Research News Listing

Published on June 20, 2017
21386-chla-placeholders_320x165_v2_0.jpg Next-generation sequencing panel tests for full spectrum of childhood cancers Today, a team of investigators at Children’s Hospital Los Angeles launched OncoKids®, a next-generation sequencing-based panel specifically designed for pediatric cancers. OncoKids® is intended to... Read More
Published on May 16, 2017
160738878317_0.jpg Signal processing technique improves analysis of ultrasonic vocalizationsVocalization plays a significant role in social communication across species such as speech by humans and song by birds. Male mice produce ultrasonic vocalizations in the presence of females and both sexes... Read More
Published on May 16, 2017
CHLA-HealthyLeft DiseasedRight.jpgWEB.jpg Role of NKT and CD8 T-cells demonstrated in mice and humans A team of investigators led by Rohit Kohli, MBBS, MS, of Children’s Hospital Los Angeles, has identified key inflammatory cells involved in nonalcoholic fatty liver disease.  Current treatment for the disorder... Read More
Published on May 15, 2017
Abdel_Azim_Hisham_03_2015_003_4x6_0.jpg Prevents production of antibodies that fight infection in children after bone marrow transplantation Researchers from the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles examined the mechanisms of B cell immune reconstitution in pediatric... Read More
Published on May 5, 2017
CHLA-Pat Levitt.jpg Signal processing technique improves analysis of ultrasonic vocalizations Vocalization plays a significant role in social communication across species such as speech by humans and song by birds. Male mice produce ultrasonic vocalizations in the presence of females and both... Read More
Published on April 27, 2017
160065422882_0.jpg Christopher Russell, MD, a hospitalist at Children’s Hospital Los Angeles specializing in pediatric patients with tracheostomies, noticed that many of these children have a high percentage of being re-admitted to the hospital for respiratory conditions.  A tracheostomy is a... Read More
Published on April 21, 2017
159840235687_0.jpg Willowbrook State School, Staten Island, NY   50 years ago, children with developmental disabilities such as autism spectrum disorder (ASD) were routinely institutionalized because families were ill-equipped to care for them.Today, thanks to research funded in part by the... Read More
Published on April 21, 2017
159833020117_0.jpg Join Children’s Hospital Los Angeles in the March For Science on Saturday, April 22, 2017March For Science Los Angeles http://marchforsciencela.com/ Register to attend your local march https://www.marchforscience.com/ Read More
Published on April 20, 2017
In 1963, the death of baby Patrick Bouvier Kennedy, who was born 5 ½ weeks premature and died from respiratory distress syndrome, gripped the nation.  At that time, medicine had very little to offer premature babies with respiratory distress, but baby Patrick’s death put a... Read More
Published on April 20, 2017
Twenty years ago, a child with inflammatory arthritis had a very different life than a child with that same disease has today. In 1997, that child suffered from chronic pain and lack of mobility that kept them homebound – unable to go to school, have the opportunity to make... Read More
Published on April 18, 2017
“My goal is to decrease childhood blindness by treating pediatric eye disease in an innovative way,” says Bibiana Jin Reiser, MD, MS, director of the Cornea and Glaucoma Institute at CHLA. Using technology developed for adults, she is optimizing it to treat children.“The disease... Read More
Published on April 17, 2017
Research is a team sport. Each advance is incremental – small but crucial in reaching the next, significant step toward finding a solution. Science is currently under a great deal of scrutiny because of how it is conducted and how it is funded.  At Children’s Hospital Los... Read More
Published on April 11, 2017
Erdreich-Epstein_Anat_11-13-05.jpg Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have found that the gene PID1 enhances killing of medulloblastoma and glioblastoma cells. Medulloblastoma is the most commonly occurring malignant primary brain tumor in children; glioblastoma is... Read More
Published on April 6, 2017
child_rad_onc resized.jpg A team of investigators has determined that young children participating in a clinical trial to assess the effectiveness of reduced radiotherapy did worse when there were deviations from the treatment protocol. Results of the study will be available online in advance of... Read More
Published on April 5, 2017
159238688162_0.jpg Zebrafish heart with prominent coronary vessels (marked by transgenic fluorescent reporters)Heart disease is among the leading causes of death for both adults and children. A heart attack (or myocardial infarction) occurs when the heart is deprived of oxygen due to blockage of a... Read More
Published on March 20, 2017
158631813237_0.jpg Brain scans of chronically depressed patients before and during treatment. Left: Before treatment, depressed patients had a thicker cortex in the frontal, temporal and parietal lobes of the brain (shown in red). Right: Over 10 weeks of medication, these regions (shown in blue)... Read More
Published on March 7, 2017
CHLA-Bansal-Peterson.jpg A study led by Ravi Bansal, PhD, and Bradley S. Peterson, MD, of The Saban Research Institute of Children’s Hospital Los Angeles, has found structural differences in the cerebral cortex of patients with depression and that these differences normalize with appropriate medication... Read More
Published on March 3, 2017
157962641817_0.jpg In a study led by Barbara Driscoll, PhD, of The Saban Research Institute of Children’s Hospital Los Angeles, researchers demonstrate, for the first time that inhaled resveratrol treatments slow aging-related degenerative changes in mouse lung.  Lung aging, characterized by... Read More
Published on February 28, 2017
CHLA-Zebrafish-heart.jpg Research will lead to a better understanding of coronary vessel development and revascularization Ching-Ling (Ellen) Lien, PhD, an investigator at The Saban Research Institute of Children’s Hospital Los Angeles, has been awarded nearly $1.7 million, over a four year period,... Read More
Published on February 22, 2017
CHLA-Lung-tissue.jpg In a study led by Barbara Driscoll, PhD, of The Saban Research Institute of Children’s Hospital Los Angeles, researchers demonstrate, for the first time that inhaled resveratrol treatments slow aging-related degenerative changes in mouse lung.  Lung aging, characterized by... Read More

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