Research News Listing

Published on August 13, 2019
Glomerulus in vitro Scientists at Children’s Hospital Los Angeles develop first physiologically-accurate in vitro model of the human kidney glomerulus, representing a milestone in the field of kidney disease research. Kidneys work to constantly filter blood and remove toxins from the body.... Read More
Published on July 22, 2019
Frey Intestine.jpg Chemotherapy and radiation target cancer cells but these treatments produce unwanted side effects on healthy tissue. The intestines are particularly sensitive to this toxicity. A better understanding of how intestinal tissue repairs itself in response to injury could help... Read More
Published on July 1, 2019
vax photo.jpg Pediatricians have observed that a baby’s early infection with flu impacts their later response to the virus as well as how protected they are by vaccination. To better understand how this “immunological imprinting” occurs, the National Institute of Allergy and Infectious... Read More
Published on June 13, 2019
shutterstock_210747010.jpg For the future of medicine, clinicians and scientists at Children’s Hospital Los Angeles look to our genes. The age of one-size-fits-all medicine is fading. Taking its place is an era of personalized medicine – the practice of tailoring disease prevention, diagnosis, and... Read More
Published on June 7, 2019
grikscheit 2.JPG Pediatric surgeon Tracy Grikscheit of Children’s Hospital Los Angeles and colleagues describe the progress and challenges of building new intestinal tissue for babies in need. Babies born prematurely often face intense medical challenges, including intestines that are... Read More
Published on May 16, 2019
Pat Levitt, PhD.jpg Children’s Hospital Los Angeles researcher awarded $3.7M to study neural circuits associated with developmental disorders. Pat Levitt, PhD, Chief Scientific Officer at Children’s Hospital Los Angeles and Simms/Mann Chair in Developmental Neurogenetics, received a $3.7M grant... Read More
Published on April 26, 2019
Olch_Arthur_06-19-13(2).jpg Doctors at Children’s Hospital Los Angeles use novel software to improve accuracy of cancer treatment Doctors at Children’s Hospital Los Angeles continue to lead the field of radiation oncology by pushing the leading edge of technological advances. A new report by Arthur... Read More
Published on April 8, 2019
Levitt_Pat 5-sm.jpg Stress creates risk, maternal education provides resilience   A study of 70 mothers and their infants suggests that the impact of maternal stress on neurodevelopment is detectable by electroencephalography (EEG) at 2 months of age. The team of investigators, co-led... Read More
Published on April 5, 2019
Williams_Marian_0955 (2).jpg Clinical psychologists implement child-parent psychotherapy in The Steven & Alexandra Cohen Foundation Newborn and Infant Critical Care Unit at Children's Hospital Los Angeles Bringing a baby into the world involves many firsts – mothers and fathers are discovering their... Read More
Published on March 15, 2019
CPM pipet.png Considering the implications of precision medicine for diagnosis and treatment of pediatric cancers   Research performed over the last several decades has led to an increased understanding of the genetics of cancer. The clinical application of this knowledge for... Read More
Published on March 14, 2019
Cobrinik cones.jpg CHLA researcher receives $1.6M grant to study cellular and genetic changes that underlie retinoblastoma. Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age and accounts for approximately 4% of childhood cancers. If not diagnosed... Read More
Published on February 28, 2019
CHLA-Jennifer-Raymond.jpg Children’s Hospital Los Angeles has been awarded a $1.36M grant from The Leona M. and Harry B. Helmsley Charitable Trust to adapt a patient-driven model of care that Clinical Diabetes Director, Jennifer Raymond, MD, MCR, developed to increase treatment compliance among difficult... Read More
Published on February 7, 2019
John Wood scan crop.png Research at Children’s Hospital Los Angeles brings us closer to understanding an elusive complication of sickle cell disease – the silent stroke. Sickle Cell Disease (SCD) is rare but devastating. Due to a genetic mutation affecting hemoglobin, the component of the red blood... Read More
Published on January 30, 2019
Dr. Peterson _0008.jpg With autism on the rise, science is on the hunt for answers. New research at Children’s Hospital Los Angeles looks at autism in a different way. One in 59 children are diagnosed with an Autism Spectrum Disorder (ASD), a wide array of conditions affecting a child’s social,... Read More
Published on January 25, 2019
Javier Grandparents (3).jpg How one doctor born and raised in a tightly knit Filipino culture is poised to dramatically improve the health and well-being of her community Mental health and suicide are not just adult issues. According to the Centers for Disease Control and Prevention, suicide rates have... Read More
Published on January 23, 2019
Melanocortin2.jpg Scientists are piecing together how genes involved in neural development can affect body weight Leading a unique, collaborative research study with scientists across the globe, investigators at the University of Cambridge and Children’s Hospital Los Angeles have pinpointed a... Read More
Published on December 20, 2018
CHLA-Yong-Mi-Kim-Headshot (2).jpg Investigator Yong-Mi Kim works to uncover how the body shields leukemia cells from treatment   Acute Lymphoblastic Leukemia (ALL) is the most prevalent childhood cancer, with more than 3,000 new cases reported each year. The majority of patients with ALL survive... Read More
Published on December 5, 2018
Yves De Clerck.jpg New study reveals how cancer manipulates our immune system to become harder to treat Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so... Read More
Published on December 5, 2018
Grikscheit_Tracy_03-24-13-2.jpg Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality. She has been awarded nearly $1.3 million by the... Read More
Published on October 24, 2018
CHLA-Khemani-Robinder-782x439-Thumb.jpg An international team, led by Children’s Hospital Los Angeles, issues key findings on Pediatric Acute Respiratory Distress Syndrome LOS ANGELES — According to a first-of-its-kind international study, a new definition of Pediatric Acute Respiratory Distress Syndrome (... Read More

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