset Blvd., Los Angeles. All seminars are open to the public and lunch is served to the first 70 attendees.

2018 - 2019 Wednesday Research Seminar Speakers

August 22, 2018
Beatrice Beebe, PhD, Clinical Professor of Medical Psychology (in Psychiatry), College of Physicians & Surgeons, Columbia University, New York State Psychiatric Institute; faculty at the Columbia Psychoanalytic Center, the Institute for the Psychoanalytic Study of Subjectivity, and the N.Y.U. Postdoctoral Program in Psychotherapy and Psychoanalysis; Topic: “Mother-infant microanalysis is a social microscope: Origins of disorganized attachment”; Hosted by Brad Peterson, MD

September 5, 2018
Meghan Azad, PhD, Canada Research Chair in Developmental Origins of Chronic Disease, Research Scientist, Children’s Hospital Research Institute of Manitoba, Assistant Professor, Pediatrics & Child Health, University of Manitoba; Topic: “Milk & Microbes: Breastfeeding, Gut Microbiota and the Developmental Origins of Chronic Disease in the CHILD cohort”; Hosted by Michael I. Goran, PhD

September 12, 2018
Mark Frey, PhD, Investigator, Gastroenterology, Hepatology and Nutrition, Associate Professor of Pediatrics, Keck School of Medicine of USC; Topic: “Neuregulins reduce intestinal inflammation through both epithelial and immune signaling”

October 10, 2018
Karen K Ryan, PhD, Associate Professor, Department of Neurobiology, Physiology and Behavior, University of California, Davis; Topic: “Control of Dietary Protein Intake by the Liver”; Hosted by Rohit Kohli, MBBS, MS

October 31, 2018
Christopher Del Vecchio, Director, Office of Technology Commercialization (OTC), The Saban Research Institute, Children’s Hospital Los Angeles & Omkar Kulkarni, Chief Innovation Officer, Children’s Hospital Los Angeles; Topic: “The Triple 'I': An Introduction to Intellectual Property, Inventions, and Innovation at CHLA”

November 7, 2018
Jodi S. Ogden, MBA, CRA, Vice President, Research Operations, The Saban Research Institute, Children’s Hospital Los Angeles; Topic: “Research Operations: Guiding Research Forward”

2017 - 2018 Wednesday Research Seminar Speakers

September 13, 2017
Pinchas Cohen, MD,  Dean, USC Leonard Davis School of Gerontology, University of Southern California. Topic: “Mitochondrial-Derived Peptides – Implications for Lifespan Health.” Hosted by Bradley Peterson, MD, Director, Institute for the Developing Mind, Interim Director, The Saban Research Institute, Children’s Hospital Los Angeles

October 25, 2017
Rupangi Vasavada, PhD, Associate Professor of Medicine, Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai. Topic: “Regeneration & Preservation of Pancreatic Beta Cells in Diabetes.” Hosted by Senta K. Georgia, PhD, Assistant Professor of Pediatrics, Division of Endocrinology, Developmental Biology & Regenerative Medicine Program, Saban Research Institute, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California

Novemver 8, 2018 - Discovery & Innovation Seminar
Leonard I. Zon, MD, Director, Stem Cell Program, Boston Children’s Hospital, Grousbeck Professor of Pediatrics, Harvard Medical School. Topic: “Pathways Regulating Hematopoietic Stem Cell Self-Renewal and Migration.” Hosted by Alan S. Wayne, MD, Director, Children's Center for Cancer and Blood Diseases, Head, Division of Hematology, Oncology and Blood & Marrow Tran splantation, Children's Hospital Los Angeles, Interim Director, USC Norris Comprehensive Cancer Center, Professor of Pediatrics and Medicine, Keck School of Medicine, University of Southern California

November 29, 2017 
Pei-Yi (Ivy) Lin, PhD, Assistant Professor of Pediatrics, Harvard Medical School. Topic: “NIRS and DCS: A Novel Bedside Tool for Assessing Cerebral Blood Flow and Metabolism in Infants.” Hosted by Tai-Wei Wu, MD from the Division of Neonatology, Assistant Professor of Clinical Pediatrics, USC Keck School of Medicine, Attending Neonatologist, Center for Fetal and Neonatal Medicine, Director of Neonatal Neurocritical Care, Newborn & Infant Critical Care Unit, Children’s Hospital Los Angeles 

Dec. 6, 2017
Maureen Su, MD, AM, Associate Professor of Pediatrics and Microbiology/Immunology, University of North Carolina School of Medicine. Topic: “Aire Expands: Lesson from APS1 and Beyond.” Hosted by Senta K. Georgia, Ph.D, Division of Endocrinology, Developmental Biology & Regenerative Medicine Program, Saban Research Institute, Children's Hospital Los Angeles, Assistant Professor of Pediatrics, Keck School of Medicine, University of Southern California

Dec. 13, 2017
John C. Gore, PhD, University Professor of of Radiology and Radiological Sciences, Biomedical Engineering, Physics and Astronomy, and Mole cular Physiology and Biophysics at Vanderbilt University Medical Center. Topic: “Some New Directions for Functional MRI.” Hosted by by Bradley Peterson, MD, Director, Institute for the Developing Mind, Interim Director, The Saban Research Institute, Children’s Hospital Los Angeles

Jan. 10, 2018
Kimberly Payne, PhD, Associate Professor of Pathology and Human Anatomy, Pediatrics and Medicine, Loma Linda University  Topic: “Cytokine Overdose: A Novel Paradigm for the Use of TSLP as a Biologic to Treat Ph-like B-ALL with Over Expression of CRLF2.” Hosted by Hisham Abdel-Azim, MD, MS, Associate Professor of Pediatrics, Children’s Center for Cancer and Blood Diseases, Director, Flow Cytometry/Sorting Lab, Co-Director, Stem Cell Processing Laboratory, Children’s Hospital Los Angeles, The Saban Research Institute, Keck School of Medicine, University of Southern California

Feb. 7, 2018
Rebecca Simmons, MD, Hallam Hurt Professor Pediatrics, Perelman School of Medicine, University of Pennsylvania, Children’s Hospital Philadelphia. Topic:
“The Yin and the Yang of inflammation in ß-cell dysfunction in IUGR.” Hosted by Sebastien G. Bouret, PhD, Associate Professor of Pediatrics, Developmental Neuroscience Program, Center for Endocrinology, Diabetes & Metabolism, Scientific Director | Animal Care Facility, Scientific Director | Rodent Metabolic Core, The Saban Research Institute, CHLA, Keck School of Medicine of USC

Feb. 14, 2018
Evan Deneris, PhD, Professor of Neurosciences, Case Western Reserve University, School of Medicine, Department of Neurosciences. Topic: "Gene Regulatory Networks Controlling Serotonergic Function Across the Lifespan." Hosted by Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics, Institute for the Developing Mind, Children's Hospital Los Angeles, WM Keck Provost Professor of Neurogenetics, Keck School of Medicine of USC

Feb. 19, 2018
Rebecca Simmons, MD, Hallam Hurt Professor Pediatrics, Perelman School of Medicine, University of Pennsylvania, Children’s Hospital Philadelphia. Topic: “The Yin and the Yang of inflammation in ß-cell dysfunction in IUGR.”  Hosted by Sebastien G. Bouret, PhD, Associate Professor of Pediatrics, Developmental Neuroscience Program, Center for Endocrinology, Diabetes & Metabolism, Scientific Director of the Animal Care Facility, Scientific Director of the Rodent Metabolic Core, The Saban Research Institute, Children’s Hospital of Los Angeles, Keck School of Medicine of USC

March 14, 2018  Floyd H. Gilles Lecture in Neuroscience Research
Daniel Geschwind, MD, PhD, Gordon and Virginia MacDonald Distinguished Professor in Human Genetics, Professor of Neurology and Psychiatry, Senior Associate Dean and Associate Vice Chancellor for Precision Health, Director, Center for Autism Research and Treatment, Semel Institute, UCLA. Topic: "Genetics and genomics of Autism Spectrum Disorder." Hosted by:  Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics, Institute for the Developing Mind, Children's Hospital Los Angeles, WM Keck Provost Professor of Neurogenetics, Keck School of Medicine of USC

March 21, 2018  Research Readiness Workshop
Tarek Azzam, PhD, Associate Professor & Chair of the Evaluation & Applied Methods PhD Program, Director of The Evaluators’ Institute (TEI), Claremont Graduate University. Topic: “Data Visualization for Knowledge Generation” 

March 28, 2018
Yutaka Yoshida, PhD, Associate Professor in Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center. Topic: "Understanding the neural circuits underlying locomotor and skilled motor behaviors in mammals."  Hosted by Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics, Institute for the Developing Mind, Children's Hospital Los Angeles, WM Keck Provost Professor of Neurogenetics, Keck School of Medicine of USC

April 18, 2018
Susan Lynch, PhD, Professor of Medicine, Director Colitis and Crohn's Disease, Microbiome Research Core, Department of Medicine, University of California San Francisco. Topic: “Canary in the Coal Mine: How the neonatal gut microbiome promotes atopy and asthma development in childhood.” Hosted by Allison Knoll, PhD, Assistant Professor of Research Pediatrics, Keck School of Medicine, University of Southern California

May 16, 2018
Marc P. Michalsky, MD, FACS, FAAP, Professor of Clinical Surgery and Pediatrics, Nationwide Children’s Hospital and The Ohio State University College of Medicine, Surgical Director – Center for Healthy Weight and Nutrition. Topic: “Adolescent Bariatric Surgery: Indications, Operations, Outcomes and Challenges.” Hosted by Rohit Kohli, MBBS, MS, FAASLD, Division Chief, Gastroenterology, Hepatology, and Nutrition, Children's Hospital Los Angeles, Associate Professor of Pediatrics (Clinical Scholar), Keck School of Medicine, University of Southern California

May 30, 2018
Daniel L. Marks MD, PhD, Professor, Pediatrics, Credit Unions for Kids, Professor of Pediatric Research, Director of Fellowship Research, Co-Director OHSU MD PhD Program, Oregon Health & Science University. Topic: “Mechanisms of Cachexia in Chronic Disease”

June 20, 2018
Julie Jaffray, MD, Attending Physician, Hematology, Oncology and Blood and Marrow Transplantation, Assistant Professor of Clinical Pediatrics, Keck School of Medicine of USC; Topic: “Prevention of Pediatrics Venous Thrombosis, a report from the Children’s Hospital Acquired Thrombosis Study”

June 27, 2018
Christian Hochstim, MD, PhD, Assistant Professor of Clinical Otolaryngology, Keck School of Medicine of USC, Director of Resident Rotation, Division of Otolaryngology, Co-Director Aerodigestive Program, Children’s Hospital Los Angeles, Investigator, Developmental Biology and Regenerative Medicine, The Saban Research Institute; Topic: “Tissue-engineering and the future of airway reconstruction"

2016 - 2017 Wednesday Research Seminar Speakers

Sept. 14, 2016
Dominic Abrams, MD, Director, Inherited Cardiac Arrhythmia Program, Boston Children's Hospital Assistant Professor, Harvard Medical School; Topic: “Developing Clinical Services for Families with Inherited Cardiovascular Disease”; Hosted by Allison Hill, MD

Sept. 28, 2016
Thomas Buchanan, MD, Professor of Medicine, Obstetrics and Gynecology, and Physiology and Biophysics, Vice Dean for Research, Director of Southern California Clinical and Translational Science Institute, Chief of Endocrinology and Diabetes, Keck School of Medicine of USC; Topic: “From Biology to Prevention – A Translational Science Story about Type 2 Diabetes”; Hosted by The George Donnell Society for Pediatric Scientists

Oct. 26, 2016
Thomas J. Mariani, PhD, Professor of Pediatrics and Environmental Medicine, Division of Neonatology, Director, Pediatric Molecular and Personalized Medicine Program, University of Rochester; Topic: “Molecular Characterization of the Human Infant Airway”; Hosted by Denise Al Alam, PhD

Nov. 9, 2016
Rose M. Viscardi, MD, Professor of Pediatrics and Medicine, University of Maryland School of Medicine; Topic: “Current Concepts of Ureaplasma spp. Respiratory Infection in Preterm Infants: Time to Treat?”; Hosted by Denise Al Alam, PhD

Nov. 16, 2016
Jerry J. Zimmerman, MD, PhD, Faculty, Pediatric Critical Care Medicine, Professor of Anesthesiology and Pediatrics, University of Washington School of Medicine; Topic: “Novel Host Gene Expression Signature for Diagnosing Sepsis”; Hosted by Christopher Newth, MD, FRCPC

Nov. 30, 2016
Jason Gleghorn, PhD, Assistant Professor, Department of Biomedical Engineering, University of Delaware; Topic: “Connecting Mechanical and Molecular Regulators of Lung Development”; Hosted by David Warburton, OBE, DSc, MD, MMM, FRCP, FRCS, FRCPCH

Dec. 6, 2016 - Floyd H. Gilles Lecture
Pasko Rakic, MD, PhD, Dorys McConnell Duberg, Professor of Neuroscience and Professor of Neurology, Yale School of Medicine; Topic: “Molecular and Cellular Mechanisms of Neuronal Migration”; Hosted by Marvin D. Nelson J.R., MD, MBA, FACR

Dec. 14, 2016 - Core Facility Seminar
Dr. Shahab Asgharzadeh, Dr. Jeffrey Bender, & Fan Li. Topic: “Learn About Resources Available to Support your Research with: The Single Cell, Sequencing and CyTOF - SC2 Core!”

Jan. 18, 2017 - Core Facility Seminar
Topic: "Learn About Resources Available to Support your Research with: Cellular Imaging Core & Flow Cytometry Core (FACS)"

Jan. 25, 2017
Mamata Sivagnanam, MD, Associate Professor of Pediatrics, Fellowship Director Pediatric Gastroenterology Fellowship, Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of California San Diego, Rady Children's Hospital San Diego; Topic: “Lessons from a Rare Disease: Genetics and Study of Intestinal Failure”; Hosted by Rohit Kohli MBBS, MS, Division Chief, Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles

Feb. 15, 2017
Ching-Ling (Ellen) Lien, PhD, Assistant Professor, Department of Surgery, Biochemistry and Molecular Medicine, University of Southern California, Children's Hospital Los Angeles; Topic: “Cardiovascular Development and Regeneration— Zebrafish, Neonatal Mouse and Beyond”; Hosted by David Warburton, OBE, DSc, MD, MMM, FRCP, FRCS, FRCPCH

Feb. 22, 2017
Bruce J Aronow, PhD, Endowed John J Hutton, M.D. Professor of Biomedical Informatics, Divisions of Biomedical Informatics, Developmental Biology, and Genetics, Cincinnati Children's Hospital Medical Center and by courtesy, Computer Science and Electrical Engineering, University of Cincinnati; Topic: “Systems-based Analysis of Multiomic Data to Improve Understanding of Development and Disease”; Hosted by David Warburton, OBE, DSc, MD, MMM, FRCP, FRCS, FRCPCH

Mar. 1, 2017
Franck Mauvais-Jarvis, MD, PhD, Director, Diabetes Discovery Research & Gender Medicine Laboratory, Section of Endocrinology, Price-Goldsmith Endowed Professorship in Nutrition Research, Professor, Department of Medicine and Pharmacology, Director, Tulane Diabetes Research Program; Topic: “Role of Estrogens in Islet Protection. Implications for Juvenile Diabetes”; Hosted by Senta K. Georgia, Ph.D

Mar. 8, 2017
Nabil Ahmed, MD, MPH, Associate Professor, Department of Pediatrics, Center for Cell and Gene Therapy, Baylor College of Medicine; Topic: “Pragmatic Development of T cell Therapies for Cancer”; Hosted by Hisham Abdel-Azim, MD, MS

Mar. 22, 2017
Tamara D. Simon, MD, MSPH, Associate Professor of Pediatrics, Department of Pediatrics, Divisions of Hospital Medicine and General Pediatrics, University of Washington and Seattle Children's Hospital, Associate Program Director, Health Services and Quality of Care Research Fellowship, Center for Clinical and Translational Research, Seattle Children's Research Institute; Topic: “Risk Factors for CSF Shunt Infection and Reinfection”; Hosted by Christopher J. Russell, MD

April 5, 2017
Xin Sun, PhD, Professor, Department of Pediatrics, University of California, San Diego School of Medicine; topic: “Mechanisms of Lung-Associated Congenital Disorders: Surprises from Mouse Models.”  Hosted by David Warburton, OBE, DSc, MD, MMM, FRCP, FRCS, FRCPCH, Director, Developmental Biology and Regenerative Medicine Program

April 12, 2017
Josh Rubin, MD, PhD, Professor of Pediatrics and Neuroscience, Co-Director, Pediatric Neuro-Oncology, St Louis Children's Hospital, Co-Leader, Solid Tumor Therapeutics Program, Alvin J. Siteman Cancer Center, Washington University School of Medicine. Topic: "What's Good for the Goose would have been Good for the Gander: Sex Differences in Brain Tumor Biology." Hosted by Hosted by Anat Erdreich-Epstein, MD, PhD

April 19, 2017
Robert Mecham, PhD, Alumni Endowed Professor of Cell Biology & Physiology, Professor of Medicine, Pediatrics, and Bioengineering, Washington University School of Medicine. Topic: “Diverse Roles of Extracellular Matrix in Tissue Development”.  Hosted by Wei Shi, MD, PhD, Associate Professor, Developmental Biology and Regenerative Medicine Program

April 26, 2017
Kenneth D. R. Setchell, PhD, Professor, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine. Topic: "What can be Learned from a Drop of Urine” Metabolomics at its Earliest - Discovery of Bile Acid Synthesis Disorders Translated to a Successful Life-Saving Therapy." Hosted by Rohit Kohli, MBBS, MS, Division Chief, Gastroenterology, Hepatology, and Nutrition, Children's Hospital Los Angeles, Associate Professor of Pediatrics, University of Southern California

May 3, 2017
Todd Evans, PhD, Peter I. Pressman MD Professor of Surgery, Vice Chair for Research, Chief Division of Research, Department of Surgery, Weill Cornell Medical College. Topic: "Beyond Transcription Factors: Discovering Novel Regulators of Cardiogenesis." Hosted by Ching-Ling (Ellen) Lien, PhD, Assistant Professor, Department of Surgery, Biochemistry and Molecular Medicine, University of Southern California, Children's Hospital Los Angeles

Mary 17, 2017
Wayne G. Shreffler, MD, PhD, Director, Food Allergy Center, Massachusetts General Hospital, Division Chief, Pediatric Allergy and Immunology, MassGeneral Hospital of Children
Principal Investigator, Center for Immunology and Inflammatory Diseases, Associate Professor of Pediatrics, Harvard Medical School. Topic: “Suppression of IgE-mediated Allergy by Oral Immunotherapy.”  Hosted by Jonathan Tam, MD, FAAAAI FACAAI, Assistant Professor of Pediatrics, Medical Director Gores Family Allergy Center, Division of Clinical Immunology & Allergy, Children’s Hospital Los Angeles

May 24, 2017
Leonardo Morsut, PhD, Assistant Professor, Broad CIRM Center and Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Keck School of Medicine. Topic: “Engineering Cells with Synthetic Biology Molecular Tools to Control Their Behavior for Basic Research and Regenerative Medicine Applications.” Hosted by D. Brent Polk, MD, Professor of Pediatrics, Pediatric Gastroenterology, Hepatology & Nutrition, Professor of Biochemistry & Molecular Medicine, Vice Dean for Child Health – USC, University of Southern California and Children’s Hospital Los Angeles

June 14, 2017
Lina Chalak, MD, MSCS, Associate Professor in Pediatrics, Clinical Neonatologist, University of Texas Southwestern Medical Center. Topic: “Advanced Applications of NIRS in Neonatal Asphyxia.” Hosted by Tai-Wei Wu, MD, Assistant Professor of Clinical Pediatrics, USC Keck School of Medicine, Attending Neonatologist, Center for Fetal and Neonatal Medicine Newborn & Infant Critical Care Unit, Children’s Hospital Los Angeles 

June 28, 2017
Anat Erdreich-Epstein, MD, PhD Associate Professor of Pediatrics and Pathology, Pediatric Brain Tumors Program, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles. Topic: “PID1: A Novel Tumor-Suppressor in Brain Cancers.” Hosted by Muller Fabbri, MD, PhD, St. Baldrick's Foundation Scholar, Assistant Professor of Pediatrics and Microbiology & Molecular Immunology, University of Southern California- Keck School of Medicine Norris Comprehensive Cancer Center, Children's Center for Cancer and Blood Diseases Children's Hospital Los Angeles