CHLA Clinical Research Studies

Having volunteers participate in research studies and clinical trials is critical to our research efforts. Thousands of children and families are involved in our patient-centered studies every year. Many of the treatments used today are based on the results of past research studies and clinical trials conducted with our patients. Our scientific and clinical experts take the best ideas from the laboratory -- to the patient -- in the form of promising new treatments.

By searching our study directory, you may identify research that could impact the life of your child or of another child you know. Because the number of available research studies and clinical trials for children nationwide is small, every participant makes a significant contribution.

In addition to enrolling children with certain diseases in order to study treatments and prevention of those diseases, we also need to study healthy children. Ask your child’s doctor about volunteer study options that may be suitable for your child.

Please contact the study staff listed in your search results for more information.

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Study Details - ID: CHLA-21-00026
Health/Science/Disease Category:
Down Syndrome
Purpose of Research:
To investigate if non-invasive screening for cerebrovascular diseases in persons with Down syndrome is feasible with the goal of preventing stroke.
Short Name:
Non-Invasive Screening for Cerebrovascular Disease in Down Syndrome
Full Title of Study:
Non-Invasive Screening for Cerebrovascular Disease in Down Syndrome
Phase/Type of Study:
Children 8-26 years of age with Down syndrome (trisomy 21)
Time Commitment/Requirements:
Three visits, each lasting about 2 hours. Total six hours. Includes a non-sedated MRI (no anesthesia)
Primary Investigator:
Jonathan D. Santoro, MD
Coordinator Contact Name:
Martha Arellano-Garcia
Phone Number:
Email: or
Clinical Trials .Gov Identifier: