Research News Listing

Published on March 24, 2016
MontageCellReportCHLA_PR-T 50% web.jpg A new study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) reports that the presence of leptin – a hormone secreted by fat cells that is critical to maintaining energy balance in the body -- inhibits the prenatal development of... Read More
Published on March 23, 2016
The scientific and healthcare communities have become increasingly aware of the profound impact that early life events have on the lifelong health and well-being of children and the adults they will become. Read More
Published on March 22, 2016
141509448912_0.jpg A new study out of Children’s Hospital Los Angeles has found excessive fat in legs of children with a severe form of spina bifida suggests increased risk for metabolic disordersRepresentative quantified computed tomography (CT) slices showing excess adipose or fatty tissues (... Read More
Published on March 22, 2016
Untitled2.jpg Douglas Nordli, Jr., MD, has been named chief of the Division of Pediatric Neurology and co-director of the Neurosciences Institute at Children’s Hospital Los Angeles (CHLA). Dr. Nordli, who will also serve as a vice chair of Neurology at the Keck School of Medicine of the... Read More
Published on March 18, 2016
141264235595_0.jpg Despite Increases in Screening, Study Finds Only 44 Percent of Pediatricians Inquire about Maternal DepressionMaternal depression affects up to 40 percent of mothers with young children and can have many negative effects on the infant and developing child including feeding... Read More
Published on March 17, 2016
Tracy C. Grikscheit, MD, web.jpg Grant will fund development of cellular therapy to treat digestive nerve disorders Tracy C. Grikscheit, MD, of The Saban Research Institute of Children’s Hospital Los Angeles has received a $7.1 million grant from the California Institute of Regenerative Medicine... Read More
Published on March 16, 2016
We are living through a revolution in biology that is giving us a deeper, sharper understanding about how early experience effects development of the brain. Read More
Published on March 14, 2016
141052537356_0.jpg Study suggests macrophage activation as possible reason for differential bone loss in adolescent malesActivation of macrophages – a type of immune cell which, in the bone, takes the form of bone-eating osteoclast cells (above) – may play a significant role in bone loss found in... Read More
Published on March 14, 2016
CT images 2 - nc, web.jpg Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities.  In a study designed to assess bone, muscle and fat tissue distribution in the lower legs of children with this... Read More
Published on March 10, 2016
140822617459_0.jpg Research suggests racism experienced in childhood can lead to health problems later in life.While overall health has improved, from reduced infant mortality to improved outcomes for a variety of diseases, racial and ethnic disparities in health remain a significant problem that... Read More
Published on March 10, 2016
cropped, web.jpg Study suggests macrophage activation as possible reason for differential bone loss in adolescent males Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division... Read More
Published on March 4, 2016
140458177028_0.jpg “When I ask my patients, they tell me ‘no, I don’t smoke’,” says Diane Tanaka, MD, medical director of Adolescent and Young Adult Medicine at Children’s Hospital Los Angeles. “It wasn’t until I saw them with e-cigarettes that I realized that I wasn’t asking the right question.”... Read More
Published on March 2, 2016
140355056373_0.jpg Comparison of radiation exposure in x-ray based photon radiotherapy (left) and proton radiotherapy (right). Image source: Taheri-Kadkhoda et al. Radiation Oncology 2008 3:4 doi:10.1186/1748-717X-3-4, Creative Commons Attribution 2.0 Generic. Medulloblastoma, the most common... Read More
Published on February 29, 2016
140225307206_0.jpg Robert Seeger, MD, division head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) has been selected for the 2016 Lifetime Achievement Award from the Pediatric Blood and Marrow Transplant Consortium (PBMC... Read More
Published on February 27, 2016
The Flint, Michigan water crisis raises concerns about the effects of lead poisoning on children. According to the World Health Organization, lead poisoning accounts for 0.6% of the global burden of disease. Children are particularly susceptible to the effects of lead poisoning... Read More
Published on February 24, 2016
139934303326_0.jpg In 2006, researchers studying obesity stumbled upon a gene called PID1 (Phosphotyrosine Interaction Domain containing 1). They found the gene played a role in insulin resistance in obese patients, making it a target for development of new treatments for obesity.Three years after... Read More
Published on February 23, 2016
Robert Seeger, MD, sized.jpg Robert Seeger, MD, division head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) has been selected for the 2016 Lifetime Achievement Award from the Pediatric Blood and Marrow Transplant Consortium (PBMC... Read More
Published on February 21, 2016
139740916925_0.jpg A once relatively unknown virus has recently made headlines as over 4000 cases of severe birth defects connected to the virus have been reported in Brazil. The Zika virus is related to the dengue and west Nile viruses and has many researchers scrambling to uncover both how the... Read More
Published on February 18, 2016
139563568613_0.jpg Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research.  The assay would be CHLA’s first NGS panel designed to target biomarkers associated with... Read More
Published on February 18, 2016
shutterstock_232207735 (1).jpg Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research.  The assay would be CHLA’s first NGS panel designed to target biomarkers associated... Read More

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