Research News Listing

Published on November 23, 2016
Alex Judkins 2014 cropped.jpg May create opportunities for new, less aggressive, therapies for children with subset of brain tumors A multi-institutional group of researchers, led by investigators at Children’s Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive... Read More
Published on November 23, 2016
Peterson.jpg Researchers at Children’s Hospital Los Angeles (CHLA) have conducted the first study of its kind, using proton magnetic resonance spectroscopy (MRS) to look at brain regions in both adults and children who stutter. Consistent with past functional MRI studies, their findings... Read More
Published on November 11, 2016
Untitled.jpg Scientists at Children’s Hospital Los Angeles have developed a tissue-engineered model of lung and trachea which contains the diverse cell types present in the human respiratory tract.  The study, led by principal investigator Tracy Grikscheit, MD, a pediatric surgeon and... Read More
Published on November 10, 2016
Yong-Mi Kim, MD, PhD.jpg Yong-Mi Kim, MD, PhD, of The Saban Research Institute of Children’s Hospital Los Angeles, has been awarded a 3 year translational research program (TRP) grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients... Read More
Published on October 20, 2016
Breath In, Branch Out.gif A study by researchers from The Saban Research Institute of Children’s Hospital Los Angeles reveals a promising therapeutic target for improving lung function in infants.  Their study, now published online by the American Journal of Physiology-Lung Cellular and Molecular... Read More
Published on October 18, 2016
Shahab new cropped B.jpg A team of investigators at Children’s Hospital Los Angeles has received a major, three-year grant from the V Foundation for Cancer Research to study the effects of chemoimmunotherapy in children with neuroblastoma. Neuroblastoma is the most common solid tumor occurring... Read More
Published on October 17, 2016
cropped.jpg Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified an unsuspected and critical role of the MDM2 oncogene in promoting expression of the MYCN oncogene that is required for growth and survival of retinoblastoma cells.  Their results... Read More
Published on October 11, 2016
Robert Seeger, MD, sized.jpg A study by a multidisciplinary team of researchers from The Saban Research Institute of Children’s Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody... Read More
Published on September 14, 2016
David Warburton resized.jpg Real-time endoscopic monitoring technology expected to improve respiratory health of military personnel in the field David Warburton, MD, of The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) has been awarded more than $2.3 million from the Department of... Read More
Published on September 12, 2016
Perrin resized.jpg In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have isolated human nephron progenitor (NP) cells.  Their results, published online in the journal Stem Cell Translational Medicine, will... Read More
Published on September 1, 2016
21386-chla-placeholders_320x165_v2_0.jpg Co-occurrences could have broad clinical implications for patient care over a lifetime Researchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles have analyzed current gene-disease findings to understand why people with neurodevelopmental and... Read More
Published on August 30, 2016
human Teli-1  web.jpg A research team led by investigators at The Saban Research Institute of Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver (TELi) was found to contain normal structural... Read More
Published on August 17, 2016
Leo Mascarenhas, MD.jpg In an innovative, first-in-pediatrics study, available only at Children’s Hospital Los Angeles (CHLA), researchers will be enrolling children between 1 and 18 years of age who have certain types of relapsed or treatment-resistant cancer. The aim of this investigator-initiated... Read More
Published on August 15, 2016
21386-chla-placeholders_320x165_v2_0.jpg Study suggests substantial complications may impact daily activities, long after initial cancer diagnosis A team of researchers from nine leading academic hospitals and research centers have published a paper in the early online edition of the journal Cancer that describes... Read More
Published on August 2, 2016
E44 PPARgamma meninges 63x zoom2.jpg Study shows why glucose levels are reduced in the brains of children with E. coli K1 meningitis Escherichia coli K1 (E. coli K1) continues to be a major threat to the health of young infants.  Affecting the central nervous system, it causes neonatal meningitis by... Read More
Published on July 27, 2016
St Baldrick's Foundation.jpg Five physician-researchers with the Center for Childhood Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) have been awarded more than $800,000 in grants from the St. Baldrick’s Foundation, the largest private funder of childhood cancer research. ... Read More
Published on July 27, 2016
J%20Bender%20Headshot2.jpg A study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) suggests that maternal HIV infection influences the microbiome of their HIV-uninfected infants.  Their findings, reported online in the journal Science Translational... Read More
Published on July 25, 2016
SALINAS,%20DANIELI.jpg A study by researchers at Children’s Hospital Los Angeles (CHLA), Brigham and Women’s Hospital and the California Department of Public Health suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive... Read More
Published on July 8, 2016
Michele Kipke PhD, and Thomas Buchanan, MD web.jpg Clinical and Translational Science Award will be Catalyst for Clinical and Community Research On June 30, 2016, a team of researchers led by Thomas Buchanan, MD, Michele Kipke PhD and Jonathan Samet, MD, of the Keck School of Medicine of the University of Southern California... Read More
Published on June 20, 2016
Pat Levitt, PhD.jpg Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Results of the study have been published in the Journal of... Read More

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