Research News Listing

Published on March 14, 2016
CT images 2 - nc, web.jpg Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities.  In a study designed to assess bone, muscle and fat tissue distribution in the lower legs of children with this... Read More
Published on March 10, 2016
cropped, web.jpg Study suggests macrophage activation as possible reason for differential bone loss in adolescent males Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division... Read More
Published on February 23, 2016
Robert Seeger, MD, sized.jpg Robert Seeger, MD, division head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) has been selected for the 2016 Lifetime Achievement Award from the Pediatric Blood and Marrow Transplant Consortium (PBMC... Read More
Published on February 18, 2016
shutterstock_232207735 (1).jpg Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research.  The assay would be CHLA’s first NGS panel designed to target biomarkers associated... Read More
Published on February 10, 2016
GrikWieck PLOS web.jpg Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have created a novel model for studying a lung disorder of newborn babies. Their study, published in PLOS ONE on February 10, describes the first model that allows investigators to consider the... Read More
Published on February 4, 2016
Etan Orgel, MD, MS.jpg Investigators at Children’s Hospital Los Angeles have found that significant bone loss – a side effect of chemotherapy for acute lymphoblastic leukemia (ALL) – occurs during the first month of treatment, far earlier than previously assumed. Results of the study will be available... Read More
Published on January 28, 2016
resize.jpg An interdisciplinary research team at The Saban Research Institute of Children’s Hospital Los Angeles has found that body mass index (BMI) is an inadequate method for estimating changes in body fat and obesity in children with leukemia. Investigators determined that the... Read More
Published on January 27, 2016
MarachellianNewsroom.png Building upon more than two decades of basic research conducted at Children’s Hospital Los Angeles, Araz Marachelian, MD, of CHLA, and her colleagues at pediatric academic centers across the U. S., have shown that an immunotherapy that until now has only been available to... Read More
Published on January 20, 2016
Depression cover image.jpg Building on a 30-year, three-generation study of depressed individuals, their children and offspring, a study published in the journal Psychiatry Research: Neuroimaging provides a better understanding of the familial risk for depression and the role neuroplasticity might have in... Read More
Published on December 16, 2015
21386-chla-placeholders_320x165_v2_0.jpg Two philanthropic gifts, totaling $4 million, have been pledged in support of The Vision Center at Children’s Hospital Los Angeles, an international referral center for children with complex eye diseases. A $2 million gift from the Larry & Celia Moh Foundation to The... Read More
Published on December 3, 2015
Newborn brain images V2.jpg In the first study of its kind, researchers have shown that inadequate maternal iron intake during pregnancy exerts subtle effects on infant brain development.  Their findings have been published online by the journal Pediatric Research. The research—led by principal... Read More
Published on November 30, 2015
facial expressions.jpg Individuals with autism spectrum disorder (ASD) often have difficulty recognizing and interpreting how facial expressions convey various emotions – from joy to puzzlement, sadness to anger.  This can make it difficult for an individual with ASD to successfully navigate... Read More
Published on November 3, 2015
ORGEL, ETAN 2.jpg More children are surviving malignant brain tumors than in the past, thanks to the use of intense treatments using platinum-based chemotherapy (cisplatin and high-dose carboplatin).  Unfortunately, the therapy has a known side effect of permanent hearing loss,... Read More
Published on October 8, 2015
hypothermia team.jpg Latest study shows effects of hypothermia on infant brain metabolism using MRS imaging A unique study at Children’s Hospital Los Angeles of newborns treated with hypothermia for hypoxic-ischemic encephalopathy (HIE) – a condition that occurs when the brain is deprived of an... Read More
Published on October 1, 2015
TE Colon_Grik 50%.jpg A study by scientists at Children’s Hospital Los Angeles has shown that tissue-engineered colon derived from human cells is able to develop the many specialized nerves required for function, mimicking the neuronal population found in native colon. These specialized neurons,... Read More
Published on October 1, 2015
11_17_14 ED photo 10%.jpg In a study to be published on Oct.1 by the journal Pediatric Emergency Care, investigators at Children’s Hospital Los Angeles piloted a brief mental health screening tool to be used with patients accessing the emergency department for medical complaints who might be at risk... Read More
Published on September 30, 2015
Newsroom.jpg Study on substance use and adolescent brain development to look at 10,000 children at research institutions throughout the U.S. As part of a landmark study about the effects of adolescent substance use on the developing brain called the Adolescent Brain Cognitive Development... Read More
Published on September 28, 2015
21386-chla-placeholders_320x165_v2_0.jpg A team of researchers from the Trauma Program at Children’s Hospital Los Angeles conclude that an admission hematocrit provides a reliable screening test for identifying pediatric patients who are at an increased risk of bleeding after injury.  Their retrospective review of... Read More
Published on September 25, 2015
Polk 20%.jpg Investigators at Children’s Hospital Los Angeles have found that a common therapeutic target for the treatment of inflammatory bowel disease (IBD) may actually protect against intestinal inflammation or colitis by inhibiting pathogenic T-cells. This discovery, reported in the... Read More
Published on September 21, 2015
Peterson.jpg Neural dysfunction in cognitive control circuits during adolescence could be predictor of psychotic disorders Researchers led by Bradley S. Peterson, MD, director of the Institute for the Developing Mind at Children’s Hospital Los Angeles, have shown that lower levels of... Read More

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