Research News Listing

Published on March 4, 2016
140458177028_0.jpg “When I ask my patients, they tell me ‘no, I don’t smoke’,” says Diane Tanaka, MD, medical director of Adolescent and Young Adult Medicine at Children’s Hospital Los Angeles. “It wasn’t until I saw them with e-cigarettes that I realized that I wasn’t asking the right question.”... Read More
Published on March 2, 2016
140355056373_0.jpg Comparison of radiation exposure in x-ray based photon radiotherapy (left) and proton radiotherapy (right). Image source: Taheri-Kadkhoda et al. Radiation Oncology 2008 3:4 doi:10.1186/1748-717X-3-4, Creative Commons Attribution 2.0 Generic. Medulloblastoma, the most common... Read More
Published on February 29, 2016
140225307206_0.jpg Robert Seeger, MD, division head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) has been selected for the 2016 Lifetime Achievement Award from the Pediatric Blood and Marrow Transplant Consortium (PBMC... Read More
Published on February 27, 2016
The Flint, Michigan water crisis raises concerns about the effects of lead poisoning on children. According to the World Health Organization, lead poisoning accounts for 0.6% of the global burden of disease. Children are particularly susceptible to the effects of lead poisoning... Read More
Published on February 24, 2016
139934303326_0.jpg In 2006, researchers studying obesity stumbled upon a gene called PID1 (Phosphotyrosine Interaction Domain containing 1). They found the gene played a role in insulin resistance in obese patients, making it a target for development of new treatments for obesity.Three years after... Read More
Published on February 23, 2016
Robert Seeger, MD, sized.jpg Robert Seeger, MD, division head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) has been selected for the 2016 Lifetime Achievement Award from the Pediatric Blood and Marrow Transplant Consortium (PBMC... Read More
Published on February 21, 2016
139740916925_0.jpg A once relatively unknown virus has recently made headlines as over 4000 cases of severe birth defects connected to the virus have been reported in Brazil. The Zika virus is related to the dengue and west Nile viruses and has many researchers scrambling to uncover both how the... Read More
Published on February 18, 2016
139563568613_0.jpg Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research.  The assay would be CHLA’s first NGS panel designed to target biomarkers associated with... Read More
Published on February 18, 2016
shutterstock_232207735 (1).jpg Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research.  The assay would be CHLA’s first NGS panel designed to target biomarkers associated... Read More
Published on February 16, 2016
139435157244_0.jpg Normal lung (image A) compared to lung developed with low levels of VEGF (image B) demonstrating abnormal air spaces and lung tissue. Photo courtesy of Grikscheit Lab, The Saban Research Institute of Children’s Hospital Los AngelesInvestigators at The Saban Research Institute of... Read More
Published on February 14, 2016
139307198954_0.jpg Here we see proliferating cardiomyocytes or heart cells from zebrafish. Zebrafish, a tropical fish in the minnow family commonly used in scientific research, is known best for its regenerative abilities. Researchers at Children’s Hospital Los Angeles led by Ching-Ling Lien, PhD... Read More
Published on February 12, 2016
139177886233_0.jpg Patients with acute lymphoblastic leukemia are at increased risk for bone fractures due to bone loss resulting from treatment. This decrease in bone density (as illustrated here) can occur as soon as the first month of treatment according to new research out of Children’s... Read More
Published on February 10, 2016
139085056931_0.jpg Stickers proclaiming “BPA-free” status are increasingly common on plastic bottles. BPA or Bisphenol A was used at one point to increase the strength of plastic, though was phased out when studies demonstrated the chemical had several significant negative health. Since then, BPS... Read More
Published on February 10, 2016
GrikWieck PLOS web.jpg Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have created a novel model for studying a lung disorder of newborn babies. Their study, published in PLOS ONE on February 10, describes the first model that allows investigators to consider the... Read More
Published on February 8, 2016
138938483954_0.jpg Leukemia cells (yellow) shown dispersed among fat cells (red) surrounded by supportive cells (blue). Image courtesy of Steven Mittelman, MD, PhD, Children’s Hospital Los Angeles.An interdisciplinary research team at The Saban Research Institute of Children’s Hospital Los Angeles... Read More
Published on February 5, 2016
138742063027_0.jpg Throughout football season and leading up to the Super Bowl, an increase in ACL injuries is inevitable. Image courtesy of Shutterstock.A common and often devastating injury in sports – anterior cruciate ligament (ACL) injury can require surgery to restore knee stability... Read More
Published on February 4, 2016
Etan Orgel, MD, MS.jpg Investigators at Children’s Hospital Los Angeles have found that significant bone loss – a side effect of chemotherapy for acute lymphoblastic leukemia (ALL) – occurs during the first month of treatment, far earlier than previously assumed. Results of the study will be available... Read More
Published on February 3, 2016
138634500236_0.jpg Neuroblastoma cells under a microscope labeled with fluorescent molecules. Image courtesy of Shutterstock.Building upon more than two decades of basic research conducted at Children’s Hospital Los Angeles, Araz Marachelian, MD, of CHLA, and her colleagues at pediatric academic... Read More
Published on February 2, 2016
138568688258_0.jpg Food allergy or intolerance can cause symptoms ranging from a harmless skin rash to a potentially lethal anaphylactic shock. An estimated 15 million Americans suffer from food allergies, many of them children. The prevalence of food allergy is higher among children and is... Read More
Published on January 28, 2016
resize.jpg An interdisciplinary research team at The Saban Research Institute of Children’s Hospital Los Angeles has found that body mass index (BMI) is an inadequate method for estimating changes in body fat and obesity in children with leukemia. Investigators determined that the... Read More

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