Research News Listing

Published on April 28, 2016
143540658942_0.jpg Evidence-based research proves they can with early educationA field trip to the local Ralph’s was a first for the Wiz Kids Preschool in Culver City, CA.  Thirty preschoolers between the ages of 3 and 5 were marched down Overland Avenue to shop for healthy food items from the... Read More
Published on April 25, 2016
143386022936_0.jpg In 2009, the Nobel Prize in Medicine was awarded for the discovery of telomerase, a previously little known protein that plays a key role in preventing damage to chromosomal DNA.“One of the recipients of the Nobel Prize, Dr. Elizabeth Blackburn, reminded us then that we are all... Read More
Published on April 21, 2016
143184293138_0.jpg Probiotics, bacteria believed to be beneficial for health, are thought to help with various gastrointestinal issues. A recent nationwide study published in the American Journal of Infection Control found it is common for hospitals to prescribe probiotics to patients with a... Read More
Published on April 19, 2016
143069411509_0.jpg Cultured retinoblastoma tumor containing tumor cells (red) and fibroblasts (green).  Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that targeting survivin – a protein that inhibits apoptosis or cell death – enhances the... Read More
Published on April 14, 2016
Retinoblastoma tumor cells, web.jpg Use of Chemotherapy with a Survivin Inhibitor Improves Treatment Responses in Retinoblastoma Cells and Ocular Tumor Models Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that targeting survivin – a protein that inhibits... Read More
Published on April 13, 2016
142748206550_0.jpg A staple of pediatric  healthcare, antibiotics are the most prescribed medication for children. However, the long-term effects of these medications remain relatively unknown. Last month, two studies looked into the links between antibiotic use and childhood obesity, finding... Read More
Published on April 11, 2016
Stem cell-derived retina, web.jpg Study seeks to improve understanding of light-sensitive cells in the retina that initiate daylight vision David E. Cobrinik, MD, PhD, of The Vision Center at Children’s Hospital Los Angeles (CHLA) has been awarded a four-year grant totaling $1.665 million from the National... Read More
Published on April 8, 2016
142469164948_0.jpg Shedding epithelial cells in the intestine. Image courtesy of Mark R. Frey, PhD, The Saban Research Institute, Children’s Hospital Los Angeles.The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a... Read More
Published on April 6, 2016
142359349425_0.jpg Children’s Hospital Los Angeles to Initiate Clinical Trial for Kids with Treatment-Resistant LeukemiaResearchers at Children’s Hospital Los Angeles will be testing a new therapy for acute lymphoblastic leukemia using specially engineered T-cells isolated from patients that can... Read More
Published on April 5, 2016
Frey_sheddingCells, web.jpg The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. Altered shedding is associated with multiple disorders,... Read More
Published on April 4, 2016
142262132902_0.jpg In a new editorial published in JAMA Pediatrics, Johanna Olson-Kennedy, MD, medical director of The Center for Transyouth Health and Development at Children’s Hospital Los Angeles discusses disparities in mental health in young transgender populations. A recent study, also... Read More
Published on March 31, 2016
142036641603_0.jpg Here we see the development of the brain-pancreas axis during gestation. According to a new study out of Children’s Hospital Los Angeles, the hormone leptin alters neuronal growth between the brain and pancreas during embryonic development, which may play a role in the onset of... Read More
Published on March 29, 2016
141922573798_0.jpg Eczema or atopic dermatitis is a condition where the areas of the skin are inflamed, resulting in symptoms ranging from redness to severe rashes and blisters. The specific causes of eczema remain unknown, though the condition has been linked to other conditions ranging from... Read More
Published on March 29, 2016
21386-chla-placeholders_320x165_v2_0.jpg Phase 1/Phase 2 study offers major new approach to treating cancer The Children’s Center for Cancer and Blood Diseases (CCCBD) at Children’s Hospital Los Angeles is one of the first sites in the world to offer a promising new investigational therapy to treat pediatric acute... Read More
Published on March 24, 2016
141624663167_0.jpg Children’s Hospital Los Angeles Awarded $7.1 Million by CIRM to develop new cellular therapy to treat digestive nerve disordersHirschsprung’s disease, where crucial nerve cells are absent in parts of the gastrointestinal tract resulting in the inability to properly push food... Read More
Published on March 24, 2016
MontageCellReportCHLA_PR-T 50% web.jpg A new study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) reports that the presence of leptin – a hormone secreted by fat cells that is critical to maintaining energy balance in the body -- inhibits the prenatal development of... Read More
Published on March 23, 2016
The scientific and healthcare communities have become increasingly aware of the profound impact that early life events have on the lifelong health and well-being of children and the adults they will become. Read More
Published on March 22, 2016
141509448912_0.jpg A new study out of Children’s Hospital Los Angeles has found excessive fat in legs of children with a severe form of spina bifida suggests increased risk for metabolic disordersRepresentative quantified computed tomography (CT) slices showing excess adipose or fatty tissues (... Read More
Published on March 22, 2016
Untitled2.jpg Douglas Nordli, Jr., MD, has been named chief of the Division of Pediatric Neurology and co-director of the Neurosciences Institute at Children’s Hospital Los Angeles (CHLA). Dr. Nordli, who will also serve as a vice chair of Neurology at the Keck School of Medicine of the... Read More
Published on March 18, 2016
141264235595_0.jpg Despite Increases in Screening, Study Finds Only 44 Percent of Pediatricians Inquire about Maternal DepressionMaternal depression affects up to 40 percent of mothers with young children and can have many negative effects on the infant and developing child including feeding... Read More

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