Research News Listing

Published on March 31, 2020
Leukemia_Hero.png CHLA scientists work toward a new therapy to target resistant leukemia.  In CAR-T therapy, a patient’s own immune system cells—called T-cells—are isolated and genetically modified to recognize CD-19, a protein (antigen) found on leukemia cells. A few years ago, this... Read More
Published on February 28, 2020
183313552487_0.jpg They wear lab coats in place of capes, safety goggles instead of masks, and wield pipets - not swords. But they are still our heroes.Feb 11th was International Day of Women and Girls in Science, and March 8th is International Women's Day. Did you know that more than half of... Read More
Published on February 20, 2020
Dr Wu transport.jpg LOS ANGELES (Feb. 20, 2020) — When a newborn suffers lack of oxygen before or during birth, doctors have very little time to save precious brain tissue. The only proven effective way to treat babies with hypoxic brain injuries is by reducing body temperature through controlled... Read More
Published on February 12, 2020
CHLA-Michael-Goran-4.jpg LOS ANGELES (Feb. 12, 2020) — Maternal factors, such as breast milk, have been shown to affect a baby’s development, and previous animal studies have determined that a carbohydrate, the oligosaccharide 2’FL found in maternal milk, positively influences neurodevelopment. Now, in... Read More
Published on February 3, 2020
CHLA-Blog-TSRI-Symposium-flyer-thumbnail.jpg The Saban Research Institute’s Annual Symposium will take place on February 19, 2020. This year’s theme is Health Complexities in Pediatrics: Investigating Systems in Action and Interaction The Saban Research Institute Annual Symposium highlights exciting strides that... Read More
Published on January 13, 2020
Cortex.png Researchers at Children’s Hospital Los Angeles reveal a relationship between lead exposure risk and brain structure in children from lower-income families Though leaded gas and lead-based paint were banned decades ago, the risk of lead exposure is far from gone. A new study... Read More
Published on November 13, 2019
189042545072_0.jpg Scientists at Children’s Hospital Los Angeles discover a mechanism that zebrafish use to regenerate damaged heart tissue. This research could lead to better treatments for babies in need of heart repair.Cardiac lymphatic vessels (seen here in red) in the zebrafish heart help the... Read More
Published on November 12, 2019
MHarrison Researchers at Children’s Hospital Los Angeles discover a mechanism of cardiac regeneration in the zebrafish that could change the field of heart research One of the reasons coronary heart disease is so deadly is that fluid build-up and scarring can develop in the heart... Read More
Published on November 4, 2019
160A0154.jpg Children’s Hospital Los Angeles Investigator researches a novel way to biopsy an aggressive childhood cancer Retinoblastoma is a cancer that forms in the light-detecting cells in the back of the eye. It often appears in children under two years of age and can lead to... Read More
Published on October 21, 2019
188497553267_0.jpg The invention of interactive map applications has revolutionized wayfinding, providing an unprecedented level of information far beyond what printed road maps can offer. Researchers at Children’s Hospital Los Angeles are giving us a similar look into the anatomy of the human... Read More
Published on October 17, 2019
CHLA-Denise AlAlam (1).jpg Researchers at Children’s Hospital Los Angeles make a critical advance in the field of lung research The invention of interactive map applications has revolutionized wayfinding, providing an unprecedented level of information far beyond what printed road maps can offer.... Read More
Published on September 25, 2019
Brain wiring graphic.jpg Researchers correlate brain anatomy and metabolism with behavioral development In a first-of-its-kind study, Children’s Hospital Los Angeles researchers piece together a road map of typical brain development in children during a critical window of maturation. The study shows... Read More
Published on September 6, 2019
187536381922_0.jpg California’s first Surgeon General, Dr. Nadine Burke Harris, visits Children’s Hospital Los AngelesOne of the reasons to conduct research at a pediatric institution is that getting evidence-based answers sooner can lead to real changes in health outcomes for children. These... Read More
Published on August 13, 2019
186981381687_0.jpg Scientists at Children’s Hospital Los Angeles develop first physiologically-accurate in vitro model of the human kidney glomerulus, representing a milestone in the field of kidney disease researchKidneys work to constantly filter blood and remove toxins from the body. Conditions... Read More
Published on August 13, 2019
Glomerulus in vitro Scientists at Children’s Hospital Los Angeles develop first physiologically-accurate in vitro model of the human kidney glomerulus, representing a milestone in the field of kidney disease research. Kidneys work to constantly filter blood and remove toxins from the body.... Read More
Published on July 22, 2019
Frey Intestine.jpg Chemotherapy and radiation target cancer cells but these treatments produce unwanted side effects on healthy tissue. The intestines are particularly sensitive to this toxicity. A better understanding of how intestinal tissue repairs itself in response to injury could help... Read More
Published on July 1, 2019
vax photo.jpg Pediatricians have observed that a baby’s early infection with flu impacts their later response to the virus as well as how protected they are by vaccination. To better understand how this “immunological imprinting” occurs, the National Institute of Allergy and Infectious... Read More
Published on June 13, 2019
shutterstock_210747010.jpg For the future of medicine, clinicians and scientists at Children’s Hospital Los Angeles look to our genes. The age of one-size-fits-all medicine is fading. Taking its place is an era of personalized medicine – the practice of tailoring disease prevention, diagnosis, and... Read More
Published on June 7, 2019
grikscheit 2.JPG Pediatric surgeon Tracy Grikscheit of Children’s Hospital Los Angeles and colleagues describe the progress and challenges of building new intestinal tissue for babies in need. Babies born prematurely often face intense medical challenges, including intestines that are... Read More
Published on May 17, 2019
184942176217_0.jpg When it comes to pediatric brain cancers, research and treatments have made great strides. But some cancers do not respond to conventional treatments or grow deep within delicate areas of the brain, where surgical removal can be impossible.Peter Chiarelli, MD, PhD, has received... Read More

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