Research News Listing

Published on June 22, 2017
CHLA-Needle-in-a-Haystack.jpg Improved disease assessment aids in prediction of relapse in children Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when... Read More
Published on June 21, 2017
CHLA-Alternative-Disposable-Diapers.jpg Two physicians examine the challenges and benefits of using an age-old practice to toilet train their infant daughter You know that disposable diapers are ecologically questionable, but cloth diapers seem too messy for you and your child -- is there an alternative? The... Read More
Published on June 20, 2017
21386-chla-placeholders_320x165_v2_0.jpg Next-generation sequencing panel tests for full spectrum of childhood cancers Today, a team of investigators at Children’s Hospital Los Angeles launched OncoKids®, a next-generation sequencing-based panel specifically designed for pediatric cancers. OncoKids® is intended to... Read More
Published on May 16, 2017
CHLA-HealthyLeft DiseasedRight.jpgWEB.jpg Role of NKT and CD8 T-cells demonstrated in mice and humans A team of investigators led by Rohit Kohli, MBBS, MS, of Children’s Hospital Los Angeles, has identified key inflammatory cells involved in nonalcoholic fatty liver disease.  Current treatment for the disorder... Read More
Published on May 15, 2017
Abdel_Azim_Hisham_03_2015_003_4x6_0.jpg Prevents production of antibodies that fight infection in children after bone marrow transplantation Researchers from the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles examined the mechanisms of B cell immune reconstitution in pediatric... Read More
Published on May 5, 2017
CHLA-Pat Levitt.jpg Signal processing technique improves analysis of ultrasonic vocalizations Vocalization plays a significant role in social communication across species such as speech by humans and song by birds. Male mice produce ultrasonic vocalizations in the presence of females and both... Read More
Published on April 11, 2017
Erdreich-Epstein_Anat_11-13-05.jpg Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have found that the gene PID1 enhances killing of medulloblastoma and glioblastoma cells. Medulloblastoma is the most commonly occurring malignant primary brain tumor in children; glioblastoma is... Read More
Published on April 6, 2017
child_rad_onc resized.jpg A team of investigators has determined that young children participating in a clinical trial to assess the effectiveness of reduced radiotherapy did worse when there were deviations from the treatment protocol. Results of the study will be available online in advance of... Read More
Published on March 7, 2017
CHLA-Bansal-Peterson.jpg A study led by Ravi Bansal, PhD, and Bradley S. Peterson, MD, of The Saban Research Institute of Children’s Hospital Los Angeles, has found structural differences in the cerebral cortex of patients with depression and that these differences normalize with appropriate medication... Read More
Published on February 28, 2017
CHLA-Zebrafish-heart.jpg Research will lead to a better understanding of coronary vessel development and revascularization Ching-Ling (Ellen) Lien, PhD, an investigator at The Saban Research Institute of Children’s Hospital Los Angeles, has been awarded nearly $1.7 million, over a four year period,... Read More
Published on February 22, 2017
CHLA-Lung-tissue.jpg In a study led by Barbara Driscoll, PhD, of The Saban Research Institute of Children’s Hospital Los Angeles, researchers demonstrate, for the first time that inhaled resveratrol treatments slow aging-related degenerative changes in mouse lung.  Lung aging, characterized by... Read More
Published on February 6, 2017
CHLA-Tarantula-web.jpg A team of investigators, led by Bradley S. Peterson, MD, director of the Institute for the Developing Mind at Children’s Hospital Los Angeles, and Paul Siegel, PhD, associate professor of psychology at Purchase College of the State University of New York, have found that... Read More
Published on January 25, 2017
CHLA-3D-rendering-of-DNA.jpg Investigators at Children’s Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome (SBS) using a novel zebrafish model and by performing intensive gene sequencing. This approach to determining which genes are... Read More
Published on January 10, 2017
CHLA-Larry-Yin -2.jpg Funding supports initiatives to battle high obesity rates in West Los Angeles The USC University Center of Excellence on Developmental Disabilities (UCEDD) at Children’s Hospital Los Angeles was awarded $880,000 from the Los Angeles County Department of Public Health with... Read More
Published on January 3, 2017
CHLA-Peterson.jpg A study led by researchers at Children’s Hospital Los Angeles demonstrates what lead investigator Bradley Peterson, MD, calls “a critical mass of evidence” of a common underlying lifelong vulnerability in both children and adults who stutter. They discovered that regional... Read More
Published on December 2, 2016
Freyer.jpg Investigators from Children’s Hospital Los Angeles and 37 other Children’s Oncology Group hospitals in the U.S. and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer. Results of this randomized,... Read More
Published on November 23, 2016
Alex Judkins 2014 cropped.jpg May create opportunities for new, less aggressive, therapies for children with subset of brain tumors A multi-institutional group of researchers, led by investigators at Children’s Hospital Los Angeles and the University of Michigan, have identified a simple and inexpensive... Read More
Published on November 23, 2016
Peterson.jpg Researchers at Children’s Hospital Los Angeles (CHLA) have conducted the first study of its kind, using proton magnetic resonance spectroscopy (MRS) to look at brain regions in both adults and children who stutter. Consistent with past functional MRI studies, their findings... Read More
Published on November 11, 2016
Untitled.jpg Scientists at Children’s Hospital Los Angeles have developed a tissue-engineered model of lung and trachea which contains the diverse cell types present in the human respiratory tract.  The study, led by principal investigator Tracy Grikscheit, MD, a pediatric surgeon and... Read More
Published on November 10, 2016
Yong-Mi Kim, MD, PhD.jpg Yong-Mi Kim, MD, PhD, of The Saban Research Institute of Children’s Hospital Los Angeles, has been awarded a 3 year translational research program (TRP) grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients... Read More

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