Research News Listing

Published on May 26, 2015
21386-chla-placeholders_320x165_v2_0.jpg Understanding how cells become coronary vessels may lead to advances in repairing heart damage LOS ANGELES (May 26, 2015)-The heart has its own dedicated blood supply, with coronary arteries that supply oxygen-rich blood to the heart and cardiac veins that remove deoxygenated... Read More
Published on May 18, 2015
21386-chla-placeholders_320x165_v2_0.jpg Free, portable and privacy-protected technology gives patient families full access to imaging data and diagnostic reports Physicians use a growing array of diagnostic imaging equipment, such MR, CT, ultrasound and X-rays.  Due to the massive size of the digital files... Read More
Published on May 14, 2015
21386-chla-placeholders_320x165_v2_0.jpg Children achieve complete remission despite few remaining leukemia cells following chemotherapy Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. This disease includes two subtypes, B-cell and T-cell leukemia, depending upon the type of white blood cell... Read More
Published on May 13, 2015
21386-chla-placeholders_320x165_v2_0.jpg Researchers at Children’s Hospital Los Angeles have made an important step toward finding a target in the fight against drug-resistant neuroblastoma (NBL), the most common solid malignancy found, outside of the skull, in children. Led by Muller Fabbri, MD, PhD, of the... Read More
Published on April 24, 2015
21386-chla-placeholders_320x165_v2_0.jpg Recombinant factor VIII fusion protein safely extends time between infusions Children with hemophilia A require three to four infusions each week to prevent bleeding episodes, chronic pain and joint damage. The effect on quality of life can be significant, due to time and... Read More
Published on March 30, 2015
21386-chla-placeholders_320x165_v2_0.jpg Characterizing associations between socioeconomic factors and children’s brain development, a team including investigators from nine universities across the country reports correlative links between family income and brain structure. Relationships between the brain and family... Read More
Published on March 26, 2015
21386-chla-placeholders_320x165_v2_0.jpg Novel device has received Humanitarian Use Device designation from FDA A team of investigators at Children’s Hospital Los Angeles and the University of Southern California have developed the first fully implantable micropacemaker designed for use in a fetus with complete... Read More
Published on March 25, 2015
21386-chla-placeholders_320x165_v2_0.jpg Everyday pollutants in and outside the home can be bad for the environment…and bad for your baby’s brain Researchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles (CHLA) and colleagues at Columbia University’s Center for Children’s... Read More
Published on March 18, 2015
21386-chla-placeholders_320x165_v2_0.jpg Investigators identify new role for cytokine VEGFA in the metastasis of neuroblastoma Healthy bone is continuously involved in a dynamic process that includes bone deposition and bone resorption. However, when a person has cancer that spreads to the bone and bone marrow,... Read More
Published on March 18, 2015
21386-chla-placeholders_320x165_v2_0.jpg By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA), along with colleagues in Mexico and Canada, have identified a promising new approach for the treatment of... Read More
Published on January 26, 2015
21386-chla-placeholders_320x165_v2_0.jpg Protein found capable of selectively binding and delivering a ‘death signal’ to leukemia cells Resistance of leukemia cells to contemporary chemotherapy is one of the most formidable obstacles to treating acute lymphoblastic leukemia (ALL), the most common form of... Read More
Published on January 26, 2015
21386-chla-placeholders_320x165_v2_0.jpg Deepa Bhojwani, MD, joins Children’s Hospital Los Angeles (CHLA) as director of the Leukemia/Lymphoma program within the Children’s Center for Cancer and Blood Diseases on February 15, 2015. She will also serve as an associate professor in the Division of Hematology, Oncology... Read More
Published on January 22, 2015
21386-chla-placeholders_320x165_v2_0.jpg  Full recovery and normal function restored in mouse models following mild injury A new study by researchers at Children’s Hospital Los Angeles has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Using... Read More
Published on January 20, 2015
21386-chla-placeholders_320x165_v2_0.jpg  New study offers hope of future treatments to help prevent weight problems Our subconscious motivation to eat is powerfully and dynamically regulated by hormone signals.  The gut-derived hormone ghrelin is one such key regulator, promoting appetite through its... Read More
Published on January 8, 2015
21386-chla-placeholders_320x165_v2_0.jpg Regenerative medicine technique brings surgeons one step closer to helping patients   LOS ANGELES (January 8, 2015)-A new study by researchers at Children’s Hospital Los Angeles has shown that tissue-engineered small intestine grown from human cells replicates... Read More
Published on November 4, 2014
21386-chla-placeholders_320x165_v2_0.jpg Disturbances in the early stages of brain growth, such as preterm birth – when many of the brain’s structures have not yet fully developed – appears to affect the brain’s neuro-circuitry, which may explain premature babies’ higher risk of neurodevelopmental disorders including... Read More
Published on October 30, 2014
21386-chla-placeholders_320x165_v2_0.jpg Evaluation of pediatric patients before and after surgery suggests optimal duration of chemotherapy treatment may vary from current standard of care A study of pediatric patients with hepatoblastoma led by researchers at Children’s Hospital Los Angeles (CHLA) suggests an... Read More
Published on October 27, 2014
21386-chla-placeholders_320x165_v2_0.jpg Obese youths with acute lymphoblastic leukemia (ALL) are known to have worse outcomes than their lean counterparts. To find out why, investigators at Children’s Hospital Los Angeles studied patients who were obese at the time of their diagnosis with ALL to determine if body mass... Read More
Published on October 24, 2014
21386-chla-placeholders_320x165_v2_0.jpg Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics at Children's Hospital Los Angeles, has received a grant of nearly $1 million from Autism Speaks, the world’s leading autism science and advocacy organization.  Funding will support research into the treatment... Read More
Published on October 16, 2014
21386-chla-placeholders_320x165_v2_0.jpg In a first step toward future human therapies, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have shown that esophageal tissue can be grown in vivo from both human and mouse cells. The study has been published online in the journal Tissue... Read More

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