Research News Listing

Published on February 28, 2019
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Children’s Hospital Los Angeles has been awarded a $1.36M grant from The Leona M. and Harry B. Helmsley Charitable Trust to adapt a patient-driven model of care that Clinical Diabetes Director, Jennifer Raymond, MD, MCR, developed to increase treatment compliance among difficult... Read More
Published on January 30, 2019
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With autism on the rise, science is on the hunt for answers. New research at Children’s Hospital Los Angeles looks at autism in a different way. One in 59 children are diagnosed with an Autism Spectrum Disorder (ASD), a wide array of conditions affecting a child’s social,... Read More
Published on December 5, 2018
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New study reveals how cancer manipulates our immune system to become harder to treat Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so... Read More
Published on December 5, 2018
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Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality. She has been awarded nearly $1.3 million by the... Read More
Published on October 24, 2018
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According to a first-of-its-kind international study, a new definition of Pediatric Acute Respiratory Distress Syndrome (PARDS) results in a more accurate diagnosis of many more children with the rapidly progressive disease than the widely used adult definition. Read More
Published on October 2, 2018
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Combining a new, targeted drug with chemotherapy shows promise in children with advanced disease A phase 2 clinical trial has found that combining a novel compound called alisertib with chemotherapy has anti-tumor activity in children with high-risk, relapsed neuroblastoma.... Read More
Published on September 21, 2018
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Lee Helman, MD, of Children’s Hospital Los Angeles, is a founding members of a novel cancer consortium announced at the Biden Summit on Sept. 21, 2018 Former Vice President Joe Biden and Dr. Jill Biden hosted the national Biden Cancer Summit, on Sept. 21, to highlight the... Read More
Published on September 19, 2018
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Investigator at Children’s Hospital Los Angeles Awarded $2.3 Million to Study Bone Loss Associated with Cerebral Palsy   Cerebral palsy (CP) is the most common physical disability originating in childhood. Approximately 2 of every 1000 babies born acquire this... Read More
Published on September 19, 2018
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Finding in retinoblastoma could lead to new interventions Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the... Read More
Published on August 23, 2018
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CHLA investigators spotlight the need to include obese and overweight subjects in metabolic research to prevent potentially misleading outcomes.   Children's Hospital Los Angeles investigators have demonstrated the need to include a growing constituency of obese and... Read More
Published on June 27, 2018
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CHLA and USC researchers team up to design and implant a minimally-invasive device in area around the heart.   Investigators at Children's Hospital Los Angeles and the University of Southern California have demonstrated the feasibility of implanting a... Read More
Published on June 22, 2018
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Children's Hospital Los Angeles contributes to large, multisite international ‘Brainstorm’ Project   Investigators found that many common psychiatric disorders are deeply connected on a genetic level, sharing specific genetic risk factors, underscoring the need to... Read More
Published on June 20, 2018
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“We thought she had a bug bite,” says Michelle’s mom, “but it turned out to be cancer.” After seeing several doctors, the family was referred to Children’s Hospital Los Angeles. Because the team of specialists at CHLA had access to a specialized genetic test that they helped... Read More
Published on June 18, 2018
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Seattle Children’s, with participating members Children’s Hospital Los Angeles, Children’s National Health System and BC Children’s Hospital, has launched CureWorks, an international collaborative of leading academic children’s hospitals determined to accelerate the development... Read More
Published on May 24, 2018
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Pat Levitt, PhD, has been named Vice President, Chief Scientific Officer and Director of The Saban Research Institute of Children’s Hospital Los Angeles. Read More
Published on May 16, 2018
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Findings suggest new therapeutic approach for children with high-risk disease Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages—a type of... Read More
Published on May 16, 2018
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Investigators at Children’s Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium... Read More
Published on February 28, 2018
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Less-toxic lymphoid regimens are more likely to obtain remission in mixed phenotype acute leukemia (MPAL) A study at Children’s Hospital Los Angeles is shedding new light on the best therapeutic approach for a rare and aggressive leukemia called mixed phenotype acute... Read More
Published on February 27, 2018
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A landmark study published in the Journal of Neuroscience on February 26 reveals that activation of a pregnant mother’s immune system can affect her baby’s brain development. A team of researchers led by Bradley Peterson, MD, director of the Institute for the Developing Mind in... Read More
Published on February 21, 2018
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Three quarters of patients, both adults and children, with a variety of advanced cancers occurring in different sites of the body responded to larotrectinib, a novel therapy that targets a specific genetic mutation. Results of this multisite phase 1/2 trial have been published... Read More

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