Research News Listing

Published on June 27, 2018
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CHLA and USC researchers team up to design and implant a minimally-invasive device in area around the heart.   Investigators at Children's Hospital Los Angeles and the University of Southern California have demonstrated the feasibility of implanting a... Read More
Published on June 22, 2018
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Children's Hospital Los Angeles contributes to large, multisite international ‘Brainstorm’ Project   Investigators found that many common psychiatric disorders are deeply connected on a genetic level, sharing specific genetic risk factors, underscoring the need to... Read More
Published on June 20, 2018
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“We thought she had a bug bite,” says Michelle’s mom, “but it turned out to be cancer.” After seeing several doctors, the family was referred to Children’s Hospital Los Angeles. Because the team of specialists at CHLA had access to a specialized genetic test that they helped... Read More
Published on June 18, 2018
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Seattle Children’s, with participating members Children’s Hospital Los Angeles, Children’s National Health System and BC Children’s Hospital, has launched CureWorks, an international collaborative of leading academic children’s hospitals determined to accelerate the development... Read More
Published on May 24, 2018
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Pat Levitt, PhD, has been named Vice President, Chief Scientific Officer and Director of The Saban Research Institute of Children’s Hospital Los Angeles. Read More
Published on May 16, 2018
10E4_CHLA90_2[2] (tumor-associated macrophages)
Findings suggest new therapeutic approach for children with high-risk disease Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages—a type of... Read More
Published on May 16, 2018
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Investigators at Children’s Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium... Read More
Published on February 28, 2018
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Less-toxic lymphoid regimens are more likely to obtain remission in mixed phenotype acute leukemia (MPAL) A study at Children’s Hospital Los Angeles is shedding new light on the best therapeutic approach for a rare and aggressive leukemia called mixed phenotype acute... Read More
Published on February 27, 2018
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A landmark study published in the Journal of Neuroscience on February 26 reveals that activation of a pregnant mother’s immune system can affect her baby’s brain development. A team of researchers led by Bradley Peterson, MD, director of the Institute for the Developing Mind in... Read More
Published on February 21, 2018
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Three quarters of patients, both adults and children, with a variety of advanced cancers occurring in different sites of the body responded to larotrectinib, a novel therapy that targets a specific genetic mutation. Results of this multisite phase 1/2 trial have been published... Read More
Published on February 5, 2018
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Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I... Read More
Published on December 14, 2017
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Researchers have demonstrated for the first time that extracellular vesicles – tiny protein-filled structures – isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with a type of chronic kidney disease. The... Read More

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