Thomas C. Hofstra, MD

Attending Physician; Hematology, Oncology and Blood and Marrow Transplantation
Assistant Professor of Pediatrics, Keck School of Medicine of USC

Dr. Hofstra is an Assistant Professor of Pediatrics at the Keck School of Medicine. His clinical interests are in nonmalignant hematology, including inherited and acquired anemias, platelet disorders, hemoglobin disorders, sickle cell disease, thalassemia, bone marrow failure syndromes and clotting disorders. Dr. Hofstra has a long-standing interest in and is actively involved in medical student, resident and hematology/oncology fellowship education.

Clinical Interests

Nonmalignant hematology
Sickle cell disease
Bone marrow failure
Special interest in blood conservation (bloodless medicine)


Medical School

Loyola University Stritch School Medicine


Combined Internal Medicine/Pediatrics - Loyola University


Combined Internal Medicine/Pediatrics - Loyola University


Pediatric Hematology/Oncology - Children’s Hospital Los Angeles



Pediatrics: American Board of Pediatrics
Pediatric Hematology-Oncology: American Board of Pediatrics


American Society of Pediatric Hematology/Oncology (ASPHO)

Medical Awards

Best Doctors in America
Children’s Hospital Los Angeles Humanism Award
Walter Laug Pediatric Hematology/Oncology for Fellowship Education Teaching Award
Philip Roth Residency Teaching Award
Children's Hospital Los Angeles Research Fellowship Award
Phagocytosis in Chronic Neutrophil Activation States
Young Scientists Training Program



Franklin J, Church J, Kapoor N, Ortega J, Mascarenhas L, Hofstra TC, Weinberg K, Chu J, Anderson C, Rowland J: Childhood Non-Hodgkin’s Lymphomas (NHL) in acquired and congenital immunodeficiency patients. BLOOD 94;10(1), 2009.

Claster S, Carson S, Hofstra TC, Coates T, Wood J: Low ascorbate levels in transfused patients are associated with correlates of vascular damage in sickle cell disease. BLOOD 114(29), 2009.

Puliyel M, Sposto R, Berdoukas VA, Hofstra TC, Nord A, Carson S, Wood J, Coates TD.,  Ferritin trends do not predict changes in total body iron in patients with transfusional iron overload Am J Hematol. 2013 Dec 17.


Research Summary

Sickle cell disease