Research News Listing

Published on February 5, 2018
Jasmine_HLHS Consortium web.jpg Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I... Read More
Published on February 1, 2018
Michael  Pulsipher, MD, CHLA3.jpg Detailed analysis of patient data now available Results of the global, multicenter, pivotal phase 2 study that led to the first FDA approval of a gene therapy/cell therapy approach known as CAR T-cell therapy, were published on January 31 in the New England Journal of... Read More
Published on December 14, 2017
Laura Perin, PhD_0 (1) 2017 web.jpg Study findings indicate a more effective way to slow organ damage in Alport syndrome Researchers have demonstrated for the first time that extracellular vesicles – tiny protein-filled structures – isolated from amniotic fluid stem cells (AFSCs) can be used to effectively... Read More
Published on November 20, 2017
CHLA-D.Brent Polk, MD.jpg Findings may point to new treatment approaches for patients with IBD D. Brent Polk, MD, AGAF, an investigator at Children’s Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of... Read More
Published on November 13, 2017
CHLA-St. Baldrick's Foundation check presentation at CHLA.jpg Three physician-researchers with the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) have been awarded more than $1 million in grants from the St. Baldrick’s Foundation, the largest private funder of childhood cancer research. The... Read More
Published on November 7, 2017
CHLA-Jeffrey-Gold.jpg Study finds that virtual reality is effective in reducing pain during certain medical procedures Virtual reality has emerged into popular culture with an ever-widening array of applications including clinical use in a pediatric healthcare center. Children undergo necessary... Read More
Published on November 6, 2017
CHLA-Pulsipher2.jpg New Cellular Therapy Approach for Children with Compromised Immune Systems Michael Pulsipher, MD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, along with Michael Keller, MD from Children’s National Health System in Washington, DC... Read More
Published on October 31, 2017
CHLA-Sheree Schrager, PhD.jpg   Findings expected to enable development of targeted and effective interventions for LGB youth at risk Sheree Schrager, PhD, MS, an investigator at Children's Hospital Los Angeles, and fellow investigator, Jeremy Goldbach, PhD, of the USC Suzanne Dworak-Peck... Read More
Published on October 18, 2017
MRI of newborn infant brain and 3-D image of subcortical structures.web_.jpg Findings expected to enable design of early interventions to improve healthy neurodevelopment Natasha Leporé, PhD, a principal investigator in the Department of Radiology and Imaging at Children’s Hospital Los Angeles, has been awarded $1.7 million from the National Institute... Read More
Published on October 12, 2017
Surgeons web.jpg Study indicates proof of concept for using a surrogate liquid biopsy to provide genetic profile of retinoblastoma tumors Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age. If not diagnosed early, retinoblastoma may result in loss of... Read More
Published on October 5, 2017
CHLA-Pulsipher2.jpg Children’s Hospital Los Angeles receives $9 million from NIH to study “bubble boy” syndrome Michael Pulsipher, MD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, along with co-principal investigator, Sung-Yun Pai, MD, of Boston... Read More
Published on September 21, 2017
CHLA-Shahab-Asgharzadeh.jpg Investigators identify pathway that causes immune cells to support cancer, instead of killing it Investigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles have identified new findings about an immune cell – called a tumor-... Read More
Published on September 6, 2017
CHLA-Pulsipher2.jpg Funding supports clinical research to improve early immune suppression-free survival for young patients with severe aplastic anemia Michael Pulsipher, MD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles has been awarded $1.3 million... Read More
Published on September 5, 2017
CHLA-DeClerck -Saban_Symposium.jpg NIH awards $2.2 million to fund collaborative research on exosomes Cancer metastasis – the spread of disease from the original site to a distant organ – remains a major challenge in treating cancer and a main cause of morbidity and mortality. A widely accepted explanation for... Read More
Published on August 28, 2017
Newborn baby on mechanical ventilator, shutterstock, web.jpg CTIP awards initial funding towards “catalyzing pediatric innovation” The Southern California Consortium for Technology and Innovation in Pediatrics (CTIP), based at Children's Hospital Los Angeles, has awarded $165,000 in seed grants to accelerate projects specifically... Read More
Published on August 22, 2017
CHLA-fMRI-Obesity-shutterstock.jpg Study uses fMRI to observe relationship between neurological activity and risk for obesity A team of researchers, including senior investigator, Bradley Peterson, MD, director of the Institute for the Developing Mind at Children’s Hospital Los Angeles, used fMRI to... Read More
Published on August 15, 2017
CHLA-Fabbri-Muller web.jpg Muller Fabbri, MD, PhD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, has been awarded $1.9 million by the National Cancer Institute of the NIH to further his research on neuroblastoma – the third most common type of childhood cancer... Read More
Published on August 9, 2017
21386-chla-placeholders_320x165_v2_0.jpg More accurate diagnoses translate to more effective treatment and better outcomes Investigators at Children's Hospital Los Angeles have succeeded in better defining a rare pediatric malignant liver disease — a necessary step in achieving an optimum treatment. The research... Read More
Published on August 7, 2017
21386-chla-placeholders_320x165_v2_0.jpg Preparing health care professionals to care for the next generation of adolescents and young adults Is California prepared to meet the specialized healthcare needs of the next generation of teens? According to the American Board of Pediatrics, there are only 51 physicians in... Read More
Published on July 10, 2017
CHLA-Guy-Young.jpg New therapy decreases incidence of bleeding by nearly 90% An international team of hematologists including Guy Young, MD, of Children’s Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, decreases incidence... Read More

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