CHLA Clinical Research Studies

Having volunteers participate in research studies and clinical trials is critical to our research efforts. Thousands of children and families are involved in our patient-centered studies every year. Many of the treatments used today are based on the results of past research studies and clinical trials conducted with our patients. Our scientific and clinical experts take the best ideas from the laboratory -- to the patient -- in the form of promising new treatments.

By searching our study directory, you may identify research that could impact the life of your child or of another child you know. Because the number of available research studies and clinical trials for children nationwide is small, every participant makes a significant contribution.

In addition to enrolling children with certain diseases in order to study treatments and prevention of those diseases, we also need to study healthy children. Ask your child’s doctor about volunteer study options that may be suitable for your child.

Please contact the study staff listed in your search results for more information.

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Study Details - ID: CCI-11-00083
Health/Science/Disease Category:
Sickle Cell Anemia
Purpose of Research:
This study uses sensitive measures of brain blood flow an its response to change to inhaled oxygen levels to determine how the brain protects its oxygen supply.
Short Name:
Brain Blood Flow
Full Title of Study:
Brain blood flow and its response to changes to inhaled oxygen levels in subjects with and without sickle cell disease
Phase/Type of Study:
Observational & Testing
1. known diagnosis of sickle cell disease or chronic anemia. 2. Also accepting healthy control volunteers. 3. Must be 7 years or older. 4. Must be able to tolerate the MRI procedure.
Time Commitment/Requirements:
2 day visit within 30 days. Each visit will take roughly about 3-4hrs. Compensation provided.
Primary Investigator:
Dr. John C. Wood
Coordinator Contact Name:
Mike K. Gawad, BSc, CCRP or Obdulio Carreras
Phone Number:
(323) 361-3313 or 323-361-4100
Email: or
Clinical Trials .Gov Identifier: