Research News Listing
Published on July 22, 2019
Chemotherapy and radiation target cancer cells but these treatments produce unwanted side effects on healthy tissue. The intestines are particularly sensitive to this toxicity. A better understanding of how intestinal tissue repairs itself in response to injury could help... Read More
Published on July 1, 2019
Pediatricians have observed that a baby’s early infection with flu impacts their later response to the virus as well as how protected they are by vaccination. To better understand how this “immunological imprinting” occurs, the National Institute of Allergy and Infectious... Read More
Published on June 13, 2019
For the future of medicine, clinicians and scientists at Children’s Hospital Los Angeles look to our genes.
The age of one-size-fits-all medicine is fading. Taking its place is an era of personalized medicine – the practice of tailoring disease prevention, diagnosis, and... Read More
Published on June 7, 2019
Pediatric surgeon Tracy Grikscheit of Children’s Hospital Los Angeles and colleagues describe the progress and challenges of building new intestinal tissue for babies in need.
Babies born prematurely often face intense medical challenges, including intestines that are... Read More
Published on May 16, 2019
Children’s Hospital Los Angeles researcher awarded $3.7M to study neural circuits associated with developmental disorders.
Pat Levitt, PhD, Chief Scientific Officer at Children’s Hospital Los Angeles and Simms/Mann Chair in Developmental Neurogenetics, received a $3.7M grant... Read More
Published on April 26, 2019
Doctors at Children’s Hospital Los Angeles use novel software to improve accuracy of cancer treatment
Doctors at Children’s Hospital Los Angeles continue to lead the field of radiation oncology by pushing the leading edge of technological advances. A new report by Arthur Olch... Read More
Published on April 8, 2019
Stress creates risk, maternal education provides resilience
A study of 70 mothers and their infants suggests that the impact of maternal stress on neurodevelopment is detectable by electroencephalography (EEG) at 2 months of age. The team of investigators, co-led by Pat... Read More
Published on April 5, 2019
Clinical psychologists implement child-parent psychotherapy in The Steven & Alexandra Cohen Foundation Newborn and Infant Critical Care Unit at Children's Hospital Los Angeles
Bringing a baby into the world involves many firsts – mothers and fathers are discovering their... Read More
Published on March 15, 2019
Considering the implications of precision medicine for diagnosis and treatment of pediatric cancers
Research performed over the last several decades has led to an increased understanding of the genetics of cancer. The clinical application of this knowledge for pediatric... Read More
Published on March 14, 2019
CHLA researcher receives $1.6M grant to study cellular and genetic changes that underlie retinoblastoma.
Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age and accounts for approximately 4% of childhood cancers. If not diagnosed... Read More
Published on February 28, 2019
Children’s Hospital Los Angeles has been awarded a $1.36M grant from The Leona M. and Harry B. Helmsley Charitable Trust to adapt a patient-driven model of care that Clinical Diabetes Director, Jennifer Raymond, MD, MCR, developed to increase treatment compliance among difficult... Read More
Published on January 30, 2019
With autism on the rise, science is on the hunt for answers. New research at Children’s Hospital Los Angeles looks at autism in a different way.
One in 59 children are diagnosed with an Autism Spectrum Disorder (ASD), a wide array of conditions affecting a child’s social,... Read More
Published on December 5, 2018
New study reveals how cancer manipulates our immune system to become harder to treat
Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so... Read More
Published on December 5, 2018
Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality. She has been awarded nearly $1.3 million by the... Read More
Published on October 24, 2018
According to a first-of-its-kind international study, a new definition of Pediatric Acute Respiratory Distress Syndrome (PARDS) results in a more accurate diagnosis of many more children with the rapidly progressive disease than the widely used adult definition. Read More
Published on October 2, 2018
Combining a new, targeted drug with chemotherapy shows promise in children with advanced disease
A phase 2 clinical trial has found that combining a novel compound called alisertib with chemotherapy has anti-tumor activity in children with high-risk, relapsed neuroblastoma.... Read More
Published on September 21, 2018
Lee Helman, MD, of Children’s Hospital Los Angeles, is a founding members of a novel cancer consortium announced at the Biden Summit on Sept. 21, 2018
Former Vice President Joe Biden and Dr. Jill Biden hosted the national Biden Cancer Summit, on Sept. 21, to highlight the... Read More
Published on September 19, 2018
Investigator at Children’s Hospital Los Angeles Awarded $2.3 Million to Study Bone Loss Associated with Cerebral Palsy
Cerebral palsy (CP) is the most common physical disability originating in childhood. Approximately 2 of every 1000 babies born acquire this... Read More
Published on September 19, 2018
Finding in retinoblastoma could lead to new interventions
Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the... Read More
Published on August 23, 2018
CHLA investigators spotlight the need to include obese and overweight subjects in metabolic research to prevent potentially misleading outcomes.
Children's Hospital Los Angeles investigators have demonstrated the need to include a growing constituency of obese and... Read More