Research News Listing

Published on June 22, 2018
Pat Levitt, PhD.jpg Children's Hospital Los Angeles contributes to large, multisite international ‘Brainstorm’ Project   Investigators found that many common psychiatric disorders are deeply connected on a genetic level, sharing specific genetic risk factors, underscoring the need to... Read More
Published on June 20, 2018
21386-chla-placeholders_320x165_v2_0.jpg “We thought she had a bug bite,” says Michelle’s mom, “but it turned out to be cancer.” After seeing several doctors, the family was referred to Children’s Hospital Los Angeles. Because the team of specialists at CHLA had access to a specialized genetic test that they helped... Read More
Published on June 18, 2018
CureWorks_logo_w_tag_TM_jpg.jpg Seattle Children’s, with participating members Children’s Hospital Los Angeles, Children’s National Health System and BC Children’s Hospital, has launched CureWorks, an international collaborative of leading academic children’s hospitals determined to accelerate the development... Read More
Published on May 24, 2018
Levitt_Pat 5-sm.jpg LOS ANGELES -- Pat Levitt, PhD, has been named Vice President, Chief Scientific Officer and Director of The Saban Research Institute of Children’s Hospital Los Angeles. “In addition to being a distinguished scholar and brilliant scientist, Dr. Pat Levitt’s commitment to... Read More
Published on May 16, 2018
10E4_CHLA90_2[2] (tumor-associated macrophages) Findings suggest new therapeutic approach for children with high-risk disease Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages—a type of... Read More
Published on May 16, 2018
MRI of brain (1).jpg Investigators at Children’s Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium... Read More
Published on February 28, 2018
Etan Orgel.jpg Less-toxic lymphoid regimens are more likely to obtain remission in mixed phenotype acute leukemia (MPAL) A study at Children’s Hospital Los Angeles is shedding new light on the best therapeutic approach for a rare and aggressive leukemia called mixed phenotype acute... Read More
Published on February 27, 2018
CHLA-Bradley-Peterson.jpg Stress and other factors can trigger immune response A landmark study published in the Journal of Neuroscience on February 26 reveals that activation of a pregnant mother’s immune system can affect her baby’s brain development. A team of researchers led by Bradley Peterson,... Read More
Published on February 21, 2018
LM.jpg Children’s Hospital Los Angeles one of 25 sites in international study of larotrectinib Three quarters of patients, both adults and children, with a variety of advanced cancers occurring in different sites of the body responded to larotrectinib, a novel therapy that targets a... Read More
Published on February 5, 2018
Jasmine_HLHS Consortium web.jpg Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I... Read More
Published on February 1, 2018
Michael  Pulsipher, MD, CHLA3.jpg Detailed analysis of patient data now available Results of the global, multicenter, pivotal phase 2 study that led to the first FDA approval of a gene therapy/cell therapy approach known as CAR T-cell therapy, were published on January 31 in the New England Journal of... Read More
Published on December 14, 2017
Laura Perin, PhD_0 (1) 2017 web.jpg Study findings indicate a more effective way to slow organ damage in Alport syndrome Researchers have demonstrated for the first time that extracellular vesicles – tiny protein-filled structures – isolated from amniotic fluid stem cells (AFSCs) can be used to effectively... Read More
Published on November 20, 2017
CHLA-D.Brent Polk, MD.jpg Findings may point to new treatment approaches for patients with IBD D. Brent Polk, MD, AGAF, an investigator at Children’s Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of... Read More
Published on November 13, 2017
CHLA-St. Baldrick's Foundation check presentation at CHLA.jpg Three physician-researchers with the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) have been awarded more than $1 million in grants from the St. Baldrick’s Foundation, the largest private funder of childhood cancer research. The... Read More
Published on November 7, 2017
CHLA-Jeffrey-Gold.jpg Study finds that virtual reality is effective in reducing pain during certain medical procedures Virtual reality has emerged into popular culture with an ever-widening array of applications including clinical use in a pediatric healthcare center. Children undergo necessary... Read More
Published on November 6, 2017
CHLA-Pulsipher2.jpg New Cellular Therapy Approach for Children with Compromised Immune Systems Michael Pulsipher, MD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, along with Michael Keller, MD from Children’s National Health System in Washington, DC... Read More
Published on October 31, 2017
CHLA-Sheree Schrager, PhD.jpg   Findings expected to enable development of targeted and effective interventions for LGB youth at risk Sheree Schrager, PhD, MS, an investigator at Children's Hospital Los Angeles, and fellow investigator, Jeremy Goldbach, PhD, of the USC Suzanne Dworak-Peck... Read More
Published on October 18, 2017
MRI of newborn infant brain and 3-D image of subcortical structures.web_.jpg Findings expected to enable design of early interventions to improve healthy neurodevelopment Natasha Leporé, PhD, a principal investigator in the Department of Radiology and Imaging at Children’s Hospital Los Angeles, has been awarded $1.7 million from the National Institute... Read More
Published on October 12, 2017
Surgeons web.jpg Study indicates proof of concept for using a surrogate liquid biopsy to provide genetic profile of retinoblastoma tumors Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age. If not diagnosed early, retinoblastoma may result in loss of... Read More
Published on October 5, 2017
CHLA-Pulsipher2.jpg Children’s Hospital Los Angeles receives $9 million from NIH to study “bubble boy” syndrome Michael Pulsipher, MD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, along with co-principal investigator, Sung-Yun Pai, MD, of Boston... Read More

Pages