CHLA Clinical Research Studies

Having volunteers participate in research studies and clinical trials is critical to our research efforts. Thousands of children and families are involved in our patient-centered studies every year. Many of the treatments used today are based on the results of past research studies and clinical trials conducted with our patients. Our scientific and clinical experts take the best ideas from the laboratory -- to the patient -- in the form of promising new treatments.

By searching our study directory, you may identify research that could impact the life of your child or of another child you know. Because the number of available research studies and clinical trials for children nationwide is small, every participant makes a significant contribution.

In addition to enrolling children with certain diseases in order to study treatments and prevention of those diseases, we also need to study healthy children. Ask your child’s doctor about volunteer study options that may be suitable for your child.

Please contact the study staff listed in your search results for more information.

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Study Details - ID: CCI-10-00235
Health/Science/Disease Category:
Purpose of Research:
Develop better ways of screening and diagnosing certain types of brain injuries in infants and children who are born with and without congenital heart disease.
Short Name:
Fetal Substudy (CHD & Dev)
Full Title of Study:
Correlation of Neonatal Brain Imaging and Neurocognitive Assessment (Fetal Sub-study: Congenital Heart Disease patients and Control patients)
Phase/Type of Study:
Phase 2/Observational
Pregnant women carrying a child diagnosed with CHD.
Time Commitment/Requirements:
Six years from birth to complete neurodevelopmental testing and 6 year post operation MRI. The parents also have the option to only provide the fetal and newborn post operative MRI imaging and/or the 6 year post op MR imaging and not participate in the neurodevelopmental testing.
Primary Investigator:
Dr. Jodie Votava-Smith
Coordinator Contact Name:
Nhu Tran
Phone Number:
Clinical Trials .Gov Identifier: